Results 11 to 20 of about 502,486 (298)

The glutamate post-synaptic density in schizophrenia [PDF]

open access: yes, 2012
Non-competitive antagonists of the glutamate N-methyl-D-aspartate receptor (NMDAR) induce a broad range of schizophrenia-like symptoms in humans.
Matas, Emmanuel
core   +7 more sources

Antibodies to the glutamate dehydrogenase of Plasmodium falciparum [PDF]

open access: yes, 1986
Polyclonal antisera raised against Plasmodium knowlesi reacted with NADP-specific glutamate dehydrogenase (GLDH) of P. knowlesi, GLDH of P. falciparum and GLDH of Proteus spp. The antisera did not react with NAD(P) GLDH from bovine liver.
Cooksley, S   +4 more
core   +4 more sources

Transient coating of γ-Fe2O3 nanoparticles with glutamate for its delivery to and removal from brain nerve terminals

open access: yesBeilstein Journal of Nanotechnology, 2020
Glutamate is the main excitatory neurotransmitter in the central nervous system and excessive extracellular glutamate concentration is a characteristic feature of stroke, brain trauma, and epilepsy.
Konstantin Paliienko   +5 more
doaj   +1 more source

Glutamine synthetase expression rescues human dendritic cell survival in a glutamine-deprived environment

open access: yesFrontiers in Oncology, 2023
IntroductionGlutamine deficiency is a well-known feature of the tumor environment. Here we analyzed the impact of glutamine deprivation on human myeloid cell survival and function.MethodsDifferent types of myeloid cells were cultured in the absence or ...
Robert Schoeppe   +21 more
doaj   +1 more source

The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes [PDF]

open access: yes, 2009
The pharmacology of Caenorhabditis elegans glutamate-gated chloride (GluCl) channels was determined by making intracellular voltage-clamp recordings from Xenopus oocytes expressing GluCl subunits. As previously reported (Cully et al.
Bush, Elizabeth   +3 more
core   +1 more source

In vivo co-ordinated interactions between inhibitory systems to control glutamate mediated hippocampal excitability. [PDF]

open access: yes, 2013
We present an overview of the long-term adaptation of hippocampal neurotransmission to cholinergic and GABAergic deafferentation caused by excitotoxic lesion of the medial septum.
Rodríguez Allué, Manuel José   +3 more
core   +1 more source

Pivotal Enzyme in Glutamate Metabolism of Poly-g-Glutamate-Producing Microbes

open access: yesLife, 2013
The extremely halophilic archaeon Natrialba aegyptiaca secretes the L-homo type of poly-g-glutamate (PGA) as an extremolyte. We examined the enzymes involved in glutamate metabolism and verified the presence of L-glutamate dehydrogenases, L-aspartate ...
Tohru Kamei   +2 more
doaj   +1 more source

Glutamate, Glutamate Receptors, and Downstream Signaling Pathways [PDF]

open access: yesInternational Journal of Biological Sciences, 2013
Glutamate is a nonessential amino acid, a major bioenergetic substrate for proliferating normal and neoplastic cells, and an excitatory neurotransmitter that is actively involved in biosynthetic, bioenergetic, metabolic, and oncogenic signaling pathways. Glutamate signaling activates a family of receptors consisting of metabotropic glutamate receptors (
Willard, Stacey S.   +1 more
openaire   +2 more sources

The influence of MK-801, glutamate and glycine via the modulation of N-methyl-D-aspartate receptors on isolated rat heart

open access: yesСеченовский вестник, 2020
N-methyl-D-aspartate (NMDA) receptors belong to the group of inotropic glutamate receptors, which are found in rat cardiomyocytes.Aim. To evaluate the influence of a non-competitive antagonist of NMDA-receptors — МК-801, separately or in combination with
N. S. Govorushkina   +11 more
doaj   +1 more source

Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]

open access: yes, 2004
The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Portman, Scott L.   +5 more
core   +1 more source

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