Results 51 to 60 of about 221,194 (241)
Glutamate neurocircuitry: theoretical underpinnings in schizophrenia
Frontiers in Pharmacology, 2012 The Dopamine Hypothesis of Schizophrenia is actively being challenged by the NMDA Receptor Hypofunctioning Hypothesis of Schizophrenia. The latter hypothesis may actually be the starting point in neuronal pathways that ultimately modifies dopamine ...
Thomas L Schwartz +3 more
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Biological Sources of Inflexibility in Brain and Behavior with Aging and Neurodegenerative Diseases
Frontiers in Systems Neuroscience, 2012 Almost unequivocally, aging and neurodegeneration lead to deficits in neural information processing. These declines are marked by increased neural noise that is associated with increased variability or inconsistency in behavioral patterns.
S. Lee eHong, George V. Rebec
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Surface grafting of poly (L-glutamates). 1. Synthesis and characterization
, 2001 The ring-opening polymerization of N-carboxyanhydrides (NCA) of γ-benzyl l-glutamate and γ-methyl l-glutamate from (γ-aminopropyl)triethoxysilane (APS) pretreated substrates such as silicon wafers and quartz slides was investigated.
R. H. Wieringa +7 more
semanticscholar +1 more source
MedComm, 2023 Genetic heterogeneity poses a challenge to research and clinical translation of autism spectrum disorder (ASD). In this study, we conducted a plasma proteomic and metabolomic study of children with ASD with and without risk genes (de novo mutation) and ...
Xiaoxiao Tang +11 more
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A role for oxytocin in the etiology and treatment of schizophrenia
Frontiers in Endocrinology, 2015 Schizophrenia is a chronic debilitating neuropsychiatric disorder estimated to affect 51 million people worldwide. Several symptom domains characterize schizophrenia, including negative symptoms, such as social withdrawal and anhedonia, cognitive ...
Megan Elizabeth Rich +1 more
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Surface grafting of poly(L-glutamates). 2. Helix orientation
, 2001 In this paper the average helix orientation of surface-grafted poly(γ-benzyl l-glutamate) (PBLG), poly(γ-methyl l-glutamate) (PMLG), and poly(γ-methyl l-glutamate)-co-(γ-n-stearyl l-glutamate) (PMLGSLG 70/30) was investigated by means of FT-IR ...
R. H. Wieringa +5 more
semanticscholar +1 more source
Biotechnology & Biotechnological Equipment, 2019 A strain of Microbacterium kitamiense capable of decomposing cellulose was obtained from the soil of Shigatse region in Tibet. Low temperature and cellulase gene MkCel5 was cloned and sequenced.
Yuanyuan Li +4 more
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QM/MM study of the stereospecific proton exchange of glutathiohydroxyacetone by glyoxalase I
Results in Chemistry, 2019 We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (
Sonia Jafari, Ulf Ryde, Mehdi Irani
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Magnetic resonance imaging in studying schizophrenia, negative symptoms and the glutamate system
Frontiers in Psychiatry, 2014 Schizophrenia is characterized by positive, negative and cognitive symptoms. While positive symptoms occur periodically during psychotic exacerbations, negative and cognitive symptoms often emerge before the first psychotic episode and persist with low ...
Oliver eGruber +2 more
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What does the mediodorsal thalamus do?
Frontiers in Systems Neuroscience, 2013 Dense amnesia can result from damage to the medial diencephalon in humans and in animals. In humans this damage is diffuse and can include the mediodorsal nuclei of the thalamus.
Anna S Mitchell, Subhojit eChakraborty
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