Cigarette Smoke Targets Glutaredoxin 1, Increasing S-Glutathionylation and Epithelial Cell Death
It is established that cigarette smoke causes irreversible oxidations in lung epithelial cells and can lead to their death. However, its impact on reversible and physiologically relevant redox-dependent protein modifications remains to be investigated ...
Kuipers, I. +17 more
core +1 more source
Redox-Responsive Protein Design: Design of a Small Protein Motif Dependent on Glutathionylation
Cysteine S-glutathionylation is a protein post-translational modification that promotes cellular responses to changes in oxidative conditions. The design of protein motifs that directly depend on defined changes to protein side chains provides new ...
Christina R. Forbes +5 more
core +1 more source
Glutathionylation assay with BIOGEE.
Glutathionylated actin was detected as described in Methods. Densitometric analysis of the obtained bands revealed that actin S-glutathionylation significantly increased in cells treated with CdCl2 with respect to CTR.
Marianna Ranieri (330759) +10 more
core +1 more source
Glyoxalase II, the second of 2 enzymes in the glyoxalase system, is a hydroxyacylglutathione hydrolase that catalyses the hydrolysis of S-d-lactoylglutathione to form d-lactic acid and glutathione, which is released from the active site.
Cianfruglia, L +21 more
core +1 more source
Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle [PDF]
We have shown previously that electrically induced tachycardia effectively produces myocardial preconditioning. Among other effects, tachycardia increases calcium release rates in microsomal fractions enriched in sarcoplasmic reticulum (SR) isolated from
Pedrozo Cibils, Zully +4 more
core
Reactive Oxygen Species-Induced Actin Glutathionylation Controls Actin Dynamics in Neutrophils
The regulation of actin dynamics is pivotal for cellular processes such as cell adhesion, migration, and phagocytosis and thus is crucial for neutrophils to fulfill their roles in innate immunity. Many factors have been implicated in signal-induced actin
Jia, Yonghui +13 more
core +1 more source
Metabolic Synthesis of Clickable Glutathione for Chemoselective Detection of Glutathionylation
Glutathionylation involves reversible protein cysteine modification that regulates the function of numerous proteins in response to redox stimuli, thereby altering cellular processes.
Kusal T. G. Samarasinghe (1761181) +3 more
core +1 more source
S-Glutathionylation in Arabipdosis Thaliana
Comunicaciones a ...
Echevarría-Zomeño, Sira +3 more
openaire +1 more source
Post-translational modifications of na+/K+-atpase subunits: regulatory mechanisms and functional implications. [PDF]
Tong J +5 more
europepmc +1 more source
Glutathione S-Transferase Omega 1 Promotes Macrophage Inflammation-Associated Coagulopathy in Sepsis by S-Glutathionylating ANXA5 to Enhance Its Ubiquitination. [PDF]
Peng J, Hu C, Fu X, Li S, Liu W, Peng J.
europepmc +1 more source

