Results 161 to 170 of about 223,107 (283)

Structural and Functional Characterization of Camelus dromedarius Glutathione Transferase M1-1. [PDF]

Life (Basel), 2022
Perperopoulou F, Poudel N, Papageorgiou AC, Ataya FS, Labrou NE.   +4 more
europepmc   +1 more source

Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids. [PDF]

Front Mol Biosci, 2022
Sylvestre-Gonon E, Morette L, Viloria M, Mathiot S, Boutilliat A, Favier F, Rouhier N, Didierjean C, Hecker A.   +8 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Ligandability Assessment of Human Glutathione Transferase M1-1 Using Pesticides as Chemical Probes. [PDF]

Int J Mol Sci, 2022
Bodourian CS, Poudel N, Papageorgiou AC, Antoniadi M, Georgakis ND, Abe H, Labrou NE.   +6 more
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes. [PDF]

Molecules, 2021
Alqarni MH, Foudah AI, Muharram MM, Labrou NE.   +3 more
europepmc   +1 more source

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta‐Analysis

Journal of Applied Toxicology, EarlyView.
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Thiago Guedes Pinto, Vinícius Fialho do Nascimento, Giovanna Abreu Holanda Guerra, Wilton Mitsunari Takeshita, Raquel Alves Sales, Andrea Cristina de Moraes Malinverni, Luciana Lopes Guimaraes, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Structural insights into sigma class glutathione transferase from Taenia solium: Analysis and functional implications. [PDF]

PLoS Negl Trop Dis
Miranda-Blancas R, García-Gutiérrez P, Sánchez-Juárez C, Cardona-Echavarría MC, Flores-López R, Zubillaga RA, Rodríguez-Lima O, Sánchez-Pérez LC, Rudiño-Piñera E, Landa A.   +9 more
europepmc   +1 more source

The Interaction of the Flavonoid Fisetin with Human Glutathione Transferase A1-1. [PDF]

Metabolites, 2021
Alqarni MH, Foudah AI, Muharram MM, Labrou NE.   +3 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source