Results 31 to 40 of about 7,638 (174)

Clinical Trial Design—A Review—With Emphasis on Acute Intervertebral Disc Herniation

open access: yesFrontiers in Veterinary Science, 2020
There is a clear need for new methods of treatment of acute disc herniation in dogs, most obviously to address the permanent loss of function that can arise because of the associated spinal cord injury.
Nick D. Jeffery   +21 more
doaj   +1 more source

11 C-glyburide PET imaging unveils the negligible brain penetration of glyburide in humans

open access: yes, 2019
International audienceKimberly and coworkers reported the beneficial effects of intravenous glyburide on the clinical outcome of brain edema. We developed the carbon-11 radiolabeled analogue of glyburide to study the body distribution of this compound ...
Marie, Solène   +5 more
core   +1 more source

Glyburide inhibits the bone resorption induced by traumatic occlusion in rats. [PDF]

open access: yes, 2020
福岡歯科大学博士(歯学)2019年度To examine whether glyburide inhibits bone destruction caused by traumatic occlusion in a rat occlusal trauma model.Excessive mechanical stress, such as traumatic occlusion, induces expression of IL-1β and may be involved in bone ...
Arita, Yoichi   +19 more
core   +2 more sources

A review of current treatment strategies for gestational diabetes mellitus

open access: yesDrugs in Context, 2015
Approximately 90% of diabetes cases in pregnant women are considered gestational diabetes mellitus (GDM). It is well known that uncontrolled glucose results in poor pregnancy outcomes in both the mother and fetus. Worldwide there are many guidelines with
Kristi W Kelley   +2 more
doaj   +1 more source

Glycemic control and neonatal outcomes in women with gestational diabetes mellitus treated using glyburide, metformin, or insulin: a pairwise and network meta-analysis

open access: yesBMC Endocrine Disorders, 2021
Aims We aimed to assess the comparative efficiency and safety of the use of glyburide, metformin, and insulin in gestational diabetes mellitus (GDM). Methods We searched for randomized controlled trials that compared glyburide, metformin, and insulin in ...
Dan-Qing Yu   +8 more
doaj   +1 more source

Glyburide reduces macrophage IL1β secretion.

open access: yes, 2013
Note. Gb = glyburide; IL = interleukin. Primary bone marrow-derived macrophages were infected with B. pseudomallei for 30 min (multiplicity of infection 25 cfu/cell) and incubated with 0 µM (control), 100 µM or 1000 µM glyburide.
Tassili A. Weehuizen (473323)   +11 more
core   +1 more source

A comparative study of metformin and glyburide in gestational diabetes mellitus [PDF]

open access: yes, 2017
Background: Incidence of gestational diabetes mellitus (GDM) is increasing worldwide. GDM provides a window of opportunity for the primary prevention of the type 2 diabetes by preventing transgeneration transmission to fetus. Insulin in management of GDM
Dhara Prajapati   +9 more
core   +1 more source

Maternal outcomes comparing glyburide and insulin.

open access: yes, 2014
Maternal outcomes comparing glyburide and insulin.
Muhammad Amin (169590)   +2 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Differential effect of metformin and/or glyburide on apelin serum levels in patients with type 2 diabetes mellitus: Concepts and clinical practice

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2018
Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant adipocytokine changes which may play an important role in the progression of insulin resistance and micro- and macro-vascular complications. Therefore, the objective of this
Hayder M Al-Kuraishy   +3 more
doaj   +1 more source

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