Results 11 to 20 of about 662,038 (354)
Brain and Neuroscience Advances, 2020 The ketamine metabolite (2 R ,6 R )-hydroxynorketamine has been proposed to have rapid and persistent antidepressant actions in rodents, but its mechanism of action is controversial.
Heather Kang +8 more
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Astrocyte Glutamate Uptake and Signaling as Novel Targets for Antiepileptogenic Therapy
Frontiers in Neurology, 2020 Astrocytes regulate and respond to extracellular glutamate levels in the central nervous system (CNS) via the Na+-dependent glutamate transporters glutamate transporter-1 (GLT-1) and glutamate aspartate transporter (GLAST) and the metabotropic glutamate ...
Allison R. Peterson, Devin K. Binder
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Glutamate-evoked currents in oocytes injected with CrGluCl-C cRNA. [PDF]
, 2023 A. Current traces obtained at the indicated membrane potentials during bath application of increasing glutamate concentrations as indicated by the boxes. B.
L. Pablo Cid (14790836) +4 more
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Beilstein Journal of Nanotechnology, 2020 Glutamate is the main excitatory neurotransmitter in the central nervous system and excessive extracellular glutamate concentration is a characteristic feature of stroke, brain trauma, and epilepsy.
Konstantin Paliienko +5 more
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Frontiers in Physiology, 2022 The brainstem nucleus tractus solitarii (nTS) processes and modulates the afferent arc of critical peripheral cardiorespiratory reflexes. Sensory afferents release glutamate to initiate the central component of these reflexes, and glutamate concentration
Diana Martinez +5 more
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The actions of chloride channel blockers, barbiturates and a benzodiazepine on Caenorhabditis elegans glutamate- and ivermectin-gated chloride channel subunits expressed in Xenopus oocytes [PDF]
, 2009 The pharmacology of Caenorhabditis elegans glutamate-gated chloride (GluCl) channels was determined by making intracellular voltage-clamp recordings from Xenopus oocytes expressing GluCl subunits. As previously reported (Cully et al.
Bush, Elizabeth +3 more
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Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor [PDF]
The Journal of Physical Chemistry B, 2017 Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is transmitted to the transmembrane region, opening the ...
Alvin Yu, Albert Y. Lau
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Regulation of the Maturation of Osteoblasts and Osteoclastogenesis by Glutamate [PDF]
, 2009 A B S T R A C T Glutamate, an important central excitatory neurotransmitter, is also secreted by osteoblasts and may be involved in the regulation of bone metabolism.
LIN, TZU-HUNG;YANG, RONG-SEN;TANG, CHIH -HSIN;WU, MING-YUEH;FU, WEN-MEI +1 more
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Glutamate-activated currents of CrGluCl-B cRNA-injected Xenopus oocytes. [PDF]
, 2023 A. Current traces obtained at the indicated membrane potentials during bath application of glutamate at concentrations from 10 μM to 3 mM, or 3 μM ivermectin during the times shown in the boxes. B.
L. Pablo Cid (14790836) +4 more
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Frontiers in Oncology, 2023 IntroductionGlutamine deficiency is a well-known feature of the tumor environment. Here we analyzed the impact of glutamine deprivation on human myeloid cell survival and function.MethodsDifferent types of myeloid cells were cultured in the absence or ...
Robert Schoeppe +21 more
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