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Research progress of glutathione peroxidase family (GPX) in redoxidation

open access: yesFrontiers in Pharmacology, 2023
Maintaining the balance of a cell’s redox function is key to determining cell fate. In the critical redox system of mammalian cells, glutathione peroxidase (GPX) is the most prominent family of proteins with a multifaceted function that affects almost ...
Jun Pei   +3 more
semanticscholar   +1 more source

Changing Perspectives from Oxidative Stress to Redox Signaling—Extracellular Redox Control in Translational Medicine

open access: yesAntioxidants, 2022
Extensive research has changed the understanding of oxidative stress that has been linked to every major disease. Today we distinguish oxidative eu- and distress, acknowledging that redox modifications are crucial for signal transduction in the form of ...
Paola Loreto Palacio   +3 more
doaj   +1 more source

Glutathione-Related Enzymes and Proteins: A Review

open access: yesMolecules, 2023
The tripeptide glutathione is found in all eukaryotic cells, and due to the compartmentalization of biochemical processes, its synthesis takes place exclusively in the cytosol.
J. Vašková   +3 more
semanticscholar   +1 more source

5-Methyltetrahydrofolate Attenuates Oxidative Stress and Improves Kidney Function in Acute Kidney Injury through Activation of Nrf2 and Antioxidant Defense

open access: yesAntioxidants, 2022
Oxidative stress is a major mediator of adverse outcomes in acute kidney injury (AKI). Deficiency of micronutrients, such as folate, is common in AKI. Our previous study reported that AKI impaired kidney reabsorption of folate and decreased plasma folate
Charith U. B. Wijerathne   +3 more
doaj   +1 more source

Metabolomic Analysis of Carbohydrate and Amino Acid Changes Induced by Hypoxia in Naked Mole-Rat Brain and Liver

open access: yesMetabolites, 2022
Hypoxia poses a major physiological challenge for mammals and has significant impacts on cellular and systemic metabolism. As with many other small rodents, naked mole-rats (NMRs; Heterocephalus glaber), who are among the most hypoxia-tolerant mammals ...
Hang Cheng   +5 more
doaj   +1 more source

Liposomes as Carriers for the Delivery of Efavirenz in Combination with Glutathione—An Approach to Combat Opportunistic Infections

open access: yesApplied Sciences, 2022
Human immunodeficiency virus (HIV)-infected individuals display an enhanced production of reactive oxygen species (ROS). This reduction of antioxidant capacity in host tissues has been related to the decrease in total levels of ROS scavengers such as ...
Vanaja Kenchappa   +3 more
doaj   +1 more source

Oxidative Stress in Relation to Aging and Exercise

open access: yesEncyclopedia, 2022
Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage.
Dimphna Verhaegen   +3 more
doaj   +1 more source

Expression of Heterologous OsDHAR Gene Improves Glutathione (GSH)-Dependent Antioxidant System and Maintenance of Cellular Redox Status in Synechococcus elongatus PCC 7942. [PDF]

open access: yes, 2020
An excess of reactive oxygen species (ROS) can cause severe oxidative damage to cellular components in photosynthetic cells. Antioxidant systems, such as the glutathione (GSH) pools, regulate redox status in cells to guard against such damage ...
Beld, Joris   +9 more
core   +2 more sources

A reverse chemical ecology approach to explore wood natural durability [PDF]

open access: yes, 2020
The natural durability of wood species, defined as their inherent resistance to wood‐destroying agents, is a complex phenomenon depending on many biotic and abiotic factors.
Beauchène J.   +11 more
core   +1 more source

Effect of atrazine on glutathione levels, glutathione s-transferase and glutathione reductase activities in pea and wheat plants

open access: yesPlant Protection Science, 2004
Changes were studied in the endogenous level of glutathione (total and oxidised), and in the amount of free thiol groups as caused by the herbicide atrazine on two species of plants with different sensitivity to it.
Lyuba P.-E. Miteva   +3 more
doaj   +1 more source

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