Results 31 to 40 of about 7,411 (220)

Quantification of metformin and glyburide in blood for paediatric endocrinology

Acta Pediátrica de México, 2014
Background: The recent use of antidiabetic drugs such as metformin and glyburide for the treatment and control of childhood obesity, insulin resistance and type II diabetes mellitus in children and adolescents, has encouraged physicians to determine ...
Radamés Alemón-Medina, Juan Luis Chávez-Pacheco, Blanca Ramírez-Mendiola, Liliana Rivera-Espinosa, Raquel García-Álvarez   +4 more
doaj   +1 more source

The clinical aspects ot the sulphonylurea compounds from the position of the cardioprotective approach at patient with type 2 diabetes, using glucocardiomonitoring

Сахарный диабет, 2022
BACKGRAUND: Now the trend of Type 2 Diabetes Mellitus (T2DM) management from glucocentric to cardioprotective approach take place, and it especially relevant for the multiple group of patients with T2DM using Sulphonylurea (SU).
N. A. Chernikova, L. L. Kamynina, A. S. Аmetov, D. A. Sychov   +3 more
doaj   +1 more source

Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis.

PLoS Medicine, 2020
BackgroundFetal growth in gestational diabetes mellitus (GDM) is directly linked to maternal glycaemic control; however, this relationship may be altered by oral anti-hyperglycaemic agents.
Jane L Tarry-Adkins, Catherine E Aiken, Susan E Ozanne   +2 more
doaj   +1 more source

Gestational diabetes mellitus: Non-insulin management

Indian Journal of Endocrinology and Metabolism, 2011
Gestational diabetes mellitus (GDM) complicates a substantial number of pregnancies. There is consensus that in patients of GDM, excellent blood glucose control, with diet and, when necessary, oral hypoglycemics and insulin results in improved perinatal ...
Navneet Magon, V Seshiah
doaj   +1 more source

Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats

Molecular Pain, 2011
Background Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals. Ion channels play a vital role in pain signal initiation and conduction.
Zhang Hailin, Wang Chao, Du Xiaona
doaj   +1 more source

Clinical Trial Design—A Review—With Emphasis on Acute Intervertebral Disc Herniation

Frontiers in Veterinary Science, 2020
There is a clear need for new methods of treatment of acute disc herniation in dogs, most obviously to address the permanent loss of function that can arise because of the associated spinal cord injury.
Nick D. Jeffery, Natasha J. Olby, Sarah A. Moore, The Canine Spinal Cord Injury Consortium (CANSORT-SCI), Sarah A. Moore, Natasha J. Olby, Kady M. Gjessing, Rhanna M. Davidson, Jonathan M. Levine, Helen McWhorter, Melissa J. Lewis, Nick D. Jeffery, Maureen E. Mullins, Ronaldo Casimiro da Costa, Yvette S. Nout-Lomas, Joe Fenn, Nicolas Granger, Ingo Spitzbarth, Veronika M. Stein, Andrea Tipold, Ji-Hey Lim, Holger Volk   +21 more
doaj   +1 more source

A review of current treatment strategies for gestational diabetes mellitus

Drugs in Context, 2015
Approximately 90% of diabetes cases in pregnant women are considered gestational diabetes mellitus (GDM). It is well known that uncontrolled glucose results in poor pregnancy outcomes in both the mother and fetus. Worldwide there are many guidelines with
Kristi W Kelley, Dana G Carroll, Allison Meyer   +2 more
doaj   +1 more source

Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus

Clinical Pharmacology & Therapeutics, 2020
In gestational diabetes mellitus (GDM), women are unable to compensate for the increased insulin resistance during pregnancy. Data are limited regarding the pharmacodynamic effects of metformin and glyburide during pregnancy. This study characterized insulin sensitivity (SI), β‐cell responsivity, and disposition index (DI) in women with GDM utilizing a
Diana L. Shuster, Laura M. Shireman, Xiaosu Ma, Danny D. Shen, Shannon K. Flood Nichols, Mahmoud S. Ahmed, Shannon Clark, Steve Caritis, Raman Venkataramanan, David M. Haas, Sara K. Quinney, Laura S. Haneline, Alan T. Tita, Tracy A. Manuck, Kenneth E. Thummel, Linda Morris Brown, Zhaoxia Ren, Zane Brown, Thomas R. Easterling, Mary F. Hebert   +19 more
openaire   +3 more sources

Stretching Scarce Authorizing Legislation as Far as Possible: A Legislative History of the 340B Drug Pricing Program

The Milbank Quarterly, EarlyView.
Policy Points The original purpose of the 340B program was to exempt Public Health Service Act funded clinics and state and local public hospitals from the inflationary best‐price component of the recently enacted Medicaid drug rebate program. The secondary purpose was to reduce drug prices for these clinics and hospitals in order to preserve and ...
SAYEH NIKPAY, MIKAYLA REINKE, NICOLE QUINONES   +2 more
wiley   +1 more source

Differential effect of metformin and/or glyburide on apelin serum levels in patients with type 2 diabetes mellitus: Concepts and clinical practice

Journal of Advanced Pharmaceutical Technology & Research, 2018
Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant adipocytokine changes which may play an important role in the progression of insulin resistance and micro- and macro-vascular complications. Therefore, the objective of this
Hayder M Al-Kuraishy, Ali I Al-Gareeb, Huda J Waheed, Thabat J Al-Maiahy   +3 more
doaj   +1 more source