Results 51 to 60 of about 3,189 (173)

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4577-4598, July 2026.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Aging-dependent changes in rat heart mitochondrial glutaredoxins—Implications for redox regulation

Redox Biology, 2013
Clinical and animal studies have documented that hearts of the elderly are more susceptible to ischemia/reperfusion damage compared to young adults. Recently we found that aging-dependent increase in susceptibility of cardiomyocytes to apoptosis was ...
Xing-Huang Gao, Suparna Qanungo, Harish V. Pai, David W. Starke, Kelly M. Steller, Hisashi Fujioka, Edward J. Lesnefsky, Janos Kerner, Mariana G. Rosca, Charles L. Hoppel, John J. Mieyal   +10 more
doaj   +1 more source

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

Molecular Control of Redox Homoeostasis in Specifying the Cell Identity of Tapetal and Microsporocyte Cells in Rice

Rice, 2019
In flowering plants, male reproduction occurs within the male organ anther with a series of complex biological events including de novo specification of germinal cells and somatic cells, male meiosis, and pollen development and maturation.
Jing Yu, Dabing Zhang
doaj   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Comparison of structures among Saccharomyces cerevisiae Grxs proteins

Genes and Environment, 2018
Glutaredoxins (Grxs) comprise a group of glutathione (GSH)-dependent oxidoreductase enzymes that respond to oxidative stress and sustain redox homeostasis.
Mohnad Abdalla, Wafa Ali Eltayb, Aadil Yousif   +2 more
doaj   +1 more source

Effect of RNAi Targeting SeGrx1 on the Cytotoxicity and Insecticide Susceptibility of Camptothecin in Spodoptera exigua

Agriculture, 2022
Glutaredoxins (Grxs) are a class of small, heat-stable, acidic proteins which have been implied in various biological activities in cells, including the defense against oxidative stress induced by various biotic and abiotic factors.
Fulai Yang, Lan Zhang, Yanning Zhang, Liangang Mao, Lizhen Zhu, Xingang Liu, Hongyun Jiang   +6 more
doaj   +1 more source

Under the Cover of Darkness: A Transcriptomic Exploration of Clubroot During the Night

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Plasmodiophora brassicae (Phytomyxea, Rhizaria) is the etiological agent of clubroot disease, one of the most important diseases of Brassicaceae crops. Alteration of metabolism and hormone homeostasis leads to the formation of tumor‐like galls in the roots of affected plants.
Andrea Garvetto, Susann Auer, Freia Benade, Michaela Hittorf, Jutta Ludwig‐Müller, Sigrid Neuhauser   +5 more
wiley   +1 more source

Glutaredoxin is a direct target of oncogenic jun [PDF]

Oncogene, 1998
We have analysed differential gene expression in v-jun-transformed chicken embryo fibroblasts (CEF) compared to normal CEF by using the directional tag PCR subtraction method. From a first generation of putative Jun targets four clones were selected for study; they are upregulated in jun-transformed cells. Three of these clones showed homology to known
M E, Goller, J S, Iacovoni, P K, Vogt, U, Kruse   +3 more
openaire   +2 more sources

CC-type glutaredoxins mediate plant response and signaling under nitrate starvation in Arabidopsis

BMC Plant Biology, 2018
Background Nitrogen is an essential nutrient in plants. Despite the importance of nitrogen for plant growth and agricultural productivity, signal transduction pathways in response to nitrate starvation have not been fully elucidated in plants.
Ji-Yul Jung, Ji Hoon Ahn, Daniel P. Schachtman   +2 more
doaj   +1 more source