Results 51 to 60 of about 750,830 (294)

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Glutamine supplementation to prevent morbidity and mortality in preterm infants [PDF]

, 2016
BACKGROUND: Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Evidence exists that glutamine supplementation improves clinical outcomes in critically ill adults.
Brown, Jennifer Ve, McGuire, William, Moe-Byrne, Thirimon   +2 more
core   +1 more source

Glutamine supplementation of parenteral nutrition does not improve intestinal permeability, nitrogen balance, or outcome in newborns and infants undergoing digestive-tract surgery: results from a double-blind, randomized, controlled trial [PDF]

, 2005
OBJECTIVE: To assess the effect of isocaloric isonitrogenous parenteral glutamine supplementation on intestinal permeability and nitrogen loss in newborns and infants after major digestive-tract surgery.
Albers, M.J.I.J. (Marcel), Borsboom, G.J.J.M. (Gerard), Hazebroek, F.W.J. (Frans), Huijmans, J.G.M. (Jan), Mourik, M., Rietveld, T. (Trinet), Steyerberg, E.W. (Ewout), Tibboel, D. (Dick)   +7 more
core   +8 more sources

Possibility of medicinal correction of disorders in metabolic cycle of neurotoxic transmitter glutamate in retina with neurotropic drugs during experimental glaucoma

Patologìâ, 2012
Adult rabbits with experimental glaucoma were used in this study. We studied glutamate and glutamine levels and glutamine synthetase, glutamate oxidase and glutaminase activity in the eye tissue during glaucoma process.
V. M. Serdyuk
doaj   +1 more source

Glutamine Cooperatively Upregulates Lipopolysaccharide-Induced Nitric Oxide Production in BV2 Microglial Cells through the ERK and Nrf-2/HO-1 Signaling Pathway

Antioxidants, 2020
Glutamine (Gln) is a nonessential α-amino acid for protein biosynthesis. However, the mechanism through which Gln regulates NO production in microglial cells is still unclear.
Rajapaksha Gedara Prasad Tharanga Jayasooriya, Ilandarage Menu Neelaka Molagoda, Matharage Gayani Dilshara, Yung Hyun Choi, Gi-Young Kim   +4 more
doaj   +1 more source

4-Hydroxyphenylpyruvate Dioxygenase-Like Protein Promotes Pancreatic Cancer Cell Progression and Is Associated With Glutamine-Mediated Redox Balance

Frontiers in Oncology, 2021
Tumor cells develop a series of metabolic reprogramming mechanisms to meet the metabolic needs for tumor progression. As metabolic hubs in cells, mitochondria play a significant role in this process, including energy production, biosynthesis, and redox ...
Xianglai Ye, Xianglai Ye, Xianglai Ye, Xiujuan Wei, Xiujuan Wei, Xiujuan Wei, Jing Liao, Jing Liao, Jing Liao, Peipei Chen, Peipei Chen, Peipei Chen, Xueyun Li, Xueyun Li, Xueyun Li, Yulong Chen, Yulong Chen, Yulong Chen, Yue Yang, Yue Yang, Yue Yang, Qiongya Zhao, Hongwei Sun, Liming Pan, Guorong Chen, Xujun He, Jianxin Lyu, Jianxin Lyu, Jianxin Lyu, Jianxin Lyu, Jianxin Lyu, Hezhi Fang, Hezhi Fang, Hezhi Fang   +33 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Glutamine: A novel approach to chemotherapy-induced toxicity

Indian Journal of Medical and Paediatric Oncology, 2012
Treatment of cancer is associated with short- and long-term side-effects. Cancer produces a state of glutamine deficiency, which is further aggravated by toxic effects of chemotherapeutic agents leading to increased tolerance of tumor to chemotherapy as ...
Kumar Gaurav, R K Goel, Mridula Shukla, Manoj Pandey   +3 more
doaj   +1 more source

A metabolic shift toward glycolysis enables cancer cells to maintain survival upon concomitant glutamine deprivation and V-ATPase inhibition

Frontiers in Nutrition, 2023
It is widely known that most cancer cells display an increased reliance on glutaminolysis to sustain proliferation and survival. Combining glutamine deprivation with additional anti-cancer therapies is an intensively investigated approach to increase ...
Florian Lengauer, Franz Geisslinger, Antje Gabriel, Karin von Schwarzenberg, Angelika M. Vollmar, Karin Bartel   +5 more
doaj   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source