Results 41 to 50 of about 511,305 (158)
Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]
, 2006 The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core +4 more sources
Neuronal activity determines distinct gliotransmitter release from a single astrocyte
eLife, 2018 Accumulating evidence indicates that astrocytes are actively involved in brain function by regulating synaptic activity and plasticity. Different gliotransmitters, such as glutamate, ATP, GABA or D-serine, released form astrocytes have been shown to ...
Ana Covelo, Alfonso Araque
doaj +1 more source
Frontiers in Synaptic Neuroscience, 2023 The unitary postsynaptic response to presynaptic quantal glutamate release is the fundamental basis of excitatory information transfer between neurons.
Graham M. Pitcher +6 more
doaj +1 more source
Microglial glutathione and glutamate: regulation mechanisms [PDF]
, 2009 Microglia, the immune cells of the central nervous system (CNS), are important in the protection of the CNS, but may be implicated in the pathogenesis of neuroinflammatory disease.
Fry, V.A.H.
core
Pharmaceuticals, 2021 The disturbed metabolism of vitamins B1 or B6, which are essential for neurotransmitters homeostasis, may cause seizures. Our study aims at revealing therapeutic potential of vitamins B1 and B6 by estimating the short- and long-term effects of their ...
Vasily A. Aleshin +8 more
doaj +1 more source
Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina [PDF]
, 2005 PURPOSE: Kinetic studies of photoreceptor cell death in the retinal degeneration (rd1) mouse model suggest that photoreceptor degeneration could result from cumulative damage.
Neveux, N +5 more
core
Glutamate-NMDA induces migration of microglia to the PNS.
, 2019 (A) Quantification of the average number of new debris from PNS-primed microglia collected at the secondary injury site compared to naïve CNS microglia (p = 0.0273).
Julia C. Nebiolo (6393221) +2 more
core +1 more source
Neuronal vs glial glutamate uptake: Resolving the conundrum [PDF]
, 2016 Neither normal brain function nor the pathological processes involved in neurological diseases can be adequately understood without knowledge of the release, uptake and metabolism of glutamate.
core +1 more source
A role for tumor necrosis factor-α in ischemia and ischemic preconditioning
Journal of Neuroinflammation, 2011 During cerebral ischemia, elevation of TNF-α and glutamate to pathophysiological levels may induce dysregulation of normal synaptic processes, leading ultimately to cell death.
O'Connor John J, Watters Orla
doaj +1 more source
Fishes, 2021 AlaSerCys Transporter 2 (ASCT2), encoded by the SLC1A5 gene, plays an important role in the absorption of glutamine. In this study, the full-length cDNA sequence of ASCT2 was cloned from triploid crucian carp.
Zhuangwen Mao +10 more
doaj +1 more source