Results 21 to 30 of about 472,248 (234)

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

open access: yeseLife, 2017
Many mammalian cancer cell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to support proliferation. However, some cell lines that depend on glutamine anaplerosis in culture rely less on glutamine catabolism to ...
Alexander Muir   +5 more
doaj   +1 more source

Effect of glutamine supplementation and replacement of tris-egg yolk based extender with defatted cow milk on spermatozoa quality after equilibration and thawing [PDF]

open access: yesVeterinary World, 2015
Aim: The present study was designed to evaluate the effect of supplementation of glutamine and replacement of Tris-egg yolk (TE) based buffer with defatted cow milk on the spermatozoa quality after equilibration and thawing. Materials and Methods: Semen
Vasundhara Dawra   +2 more
doaj   +1 more source

Metabolic Analysis of DFO-Resistant Huh7 Cells and Identification of Targets for Combination Therapy

open access: yesMetabolites, 2023
Hepatocellular carcinoma (HCC) is one of the most refractory cancers with a high rate of recurrence. Iron is an essential trace element, and iron chelation has garnered attention as a novel therapeutic strategy for cancer.
Koichi Fujisawa   +4 more
doaj   +1 more source

Enteral Glutamine Administration in Critically Ill Nonseptic Patients Does Not Trigger Arginine Synthesis

open access: yesJournal of Nutrition and Metabolism, 2016
Glutamine supplementation in specific groups of critically ill patients results in favourable clinical outcome. Enhancement of citrulline and arginine synthesis by glutamine could serve as a potential mechanism.
Mechteld A. R. Vermeulen   +7 more
doaj   +1 more source

MoGLN2 Is Important for Vegetative Growth, Conidiogenesis, Maintenance of Cell Wall Integrity and Pathogenesis of Magnaporthe oryzae

open access: yesJournal of Fungi, 2021
Glutamine is a non-essential amino acid that acts as a principal source of nitrogen and nucleic acid biosynthesis in living organisms. In Saccharomyces cerevisiae, glutamine synthetase catalyzes the synthesis of glutamine.
Osakina Aron   +7 more
doaj   +1 more source

Alloferon Affects the Chemosensitivity of Pancreatic Cancer by Regulating the Expression of SLC6A14

open access: yesBiomedicines, 2022
Pancreatic cancer (PCa), one of the most malignant solid tumors, has a high mortality rate. Although there have been many trials of chemotherapeutic drugs such as gemcitabine, the mortality rates remain significantly higher than for other types of cancer.
Hyejung Jo   +9 more
doaj   +1 more source

Effect of glutamine, glucose unhidrate and Moringa oleifera on blood lymphocytes in white mice (Rattus Novergicus) Wistar strain, following induction of a protein energy-deficient diet

open access: yesJournal of Public Health in Africa, 2022
The aim of this research was studied the influence of giving Glutamine, Glucose Unhydrate and Moringa oleifera the blood lymphocyte of white rat (Rattus novergicus) Strain Wistar that was induced with protein energy malnutrtion (PEM).
Septa Katmawanti   +9 more
doaj   +1 more source

Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Hepatic responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia was investigated. For this purpose, livers were perfused with a saturating concentration of 2 mM glycerol, 5 mM L-alanine or 5 mM L-glutamine as gluconeogenic ...
H.M. de Souza   +5 more
doaj   +1 more source

Glutamine metabolism in the proliferation of GS-expression pituitary tumor cells

open access: yesEndocrine Connections, 2020
Objective: Many cancer cells cannot survive without exogenous glutamine (Gln); however, cancer cells expressing glutamine synthetase (GS) do not have this restriction.
Jintao Hu   +6 more
doaj   +1 more source

Medical Nutrition Therapy in Short Bowel Syndrome and Food Interventions in Intestinal Adaptation

open access: yesAnadolu Hemşirelik ve Sağlık Bilimleri Dergisi, 2021
The 'normal' length of the small intestine ranges from 320 to 800 cm. short bowel syndrome is defined as the small bowel length less than 200 cm. Short bowel syndrome is a clinical manifestation that occurs mainly after anatomical and / or functional ...
Ebru KOPTAGEL, Hülya KAMARLI ALTUN
doaj   +1 more source

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