Results 21 to 30 of about 7,411 (220)

Comparison of neonatal and maternal outcomes of anti-diabetic drugs in the treatment of gestational diabetes mellitus: Findings from Bayesian network meta-analysis

Journal of Family Medicine and Primary Care, 2022
The safety and efficacy of different anti-diabetic drugs are not clear because of the lack of sufficiently powered clinical trials. This network meta-analysis was conducted to compare the efficacy and safety of three anti-diabetic drugs (insulin ...
Mandar K Shah, Mihika A Shah, Sharan D Shah, Parshwa K Shah, Kaushal Patel, Mamta Gupta   +5 more
doaj   +1 more source

Efficacy and safety of hypoglycemic agents on gestational diabetes mellitus in women: A Bayesian network analysis of randomized controlled trials

Frontiers in Public Health, 2022
ObjectiveTo compare the efficacy and safety of metformin, glyburide, and insulin for GDM, we conducted a subgroup analysis of outcomes for women with GDM according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG ...
Ting Wang, Ting Wang, Yingyu Jing, Haonan Guo, Jing Xu, Man Wang, Lili Huang, Huan Chen, Wei Cui, Lin Song, Xiang Liu, Bo Sun, Ning Wang, Ning Wang   +13 more
doaj   +1 more source

Long-Term Oral Treatment with Non-Hypoglycemic Dose of Glibenclamide Reduces Diabetic Retinopathy Damage in the Goto-KakizakiRat Model

Pharmaceutics, 2021
Diabetic retinopathy (DR) remains a major cause of vision loss, due to macular edema, retinal ischemia and death of retinal neurons. We previously demonstrated that acute administration of glibenclamide into the vitreous, or given orally at a non ...
Marianne Berdugo, Kimberley Delaunay, Cécile Lebon, Marie-Christine Naud, Lolita Radet, Léa Zennaro, Emilie Picard, Alejandra Daruich, Jacques Beltrand, Elsa Kermorvant-Duchemin, Michel Polak, Patricia Crisanti, Francine F. Behar-Cohen   +12 more
doaj   +1 more source

Inhibition of SUR1 Decreases the Vascular Permeability of Cerebral Metastases

Neoplasia: An International Journal for Oncology Research, 2013
Inhibition of sulfonylurea receptor 1 (SUR1) by glyburide has been shown to decrease edema after subarachnoid hemorrhage. We investigated if inhibiting SUR1 reduces cerebral edema due to metastases, the most common brain tumor, and explored the putative ...
Eric M Thompson, Gregory L Pishko, Leslie L Muldoon, Edward A Neuwelt   +3 more
doaj   +1 more source

Comparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis.

PLoS ONE, 2017
ObjectiveThe aim of this meta-analysis was to determine the efficacy and safety of glyburide as a treatment for gestational diabetes mellitus (GDM) compared to insulin.MethodsA meta-analysis was conducted to compare the management of gestational diabetes
Rongjing Song, Ling Chen, Yue Chen, Xia Si, Yi Liu, Yue Liu, David M Irwin, Wanyu Feng   +7 more
doaj   +1 more source

The Effect of KATP Channel Blocker Glibenclamide on CGRP-Induced Headache and Hemodynamic in Healthy Volunteers

Frontiers in Physiology, 2021
BackgroundCalcitonin gene-related peptide (CGRP) dilates cranial arteries and triggers headache. The CGRP signaling pathway is partly dependent on activation of ATP-sensitive potassium (KATP) channels. Here, we investigated the effect of the KATP channel
Hande Coskun, Fatima Azzahra Elbahi, Fatima Azzahra Elbahi, Mohammad Al-Mahdi Al-Karagholi, Hashmat Ghanizada, Majid Sheykhzade, Messoud Ashina, Messoud Ashina   +7 more
doaj   +1 more source

Possible Synergistic Antidiabetic Effects of Quantified Artemisia judaica Extract and Glyburide in Streptozotocin-Induced Diabetic Rats via Restoration of PPAR-α mRNA Expression

Biology, 2021
Several members of the genus Artemisia are used in both Western and African traditional medicine for the control of diabetes. A considerable number of diabetic patients switch to using oral antidiabetic drugs in combination with certain herbs instead of ...
Abdulaziz S. Saeedan, Gamal A. Soliman, Rehab F. Abdel-Rahman, Reham M. Abd-Elsalam, Hanan A. Ogaly, Khalid M. Alharthy, Maged S. Abdel-Kader   +6 more
doaj   +1 more source

Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis

Journal of Diabetes Research, 2019
To compare the efficacy and safety of metformin, glyburide, and insulin in treating gestational diabetes mellitus (GDM), a meta-analysis of randomized controlled trials (RCTs) was conducted. PubMed, Embase, CINAHL, Web of Science, and Cochrane Library to
Lanlan Guo, Jing Ma, Jia Tang, Dingyao Hu, Wei Zhang, Xue Zhao   +5 more
doaj   +1 more source

Effects of diabetic pharmacotherapy on prolactin hormone in patients with type 2 diabetes mellitus: Bane or Boon

Journal of Advanced Pharmaceutical Technology & Research, 2019
Prolactin is a polypeptide hormone secreted from the anterior part of the pituitary gland which was implicated as a diabetogenic factor in the pathogenesis of type 2 diabetes mellitus (T2DM).
Huda Abdulbaki Rasheed, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Nawar Raad Hussien, Marwa S Al-Nami   +4 more
doaj   +1 more source

Development and Characterization of Liquisolid Tablets Based on Mesoporous Clays or Silicas for Improving Glyburide Dissolution

Pharmaceutics, 2020
The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets based on a liquisolid approach.
Marzia Cirri, Paola Mura, Maurizio Valleri, Letizia Brunetti   +3 more
doaj   +1 more source