Results 101 to 110 of about 27,569 (215)
INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis.
Baguet, Tristan +12 more
core +1 more source
Ammonia toxicity: from head to toe? [PDF]
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
Glutamine and Glutaminase in Blood
Abstract A convenient and accurate procedure for the determination of glutaminase activity and glutamine in blood has been described. Kidney homogenate from rats made acidotic by feeding NH4CL was used as a glutaminase source and the Conway microdiffusion method was used to determine ammonia.
J, BRUTON, F L, IBER
openaire +2 more sources
Integrated schematic depicting the interplay between glioma stem‐like cells, telomere maintenance mechanisms, and metabolic reprogramming in shaping immune suppression and therapeutic resistance in glioblastoma . ABSTRACT Glioblastoma (GBM) is a highly aggressive, therapy‐resistant brain tumor with inevitable recurrence despite maximal multimodal ...
Ji‐Yong Sung, Kihwan Hwang
wiley +1 more source
Background and Objective: Celiac is a hereditary disease presented with chronic inflammation of small intestine. Several studies supposed a relationship between Celiac disease and Inflammatory Bowel Disease (IBD). Tissue trans-glutaminase antibody is one
Amiriani T +9 more
doaj
Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj +1 more source
This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu +5 more
wiley +1 more source
Epilepsy: Molecular Pathogenesis and Emerging Therapies
Progress has been made in the molecular pathogenesis of epilepsy, revealing multiple therapeutic targets. Recent advances in pharmacology, materials science, and surgical technique, coupled with progress in targeted therapy and disruptive epilepsy network technology, have led to the emergence of innovative strategies for epilepsy treatment.
Wanbin Huang +5 more
wiley +1 more source
Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon +1 more
core +3 more sources
ABSTRACT Enzymatic hydrolysis is used to produce protein hydrolysates from animal‐ and plant‐based sources, which are widely utilized in industry due to their nutritional, functional, and bioactive properties. However, these hydrolysates can exhibit unattractive sensory properties, such as off‐flavors or off‐odors, which limit their use in food ...
Tejaswini R. B. Ramakrishna +7 more
wiley +1 more source

