Results 21 to 30 of about 750,830 (294)

Distinct Roles of Perilipins in the Intramuscular Deposition of Lipids in Glutamine-Supplemented, Low-, and Normal-Birth-Weight Piglets

open access: yesFrontiers in Veterinary Science, 2021
Piglets with low birth weight (LBW) usually have reduced muscle mass and increased lipid deposition compared with their normal-birth-weight (NBW) littermates.
Yaolu Zhao   +6 more
doaj   +1 more source

Astrocyte glutamine synthetase : pivotal in health and disease [PDF]

open access: yes, 2013
The multifunctional properties of astrocytes signify their importance in brain physiology and neurological function. In addition to defining the brain architecture, astrocytes are primary elements of brain ion, pH and neurotransmitter homoeostasis.
Parpura, Vladimir   +2 more
core   +1 more source

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

open access: yeseLife, 2017
Many mammalian cancer cell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to support proliferation. However, some cell lines that depend on glutamine anaplerosis in culture rely less on glutamine catabolism to ...
Alexander Muir   +5 more
doaj   +1 more source

Radiosynthesis, in vitro and preliminary in vivo evaluation of the novel glutamine derived PET tracers [18F]fluorophenylglutamine and [18F]fluorobiphenylglutamine

open access: yes, 2020
INTRODUCTION: Glucose has been deemed the driving force of tumor growth for decades. However, research has shown that several tumors metabolically shift towards glutaminolysis.
Baguet, Tristan   +12 more
core   +1 more source

The Fusion Activity of HIV-1 gp41 Depends on Interhelical Interactions [PDF]

open access: yes, 2005
Infection by human immunodeficiency virus type I requires the fusogenic activity of gp41, the transmembrane subunit of the viral envelope protein. Crystallographic studies have revealed that fusion-active gp41 is a "trimer-of-hairpins" in which three ...
Chan, David C., Suntoke, Tara R.
core   +1 more source

p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake

open access: yesCell Reports, 2019
Summary: Cancer cells heavily depend on the amino acid glutamine to meet the demands associated with growth and proliferation. Due to the rapid consumption of glutamine, cancer cells frequently undergo glutamine starvation in vivo.
Xazmin H. Lowman   +6 more
doaj   +1 more source

An Intrinsic Alkalization Circuit Turns on mntP Riboswitch under Manganese Stress in Escherichia coli

open access: yesMicrobiology Spectrum, 2022
The trace metal manganese in excess affects iron-sulfur cluster and heme-protein biogenesis, eliciting cellular toxicity. The manganese efflux protein MntP is crucial to evading manganese toxicity in bacteria.
Arunima Kalita   +4 more
doaj   +1 more source

Low myo-inositol and high glutamine levels in brain are associated with neuropsychological deterioration after induced hyperammonemia [PDF]

open access: yes, 2004
The neuropsychological effect of hyperammonemia is variable. This study tests the hypothesis that the effect of ammonia on the neuropsychological function in patients with cirrhosis is determined by the ability of the brain to buffer ammonia-induced ...
Balata, S   +8 more
core   +1 more source

Differentiation Between Ripening Stages of Iberian Dry-Cured Ham According to the Free Amino Acids Content [PDF]

open access: yes, 2020
In this paper, the differentiation of three ripening stages, postsalting, drying, and cellar, of Iberian dry-cured ham has been carried out according to their free amino acids contents. Eighteen L-amino acids, alanine, 2-aminobutanoic acid, aspartic acid,
Alcázar Rueda, Ángela   +3 more
core   +1 more source

Gut mucosal and plasma concentrations of glutamine: a comparison between two enriched enteral feeding solutions in critically ill patients

open access: yesNutrition Journal, 2003
Background Addition of glutamine to enteral nutrition formulas is consistently associated with a significant decrease in septic morbidity in critically ill patients, possibly related to the attenuation of gut dysfunction.
Vincent Jean-Louis   +4 more
doaj   +1 more source

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