Results 111 to 120 of about 19,538 (222)

Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points

JHEP Reports
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj   +1 more source

PRODUCTION AND OPTIMIZATION OF L-GLUTAMINASE ENZYME FROM Hypocrea jecorina PURE CULTURE

, 2013
L-Glutaminase (L-glutamine amidohydrolase, EC 3.5.1.2) is the important enzyme that catalyzes the deamination of L-glutamine to L-glutamic acid and ammonium ions.
Bülbül, Dilara, KARAKUŞ, Emine
core   +1 more source

Production of L-glutaminase and its optimization from a novel marine isolate Vibrio azureus JK-79

, 2016
L-Glutaminase is an amidohydrolase which is produced by a variety of micro-organisms including bacteria, yeast and fungi. It is currently used in the treatment of acute lymphoblastic leukemia (ALL) and human immunodeficiency virus (HIV).
Kiruthika, Jambulingam, Saraswathy, Nachimuthu   +1 more
core   +1 more source

Understanding the mechanism of activation and kinetic differences between the isoforms Kidney-type Glutaminase and Glutaminase C [PDF]

, 2018
Orientador: Andre Luis Berteli AmbrosioDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de BiologiaResumo: A produção de energia em células cancerosas é anormalmente dependente da glicólise aeróbica, resultando em aumento do consumo ...
Ferreira, Amanda Petrina Scotá, 1988-
core  

Role of dorsal root ganglion glutaminase in acute and chronic inflammatory pain

, 2013
Scope and methods of the study.The purpose of this study was to provide further evidence to support the concept that dorsal root ganglion (DRG) glutaminase, the synthetic enzyme for the neurotransmitter glutamate, is a potential target for analgesic ...
Zhang, Zijia
core  

LIVER GLUTAMINASES

Journal of Biological Chemistry, 1949
openaire   +2 more sources

Using combined ROC curves to improve the diagnostic usefulness of glutaminase, prostaglandins, and 8-isoprostane as biomarkers of autism spectrum disorders;Role in the Glu-GABA-Gln cycle. [PDF]

BMC Neurosci
El-Ansary A, Alfawaz HA, Alhakbany M, Bhat RS, Bjørklund G, Al-Ayadhi LY.   +5 more
europepmc   +1 more source

L-asparaginase by filamentous fungi and yeasts from lichens and soils across maritime Antarctic islands. [PDF]

Extremophiles
da Silva AV, Ferro BEF, Medeiros VDV, Dos Santos VC, da Silva MNP, Dos Santos Duarte CK, de Queiroz AC, Moreira MSA, Rosa LH, Duarte AWF.   +9 more
europepmc   +1 more source

Structure and enzymology of glutaminase S482C and H461L variants associated with excess brain glutamate and neurological disease. [PDF]

J Biol Chem
Crane CS, McIssac TK, Milano SK, Cerione RA, Ulrich SM.   +4 more
europepmc   +1 more source

The role of glutamine metabolism in the pathogenesis of idiopathic pulmonary fibrosis and its therapeutic potential. [PDF]

Front Oncol
Li J.
europepmc   +1 more source