Results 71 to 80 of about 1,091,861 (290)

Glutamine Metabolism and Its Role in Immunity, a Comprehensive Review

Animals, 2020
In the body of an animal, glutamine is a plentiful and very useful amino acid. Glutamine consumption in the body of animals in normal or disease conditions is the same or higher than the glucose.
Ali Mujtaba Shah, Zhisheng Wang, Jian Ma   +2 more
doaj   +1 more source

Glutamine Starvation Affects Cell Cycle, Oxidative Homeostasis and Metabolism in Colorectal Cancer Cells

Antioxidants, 2023
Cancer cells adjust their metabolism to meet energy demands. In particular, glutamine addiction represents a distinctive feature of several types of tumors, including colorectal cancer.
Martina Spada, Cristina Piras, Giulia Diana, Vera Piera Leoni, Daniela Virginia Frau, Gabriele Serreli, Gabriella Simbula, Roberto Loi, Antonio Noto, Federica Murgia, Paola Caria, Luigi Atzori   +11 more
doaj   +1 more source

Glutamine metabolism in advanced age [PDF]

Nutrition Reviews, 2016
Glutamine, reviewed extensively in the last century, is a key substrate for the splanchnic bed in the whole body and is a nutrient of particular interest in gastrointestinal research. A marked decrease in the plasma glutamine concentration has recently been observed in neonates and adults during acute illness and stress.
openaire   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Single-cell transcriptomic data reveal the cellular heterogeneity of glutamine metabolism in gastric premalignant lesions and early gastric cancer

Acta Biochimica et Biophysica Sinica
Glutamine metabolism is a hallmark of cancer metabolism. This study aims to perform a comprehensive and systematic single-cell profile of glutamine metabolism in premalignant and malignant gastric lesions.
Ni Qingfeng, Yu Jiawei, Niu Yuanjie, Han Zhenwei, Hu Boyang, Wang Yang, Zhu Jianwei   +6 more
doaj   +1 more source

Glutamine metabolism in tumor metastasis: Genes, mechanisms and the therapeutic targets

Heliyon, 2023
Cancer cells frequently change their metabolism from aerobic glycolysis to lipid metabolism and amino acid metabolism to adapt to the malignant biological behaviours of infinite proliferation and distant metastasis.
Xugang Zhong, Zeju He, Li Yin, Yong Fan, Yu Tong, Yao Kang, Qing Bi   +6 more
doaj   +1 more source

Glutamine Metabolism in Higher Plants

, 1981
Publisher Summary This chapter discusses metabolism and the role of glutamine in the flow of nitrogen. Under certain conditions, all the nitrogen assimilated by bacteria could pass through glutamine. The plant enzyme, in common with that from other sources, exhibits a number of activities that have been the basis of a number of different assays.
Miflin, B. J., Wallsgrove, R. M., Lea, P. J.   +2 more
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An introduction to glutamine metabolism

, 2017
© 2017 by Taylor & Francis Group, LLC. Hlaziwetz and Habermann rst described glutamine as a molecule with biologically important properties in 1873. They suggested that the presence of ammonia (as NH4+), detected following hydrolysis of proteins, arose
Cruzat, Vinicius, Vinicius Fernandes Cruzat, Marino, Luise V., Calder, Philip C., Philip Newsholme, Newsholme, P.   +5 more
core   +2 more sources

Asparagine and Glutamine Metabolism in Chicks

Poultry Science, 1984
In a series of four experiments, asparaginase and glutaminase activity was measured in liver and kidney tissue of 7- to 19-day-old male broiler chicks. In Experiment 1, chicks were fed purified amino acid diets with 14.8 and 44.6% protein equivalents (PE) with 1, 3, or 5% added sodium bicarbonate.
Coon, C., BALLING, Rudi
openaire   +3 more sources