Results 51 to 60 of about 662,038 (354)

Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

Frontiers in Neuroscience, 2023
ObjectiveTo determine sex differences in the neurochemical concentrations measured by in vivo proton magnetic resonance spectroscopy (1H MRS) of healthy mice on a genetic background commonly used for neurodegenerative disease models.Methods1H MRS data ...
Ivan Tkáč, Tiankai Xie, Nitya Shah, Sarah Larson, Janet M. Dubinsky, Rocio Gomez-Pastor, Hayley S. McLoughlin, Harry T. Orr, Lynn E. Eberly, Lynn E. Eberly, Gülin Öz   +10 more
doaj   +1 more source

d-glutamate and Gut Microbiota in Alzheimer’s Disease

International Journal of Molecular Sciences, 2020
Background: An increasing number of studies have shown that the brain–gut–microbiota axis may significantly contribute to Alzheimer’s disease (AD) pathogenesis. Moreover, impaired memory and learning involve the dysfunction neurotransmission of glutamate,
ChunLang Chang, Chieh-Hsin Lin, H. Lane
semanticscholar   +1 more source

Screening of High Yielding Antioxidant Peptide Bacillus sphaericus and Its Application in Value-added Utilization of Soybean Residue

Shipin gongye ke-ji
Objective: Soybean residue, a major by-product of soybean processing, possess nutritional value but have low industrial utilization due to low digestibility and poor palatability.
Qu LIU, Feiyu AN, Rina WU, Ye TIAN, Zhen TIAN, Guoyang PAN, Jinhui JIANG, Xinyu TAO, Yuanyuan MA, Junrui WU   +9 more
doaj   +1 more source

Molecular Mechanisms of Glutamate Toxicity in Parkinson’s Disease

Frontiers in Neuroscience, 2020
Parkinson’s disease (PD) is a common neurodegenerative disease, the pathological features of which include the presence of Lewy bodies and the neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta.
Ji Wang, Fushun Wang, Dongmei Mai, Shaogang Qu   +3 more
semanticscholar   +1 more source

Glutamate-NMDA induces migration of microglia to the PNS. [PDF]

, 2019
(A) Quantification of the average number of new debris from PNS-primed microglia collected at the secondary injury site compared to naïve CNS microglia (p = 0.0273).
Julia C. Nebiolo (6393221), Lauren A. Green (6393218), Cody J. Smith (637052)   +2 more
core   +1 more source

A mini-review of the role of vesicular glutamate transporters in Parkinson’s disease

Frontiers in Molecular Neuroscience, 2023
Parkinson’s disease (PD) is a common neurodegenerative disease implicated in multiple interacting neurotransmitter pathways. Glutamate is the central excitatory neurotransmitter in the brain and plays critical influence in the control of neuronal ...
Cheng Zhao, Cheng Zhao, Cheng Zhao, Chunyu Wang, Hainan Zhang, Weiqian Yan   +5 more
doaj   +1 more source

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

eLife, 2014
Exchange of extracellular cystine for intracellular glutamate by the antiporter system xc− is implicated in numerous pathologies. Pharmacological agents that inhibit system xc− activity with high potency have long been sought, but have remained elusive ...
S. Dixon, Darpan N. Patel, Matthew E. Welsch, R. Skouta, Eric D. Lee, M. Hayano, A. Thomas, Caroline E. Gleason, Nicholas P. Tatonetti, B. Slusher, B. Stockwell   +10 more
semanticscholar   +1 more source

Neuronal vs glial glutamate uptake: Resolving the conundrum [PDF]

, 2016
Neither normal brain function nor the pathological processes involved in neurological diseases can be adequately understood without knowledge of the release, uptake and metabolism of glutamate.

core   +1 more source

Glutamate Metabolism in Brain Structures in Experimental Hemorrhagic Shock

Общая реаниматология, 2017
Purpose. To study glutamate metabolism characteristics in phylogenetically different parts of the mammalian brain in experimentally induced hemorrhagic shock (HS) in cats.Material and methods. Experiments were performed on 76 cats.
V. N. Jakovlev, P. N. Savilov, Y. V. Bulgakova   +2 more
doaj   +1 more source

Glutamatergic neurometabolite levels in the caudate are associated with the ability of rhythm production

Frontiers in Neuroscience, 2023
IntroductionGlutamatergic neurometabolites play important roles in the basal ganglia, a hub of the brain networks involved in musical rhythm processing.
Shiori Honda, Yoshihiro Noda, Karin Matsushita, Ryosuke Tarumi, Ryosuke Tarumi, Natsumi Nomiyama, Sakiko Tsugawa, Yui Tobari, Nobuaki Hondo, Keisuke Saito, Masaru Mimura, Shinya Fujii, Shinichiro Nakajima, Shinichiro Nakajima   +13 more
doaj   +1 more source