Results 101 to 110 of about 19,538 (222)

Root Order Dependent Changes in Fine‐Root Substrate and Soil Environment Regulate Soil Organic Nitrogen Fractions Under Acid Rain and Nitrogen Deposition

Land Degradation &Development, Volume 37, Issue 14, Page 10464-10478, 30 August 2026.
ABSTRACT Acid rain and nitrogen deposition are important environmental stressors affecting soil nitrogen cycling in subtropical forests, whereas fine‐root decomposition represents a major pathway for soil organic nitrogen (SON) input and transformation.
Xiongfei Zhang, Xingyu Zhang, Jinchi Zhang, Jialei Ren, Chong Li, Hui Nie, Jingyi Zeng, Xuanran Yu, Jie Lin, Tingyu Sun, Xin Liu   +10 more
wiley   +1 more source

Dual targeting of EGFR and glutaminase in lung cancer

Molecular & Cellular Oncology, 2018
We have recently demonstrated that targeted inhibition of epidermal growth factor receptor (EGFR) signaling and glutaminase led to metabolic crisis in EGFR mutant lung adenocarcinomas and significant tumor regression in mouse xenograft models.
Milica Momcilovic, David B. Shackelford
doaj   +1 more source

Glutamine addiction: an Achilles heel in esophageal cancers with dysregulation of CDK4/6

Molecular & Cellular Oncology, 2019
Understanding and overcoming resistance to cyclin-dependent kinase 4/6 (CDK4/6) inhibitors will be challenging. Recent work reveals that dysregulation of F-Box Protein 4 (FBXO4)-Cyclin D1 axis leads to mitochondrial dysfunction and drives glutamine ...
Shuo Qie, J. Alan Diehl
doaj   +1 more source

Optimization of culture conditions for production of L-glutaminase enzyme from Klebsiella pneumoniae [PDF]

The main objective of this study was to investigate the production and activity of glutaminase by some clinical bacterial species. Two marine specimens, saltwater and sediment gathered from the Red Sea coast of Hurghada, Egypt, yielded 100 marine ...
Ibrahim, Asmaa E.M., Elariny, Eman. Y.T., Abdel-Hafez, Lina J.M.   +2 more
core   +1 more source

An Overview of Asparaginase Enzyme Features: An Anticancer Enzyme with High Potency

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introduction: One of the important findings in the pharmaceutical and medical industry is the use of the asparaginazase enzyme as an anticancer drug. The asparaginase enzyme, hydrolyzing the amino acid of asparagine, reduces this amino acid in the blood ...
Gholam Hossein Ebrahimipour, Mahtab Ghorban Movahed   +1 more
doaj  

Safety evaluation of the food enzyme glutaminase from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT

EFSA Journal
The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐GT by Amano Enzyme Inc.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Magdalena Andryszkiewicz, Daniele Cavanna, Yi Liu, Simone Lunardi, Elsa Nielsen, Karin Norby, Giulio diPiazza, Yrjö Roos, Andrew Chesson   +26 more
doaj   +1 more source

Alpha and Omega Classification of β-Lactamase/Transpeptidase-like Superfamily Proteins Based on the Comparison of Their Structural Catalytic Cores

Molecules
β-Lactamase/transpeptidase-like superfamily proteins are serine proteases that use the Ser–Lys catalytic dyad to carry out their biological functions. Here, we investigate the three known families of β-lactamase/transpeptidase-like superfamily proteins ...
Alexander I. Denesyuk, Konstantin Denessiouk, Mark S. Johnson, Vladimir N. Uversky   +3 more
doaj   +1 more source

Isolasi Dan Skrining Bakteri Endofit Penghasil Enzim L-Glutaminase Dari Mangrove (Sonneratia Alba) [PDF]

, 2017
Enzim L-glutaminase merupakan enzim yang mengkatalisis dan hidrolisis dari L-glutamin menjadi L-glutamat dan ammonia. Enzim ini dapat dimanfaatkan untuk kesehatan dan pangan.
Ningrum, Fifta Frizki Setya
core  

Neonatal Encephalopathy due to Glutaminase Deficiency in a Neonate

Clinical Case Reports
Identifying neurometabolic disorders that lead to neonatal encephalopathy is difficult, and access to exome sequencing is a significant advantage in developing countries.
Unnati Achanta, Shrinidhi Krishnan, Ashok Chandrasekaran, Robert Wilson S, Senthil Kumar Aiyappan, Subash Sundar   +5 more
doaj   +1 more source

ROLE OF CARBON SOURCE FOR THE PRODUCTION OF L-GLUTAMINASE FROM ASPERGILLUS ORYZAE

, 2014
Microbial glutaminases are more stable than plant and animal counterparts. In addition to it, they have also been detected in mammalian tissues where they are the major enzymes responsible for catabolic breakdown of glutamine. This study were taken up to
Siddalingeshwara, K G, Saroj, Yadava, PLNSN, Sunil Dutt, Naveen, M   +3 more
core   +1 more source