Results 101 to 110 of about 27,569 (215)

Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [18F]fluorophenylglutamine and [18F]fluorobiphenylglutamine

open access: yes, 2020
INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis.
Baguet, Tristan   +12 more
core   +1 more source

Ammonia toxicity: from head to toe? [PDF]

open access: yes, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan   +6 more
core   +1 more source

Glutamine and Glutaminase in Blood

open access: yesClinical Chemistry, 1956
Abstract A convenient and accurate procedure for the determination of glutaminase activity and glutamine in blood has been described. Kidney homogenate from rats made acidotic by feeding NH4CL was used as a glutaminase source and the Conway microdiffusion method was used to determine ammonia.
J, BRUTON, F L, IBER
openaire   +2 more sources

The Nexus of Stemness, Telomere Stability, and Metabolic Reprogramming in Glioblastoma: Foundations of Tumor Persistence and Targets for Intervention

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Integrated schematic depicting the interplay between glioma stem‐like cells, telomere maintenance mechanisms, and metabolic reprogramming in shaping immune suppression and therapeutic resistance in glioblastoma . ABSTRACT Glioblastoma (GBM) is a highly aggressive, therapy‐resistant brain tumor with inevitable recurrence despite maximal multimodal ...
Ji‐Yong Sung, Kihwan Hwang
wiley   +1 more source

Tissue trans-glutaminase antibody in Inflammatory Bowel Disease in Golestan province, Northern Iran (2005-08)

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2011
Background and Objective: Celiac is a hereditary disease presented with chronic inflammation of small intestine. Several studies supposed a relationship between Celiac disease and Inflammatory Bowel Disease (IBD). Tissue trans-glutaminase antibody is one
Amiriani T   +9 more
doaj  

Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points

open access: yesJHEP Reports
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj   +1 more source

Identification of Blood Pressure‐Associated Metabolites by Integrating Metabolomic and Genetic Analysis

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu   +5 more
wiley   +1 more source

Epilepsy: Molecular Pathogenesis and Emerging Therapies

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Progress has been made in the molecular pathogenesis of epilepsy, revealing multiple therapeutic targets. Recent advances in pharmacology, materials science, and surgical technique, coupled with progress in targeted therapy and disruptive epilepsy network technology, have led to the emergence of innovative strategies for epilepsy treatment.
Wanbin Huang   +5 more
wiley   +1 more source

Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]

open access: yes, 2018
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon   +1 more
core   +3 more sources

Factors Influencing Undesirable Sensory Properties in Protein Hydrolysates and Remediation Strategies for Food Applications

open access: yesJournal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT Enzymatic hydrolysis is used to produce protein hydrolysates from animal‐ and plant‐based sources, which are widely utilized in industry due to their nutritional, functional, and bioactive properties. However, these hydrolysates can exhibit unattractive sensory properties, such as off‐flavors or off‐odors, which limit their use in food ...
Tejaswini R. B. Ramakrishna   +7 more
wiley   +1 more source

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