Results 121 to 130 of about 20,010 (192)

Isolation and identification of actinomycetes for production of novel extracellular glutaminase free L-asparaginase

, 2015
786-793Over the recent years glutaminase free L-asparaginase has gained more importance due to better therapeutic properties for treatment of acute lymphoblastic leukemia. Actinomycetes are known for L-asparaginase activity.
Saxena, Akansha, Kango, Naveen, Upadhyay, Ramraj   +2 more
core  

Using combined ROC curves to improve the diagnostic usefulness of glutaminase, prostaglandins, and 8-isoprostane as biomarkers of autism spectrum disorders;Role in the Glu-GABA-Gln cycle. [PDF]

BMC Neurosci
El-Ansary A, Alfawaz HA, Alhakbany M, Bhat RS, Bjørklund G, Al-Ayadhi LY.   +5 more
europepmc   +1 more source

L-asparaginase by filamentous fungi and yeasts from lichens and soils across maritime Antarctic islands. [PDF]

Extremophiles
da Silva AV, Ferro BEF, Medeiros VDV, Dos Santos VC, da Silva MNP, Dos Santos Duarte CK, de Queiroz AC, Moreira MSA, Rosa LH, Duarte AWF.   +9 more
europepmc   +1 more source

Structure and enzymology of glutaminase S482C and H461L variants associated with excess brain glutamate and neurological disease. [PDF]

J Biol Chem
Crane CS, McIssac TK, Milano SK, Cerione RA, Ulrich SM.   +4 more
europepmc   +1 more source

Novel glutaminase-free l-asparaginase from <i>Leuconostoc mesenteroides</i> BN1: biochemical properties, molecular dynamics, and anticancer activity. [PDF]

RSC Adv
Charoenwongpaiboon T, Wangpaiboon K, Srichompoo Y, Septham P, Klaihmon P, Khampang S, Issaragrisil S, Lorthongpanich C.   +7 more
europepmc   +1 more source

Optimization of culture conditions for production of L-glutaminase enzyme from Klebsiella pneumoniae [PDF]

The main objective of this study was to investigate the production and activity of glutaminase by some clinical bacterial species. Two marine specimens, saltwater and sediment gathered from the Red Sea coast of Hurghada, Egypt, yielded 100 marine ...
Ibrahim, Asmaa E.M., Elariny, Eman. Y.T., Abdel-Hafez, Lina J.M.   +2 more
core  

Exploiting Metabolic Vulnerabilities in Acute Myeloid Leukemia: Rationale and Evidence for Combining Metabolic Modulators with Conventional Chemotherapy. [PDF]

Pharmaceuticals (Basel)
Shams UA, Inayat F, Zeb MA, Maryam, Shams S, Ullah MJ, Jiménez-Morales S.   +6 more
europepmc   +1 more source

GLUTAMINASE FREE L-ASPARAGINASE PRODUCING ENDOPHYTES FROM MANGROVES

, 2016
Objective: To screen endophytes isolated from mangroves for their potential to produce glutaminase free L-asparaginase .Methods: Endophytes were isolated from leaves and stems of three mangrove plants using surface sterilization technique followed by ...
G, Salini
core  

Lysine-Targeting Covalent Inhibition of Glutaminase Using Cyanopyrimidines. [PDF]

JACS Au
Xiao X, Okuno H, Inoue S, Zenmyo N, Matsumoto Y, Mishiro-Sato E, Kano K, Yoshimune K, Uchinomiya S, Ojida A.   +9 more
europepmc   +1 more source

Proteomic and Functional Profiling of Trichoderma reesei, Pichia guilliermondii, and Hericium erinaceus. [PDF]

J Agric Food Chem
Ahmed T, Juhász A, Bose U, Shiferaw Terefe N, Chan LY, Craik DJ, Colgrave ML.   +6 more
europepmc   +1 more source