Results 181 to 190 of about 1,992 (243)

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

Upcoming Treatments in Celiac Disease: From Luminal Enzymes to Oral Immune Tolerance. [PDF]

United European Gastroenterol J
Taavela J, Elli L, Bouma G, Tye-Din JA, Schuppan D, Lundin KEA, Schumann M.   +6 more
europepmc   +1 more source

The TG2/LRP1 Pathway for T Cell Activation by Post‐Translationally Modified Antigens

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Post‐translational modifications (PTMs) can generate neo‐epitopes, modified peptides that evade immune tolerance and trigger immune responses. This review focuses on the TG2/LRP1 pathway as a new paradigm for coupling the formation of post‐translationally modified peptides with their effective presentation as T‐cell antigens by dendritic cells.
Agnele Sylvia Sewa, Fu‐Chen Yang, Chaitan Khosla   +2 more
wiley   +1 more source

Potential Transfer of Toxic Gluten from Biodegradable Tableware to Gluten-Free Foods: Implications for Individuals with Gluten-Related Disorders. [PDF]

J Agric Food Chem
Sousa C, Heredia A, de Arcos L, Segura V, Ruiz-Carnicer Á, Comino I.   +5 more
europepmc   +1 more source

Citrullination and Deamidation in Type 1 Diabetes: Linking Beta Cell Stress to Neoantigen‐Driven Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Citrullination and deamidation are post‐translational modifications (PTMs) increasingly recognized as important contributors to neoepitope formation in type 1 diabetes (T1D). Under inflammatory and endoplasmic reticulum stress conditions, beta cells activate calcium‐dependent peptidylarginine deiminase and transglutaminase enzymes, leading to ...
Aïsha Callebaut, Ylke Bruggeman, Chantal Mathieu, Eddie A. James, Lut Overbergh   +4 more
wiley   +1 more source

Long-term health outcomes of people without celiac disease avoiding gluten consumption: a 25-year prospective cohort study. [PDF]

Eur J Clin Nutr
Salmela E, Kalle K, Lindfors K, Saavalainen P, Huhtala H, Kaukinen K, Taavela J.   +6 more
europepmc   +1 more source

Persisting Transglutaminase 6 Antibodies in Neurological Gluten-Related Disorders. [PDF]

Ann Neurol
Croall ID, Hadjivassiliou M, Sanders DS, Teh K, Biancardi AM, Trott N, Hoggard N.   +6 more
europepmc   +1 more source

Acute gluten-induced inflammatory response highlights CCL20 as a potential biomarker for celiac disease. [PDF]

Front Immunol
Gómez-Aguililla S, Farrais S, López-Palacios N, Arau B, Senosiain C, Infante-Menéndez J, Ruiz-Carnicer Á, Fernández-Bañares F, González-López N, Pujals M, Sousa C, Núñez C.   +11 more
europepmc   +1 more source

Bridging wheat kernel microstructure and flour rheology occurring during wheat germination. [PDF]

J Sci Food Agric
Gimhani I, Fu BX, Paliwal J, Rosell CM.
europepmc   +1 more source

Testing for Faecal Gluten Immunogenic Peptides: Is It Useful to Evaluate Adherence to Gluten-Free Diet? [PDF]

Acta Paediatr
Cenni S, Casertano M, D'Addio E, Pacella D, Tolone C, Martinelli M, Staiano A, Miele E, Strisciuglio C.   +8 more
europepmc   +1 more source