Results 51 to 60 of about 760,519 (335)

Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Hepatic responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia was investigated. For this purpose, livers were perfused with a saturating concentration of 2 mM glycerol, 5 mM L-alanine or 5 mM L-glutamine as gluconeogenic ...
H.M. de Souza   +5 more
doaj   +1 more source

Glutamine metabolism in the proliferation of GS-expression pituitary tumor cells

open access: yesEndocrine Connections, 2020
Objective: Many cancer cells cannot survive without exogenous glutamine (Gln); however, cancer cells expressing glutamine synthetase (GS) do not have this restriction.
Jintao Hu   +6 more
doaj   +1 more source

Medical Nutrition Therapy in Short Bowel Syndrome and Food Interventions in Intestinal Adaptation

open access: yesAnadolu Hemşirelik ve Sağlık Bilimleri Dergisi, 2021
The 'normal' length of the small intestine ranges from 320 to 800 cm. short bowel syndrome is defined as the small bowel length less than 200 cm. Short bowel syndrome is a clinical manifestation that occurs mainly after anatomical and / or functional ...
Ebru KOPTAGEL, Hülya KAMARLI ALTUN
doaj   +1 more source

Reduced glutamine synthetase activity alters the fecundity of female Bactrocera dorsalis (Hendel) [PDF]

open access: yes, 2019
Glutamine synthetase (GS) is a key enzyme in glutamine synthesis and is associated with multiple physiological processes in insects, such as embryonic development, heat shock response, and fecundity regulation.
Smagghe, Guy   +5 more
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

4-Hydroxyphenylpyruvate Dioxygenase-Like Protein Promotes Pancreatic Cancer Cell Progression and Is Associated With Glutamine-Mediated Redox Balance

open access: yesFrontiers in Oncology, 2021
Tumor cells develop a series of metabolic reprogramming mechanisms to meet the metabolic needs for tumor progression. As metabolic hubs in cells, mitochondria play a significant role in this process, including energy production, biosynthesis, and redox ...
Xianglai Ye   +33 more
doaj   +1 more source

Effect of the nitrogen source on glutamine and alanine biosynthesis in Neurospora crassa. An in vivo 15N nuclear magnetic resonance study [PDF]

open access: yes, 1982
The influences of different nitrogen sources on the relative rates of biosynthesis of glutamine and alanine have been studied by 15N nuclear magnetic resonance spectroscopy of intact Neurospora crassa mycelia suspensions.
Kanamori, Keiko   +3 more
core  

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Possibility of medicinal correction of disorders in metabolic cycle of neurotoxic transmitter glutamate in retina with neurotropic drugs during experimental glaucoma

open access: yesPatologìâ, 2012
Adult rabbits with experimental glaucoma were used in this study. We studied glutamate and glutamine levels and glutamine synthetase, glutamate oxidase and glutaminase activity in the eye tissue during glaucoma process.
V. M. Serdyuk
doaj   +1 more source

Glutamine Cooperatively Upregulates Lipopolysaccharide-Induced Nitric Oxide Production in BV2 Microglial Cells through the ERK and Nrf-2/HO-1 Signaling Pathway

open access: yesAntioxidants, 2020
Glutamine (Gln) is a nonessential α-amino acid for protein biosynthesis. However, the mechanism through which Gln regulates NO production in microglial cells is still unclear.
Rajapaksha Gedara Prasad Tharanga Jayasooriya   +4 more
doaj   +1 more source

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