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AUT-M enterosorbent stabilizes glutathione system in vincristine-treated rats with dimethylhydrazine-induced colon cancer [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
Colorectal cancer is one of the leading causes of mortality in the world. The search for new methods of therapy for this disease that could correct the state of oxidative stress during the development of neoplasms is up to date.
O. I. Kachur   +4 more
doaj   +1 more source

Perturbations of Glutathione and Sphingosine Metabolites in Port Wine Birthmark Patient-Derived Induced Pluripotent Stem Cells

open access: yesMetabolites, 2023
Port Wine Birthmarks (PWBs) are a congenital vascular malformation on the skin, occurring in 1–3 per 1000 live births. We have recently generated PWB-derived induced pluripotent stem cells (iPSCs) as clinically relevant disease models.
Vi Nguyen   +9 more
doaj   +1 more source

Antioxidative Stress Metabolic Pathways in Moderately Active Individuals

open access: yesMetabolites, 2023
Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood.
Shamma Almuraikhy   +7 more
doaj   +1 more source

The Role of Glutathione in Selected Viral Diseases

open access: yesAntioxidants, 2023
During inflammatory processes, immunocompetent cells are exposed to substantial amounts of free radicals and toxic compounds. Glutathione is a cysteine-containing tripeptide that is an important and ubiquitous antioxidant molecule produced in human ...
Joanna Wróblewska   +6 more
doaj   +1 more source

On the Role of ROS and Glutathione in the Mode of Action Underlying Nrf2 Activation by the Hydroxyanthraquinone Purpurin

open access: yesAntioxidants, 2023
Purpurin is a major anthraquinone present in the roots of Rubia cordifolia (madder). Purpurin is known to activate Nrf2 (Nuclear transcription factor erythroid 2-related factor 2) EpRE (electrophile responsive element) mediated gene expression as a ...
Qiuhui Ren   +4 more
doaj   +1 more source

Targeting the Cysteine Redox Proteome in Parkinson’s Disease: The Role of Glutathione Precursors and Beyond

open access: yesAntioxidants, 2023
Encouraging recent data on the molecular pathways underlying aging have identified variants and expansions of genes associated with DNA replication and repair, telomere and stem cell maintenance, regulation of the redox microenvironment, and ...
Marcos A. Martinez-Banaclocha
doaj   +1 more source

Research progress of glutathione peroxidase family (GPX) in redoxidation

open access: yesFrontiers in Pharmacology, 2023
Maintaining the balance of a cell’s redox function is key to determining cell fate. In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost ...
Jun Pei   +3 more
semanticscholar   +1 more source

Exogenously Applied Cyclitols and Biosynthesized Silver Nanoparticles Affect the Soluble Carbohydrate Profiles of Wheat (Triticum aestivum L.) Seedling

open access: yesPlants, 2023
Cyclitols, such as myo-inositol and its isomers and methyl derivatives (i.e., d-chiro-inositol and d-pinitol (3-O-methyl-chiro-inositol)), are classified as osmolytes and osmoprotectants and are significantly involved in plant responses to abiotic ...
Lesław B. Lahuta   +7 more
doaj   +1 more source

Glutathione-Related Enzymes and Proteins: A Review

open access: yesMolecules, 2023
The tripeptide glutathione is found in all eukaryotic cells, and due to the compartmentalization of biochemical processes, its synthesis takes place exclusively in the cytosol.
J. Vašková   +3 more
semanticscholar   +1 more source

Palladium Nanoparticles Grafted onto Phytochemical Functionalized Biochar: A Sustainable Nanozyme for Colorimetric Sensing of Glucose and Glutathione

open access: yesMolecules, 2023
The devising and development of numerous enzyme mimics, particularly nanoparticles and nanomaterials (nanozymes), have been sparked by the inherent limitations imposed by natural enzymes.
Aakhila Banu   +4 more
doaj   +1 more source

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