Results 1 to 10 of about 3,871 (89)

Surface Grafting of Poly(L-glutamates). 3. Block Copolymerization [PDF]

, 2001
This paper describes for the first time the synthesis of surface-grafted AB-block copolypeptides, consisting of poly(γ-benzyl L-glutamate) (PBLG) as the A-block and poly(γ-methyl L-glutamate) (PMLG) as the B-block.
Chang Y. C., Chang Y. C., Duda G., Enriquez E. P., Hadziioannou G., Halperin A., Heise A., Hickel W., Hol W. G., Imanishi Y., Ivanov A. E., Jaworek T., Kricheldorf H., Machida S., Milner S., Miyazawa T., Napper D. H., Niwa M., Oosterling M. L. C. M., Oosterling M. L. C. M., Stamm M., Whitesell J. K., Whitesell J. K., Whitesell J. K., Wieringa R. H., Wieringa R. H., Wieringa R. H., Worly C. G., Wu S.   +28 more
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Glutamate and reinstatement [PDF]

Current Opinion in Pharmacology, 2009
The importance of glutamate in the reinstatement of cocaine-seeking behavior has been established. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal glutamate levels and the involvement of the GluR1 receptor subunit in
Lori A. Knackstedt, Peter W. Kalivas
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The glutamate story [PDF]

British Journal of Pharmacology, 2006
Glutamatergic synaptic transmission in the mammalian central nervous system was slowly established over a period of some 20 years, dating from the 1950s. Realisation that glutamate and like amino acids (collectively known as excitatory amino acids (EAA)) mediated their excitatory actionsviamultiple receptors preceded establishment of these receptors as
Watkins, JC, Jane, DE
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Production ofD-Glutamate fromL-Glutamate with Glutamate Racemase andL-Glutamate Oxidase [PDF]

Bioscience, Biotechnology, and Biochemistry, 1999
We studied production of D-glutamate from L-glutamate using a bioreactor consisting of two columns of sequentially connected immobilized glutamate racemase (EC 5.1.1.3, from Bacillus subtilis IFO 3336) and L-glutamate oxidase (EC 1.4.3.11, from Streptomyces sp.
Tadao Oikawa, Kazuhiro Yamade, Hidemi Makiura, Hitoshi Kusakabe, Kenji Soda, Mayumi Watanabe   +5 more
openaire   +3 more sources

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice. [PDF]

, 2015
Glycine decarboxylase (GLDC) acts in the glycine cleavage system to decarboxylate glycine and transfer a one-carbon unit into folate one-carbon metabolism. GLDC mutations cause a rare recessive disease non-ketotic hyperglycinemia (NKH).
Brosnan, JT, Brosnan, ME, Copp, AJ, Greene, ND, Heales, S, Hutchin, T, Leung, KY, Pai, YJ, Prunty, H, Savery, D   +9 more
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Synthesis and viscosity behavior of poly(γ-p-biphenylmethyl-L-glutamate) in benzene/dichloroacetic acid mixtures, a comparison with poly(γ-benzyl-L-glutamate) [PDF]

, 1974
The synthesis of poly(γ-p-biphenylmethyl-L-glutamate), PBPLG, (poly{L-imino-1-[2-(4-biphenylylmethoxycarbonyl)ethyl]-2-oxoethylene}), (1d) is described. The viscosity behavior of this polymer in benzene/dichloroacetic acid mixtures (c=0,2.10 -3 - 1,4.10 -
Bantjes, Adriaan, Feijen, Jan, Groot, Klaas de, Sederel, Wim L., Visser, Anthonie C. de   +4 more
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Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor [PDF]

The Journal of Physical Chemistry B, 2017
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is transmitted to the transmembrane region, opening the ...
Alvin Yu, Alvin Yu, Albert Y. Lau, Albert Y. Lau   +3 more
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Glutamate, Glutamate Receptors, and Downstream Signaling Pathways [PDF]

International Journal of Biological Sciences, 2013
Glutamate is a nonessential amino acid, a major bioenergetic substrate for proliferating normal and neoplastic cells, and an excitatory neurotransmitter that is actively involved in biosynthetic, bioenergetic, metabolic, and oncogenic signaling pathways. Glutamate signaling activates a family of receptors consisting of metabotropic glutamate receptors (
Stacey S. Willard, Shahriar Koochekpour
openaire   +3 more sources

Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. [PDF]

, 2019
Fam20C is a secreted protein kinase mutated in Raine syndrome, a human skeletal disorder. In vertebrates, bone and enamel proteins are major Fam20C substrates.
Adina Gerson-Gurwitz, Arribere, Arshad Desai, Bahl, Bando, Bies, Brown, Byerly, Cancino, Carolyn A. Worby, Carrascal, Cui, Dhanya Cheerambathur, Erin J. Cram, Fradin, Frøkjaer-Jensen, Gerald, Ghazarian, Gibson, Gorelik, Green, Ishikawa, Jack E. Dixon, Jeff Bouffard, Johnson, Kamath, Karen Oegema, Kian-Yong Lee, Kim, Kimble, Koike, Koob, Kovacevic, Köppen, Leiser, Leiser, Levin, Lindberg, Mann, Manning, Minko, Mody, Nakamura, Paschinger, Petrella, Pollak, Pollard, Pulvirenti, Raine, Reinhart, Renat Khaliullin, Rolls, Salvi, Sievers, Simpson, Sreelatha, Tagliabracci, Tagliabracci, Tagliabracci, Takeuchi, Tseng, Vogel, Wang, Ward, Wen, Wewer, Xiao, Yue, Zhang, Zhou, Zhou   +70 more
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Transient expression in Nicotiana benthamiana for rapid functional analysis of genes involved in non-photochemical quenching and carotenoid biosynthesis. [PDF]

, 2016
Plants must switch rapidly between light harvesting and photoprotection in response to environmental fluctuations in light intensity. This switch can lead to losses in absorbed energy usage, as photoprotective energy dissipation mechanisms can take ...
Erickson, Erika, Leonelli, Lauriebeth, Lyska, Dagmar, Niyogi, Krishna K   +3 more
core   +1 more source