Results 261 to 270 of about 618,316 (340)

NAT10 Increases Lysosomal Acidification to Promote Esophageal Cancer Metastasis via ac4C Acetylation of ATP6V0E1 mRNA

open access: yesAdvanced Science, EarlyView.
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan   +23 more
wiley   +1 more source

TaPPR13, a Pentatricopeptide Repeat Protein Gene Activated by TaBZR2, Confers Drought Stress Tolerance by Enhancing the Antioxidant Defense System and Promoting Retrograde Signaling in Wheat (Triticum aestivum)

open access: yesAdvanced Science, EarlyView.
TaPPR13, a PPR protein family gene in wheat is activated by TaBZR2 to enhance drought stress tolerance and photosynthetic capacity. It achieves this by interacting with TaAOR1 and TaSIG5 to improve antioxidant defense and regulate chloroplast gene expression. Abstract The wheat (Triticum aestivum) brassinazole‐resistant 2 (TaBZR2) gene is identified as
Ze‐Hao Hou   +20 more
wiley   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu   +9 more
wiley   +1 more source

Dynamic and Stable Core Microbiota Assist Plants in Enriching Selenium and Reducing Cadmium Absorption. [PDF]

open access: yesAdv Sci (Weinh)
Lei Z   +16 more
europepmc   +1 more source

Manipulating Liquid‐Liquid Interphase Solute Diffusion for the Construction of Non‐Symmetric Metal‐Quinone Network Nanoarchitectonics and Nano‐Motorization

open access: yesAdvanced Science, EarlyView.
Non‐symmetric metal‐quinone network (MQN) nanoarchitectonics with controllable morphology and size are constructed by manipulating interphase solute diffusion during the nanoprecipitation process. Self‐propelled nanomotors developed from non‐symmetric MQN nanoarchitectonics exhibit chemotactic autonomous motion toward overexpressed H2O2 in tumor ...
Wenzhe Xu   +6 more
wiley   +1 more source

Effects of bortezomib on intracellular antioxidant and apoptosis in HepG2cells. [PDF]

open access: yesPeerJ
Świderska-Kołacz G   +8 more
europepmc   +1 more source

Accelerating Sono‐Piezoelectric Charge Transport for Antibacterial Therapy and Bone Regeneration by Metal‐Deficient TiO2 Spin‐Polarization Effect

open access: yesAdvanced Science, EarlyView.
The deficient TiO2 (DTO) and Barium titanate (BTO) heterojunction treats osteomyelitis through SDT. The spin‐polarization effect induced by the unpaired spin electrons in Ti atoms can expedite the transfer of ultrasonic piezoelectric charges in BTO, enhancing surface sonocatalytic efficiency.
Chaofeng Wang   +10 more
wiley   +1 more source

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