MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen +4 more
wiley +1 more source
Biochemical and Structural Characterization of Chi-Class Glutathione Transferases: A Snapshot on the Glutathione Transferase Encoded by sll0067 Gene in the Cyanobacterium Synechocystis sp. Strain PCC 6803. [PDF]
Mocchetti E +10 more
europepmc +1 more source
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley +1 more source
Identification of glutathione transferase (GST P1) inhibitors via a high-throughput screening assay and implications as alternative treatment options for breast cancers. [PDF]
Pereira SAP +5 more
europepmc +1 more source
Characterization of Dog Glutathione Transferase P1-1, an Enzyme Relevant to Veterinary Medicine. [PDF]
Ismail A +3 more
europepmc +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Characterization of FosA13, a novel fosfomycin glutathione transferase identified in a <i>Morganella morganii</i> isolate from poultry. [PDF]
Zhang R +12 more
europepmc +1 more source
Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants. [PDF]
Guneidy RA +4 more
europepmc +1 more source
Co‐application of Bacillus strains TM22 and MCM61 suppressed Fusarium wilt of cotton. Seed biopriming with Bacillus strains performed better than soil drenching. TM22 + MCM61 improved vegetative and physiological aspects in cotton plants. TM22 + MCM61 enhanced the activity of defense enzymes and defense gene expression.
Tahir Mahmood +11 more
wiley +1 more source

