Results 161 to 170 of about 202,820 (240)

Glutathione Transferase Photoaffinity Labeling Displays GST Induction by Safeners and Pathogen Infection. [PDF]

open access: yesPlant Cell Physiol
Font Farre M   +8 more
europepmc   +1 more source

Imaging Ligand‐Receptor Interactions at Single‐Protein Resolution with DNA‐PAINT

open access: yesSmall Methods, EarlyView.
A labeling approach for small ligands in DNA‐PAINT super‐resolution microscopy preserving ligand functionality is demonstrated. This method enables the study of ligand‐receptor interactions at single‐protein resolution providing detailed insights into their spatial arrangement and interactions. Here, the interaction of the Epidermal Growth Factor (EGF)
Monique Honsa   +8 more
wiley   +1 more source

Spatiotemporal Interrogation of Single Spheroids Using Multiplexed Nanoplasmonic‐Fluorescence Imaging

open access: yesSmall Methods, EarlyView.
This work introduces a multiplexed imaging platform that integrates nanoplasmonic sensing with fluorescence microscopy for concomitant monitoring of extraspheroid secretions and intraspheroid features over extended periods with spatiotemporal resolution.
Saeid Ansaryan   +7 more
wiley   +1 more source

A generic cross‐seeding approach to protein crystallization

open access: yesJournal of Applied Crystallography, Volume 58, Issue 2, Page 383-391, April 2025.
A mixture integrating a wide variety of protein crystal fragments was used to obtain a new crystal structure of the human retinoblastoma binding protein 9.Obtaining diffraction‐quality crystals is often the rate‐limiting step during structure determination of biological macromolecules by X‐ray crystallography. To address this problem, we investigated a
Ido Caspy   +3 more
wiley   +1 more source

A Monocarbonyl Curcuminoid Derivative Inhibits the Activity of Human Glutathione Transferase A4-4 and Chemosensitizes Glioblastoma Cells to Temozolomide. [PDF]

open access: yesPharmaceuticals (Basel)
Tsouri S   +11 more
europepmc   +1 more source

An integrative strategy used by the aphid Uroleucon formosanum to counter host sesquiterpene lactone defense: Insights from combined genomic and transcriptomic analysis

open access: yesInsect Science, EarlyView.
We report the first high‐quality chromosome‐level genome assembly for the aphid Uroleucon formosanum, a serious pest that infests lettuce in eastern Asia. A combination of comparative genomic analyses and RNA‐seq transcriptome profiling suggests that U. formosanum employs integrative mechanisms to cope with host plant‐derived sesquiterpene lactone (STL)
Jing‐Bo Li   +3 more
wiley   +1 more source

A Short‐Read Amplicon Sequencing Protocol and Bioinformatic Pipeline for Ecological Surveillance of Dipteran Disease Vectors

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Vector control remains an important strategy worldwide to prevent human infection with pathogens transmitted by arthropods. Vector control strategies rely on accurate identification of vector taxa along with vector‐specific biological indicators such as feeding ecology, infection prevalence and insecticide resistance.
Raquel Lima‐Cordón   +18 more
wiley   +1 more source

Novel TORC1 inhibitor Ecl1 is regulated by phosphorylation in fission yeast

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Extender of chronological lifespan 1 (Ecl1), which inhibits the target of rapamycin complex 1 (TORC1), physically interacts with TORC1 subunits and is necessary for appropriate cellular responses to various stressors, such as starvation, in fission yeast. Several functions of Ecl1 are suppressed by Thr7 phosphorylation when nutrients are abundant.
Hokuto Ohtsuka   +10 more
wiley   +1 more source

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