Results 111 to 120 of about 19,474 (199)

Plasma ADMA associates with all-cause mortality in renal transplant recipients [PDF]

, 2015
Asymmetric dimethylarginine (ADMA) is a key endogenous inhibitor of endothelial NO synthase that affects endothelial function, blood pressure and vascular remodeling.
Bakker, Stephan J L, Beckmann, Bibiana, de Borst, Martin H, Feelisch, Martin, Frenay, Anne-Roos S., Navis, Gerjan, Tsikas, Dimitrios, van den Berg, Else, van Goor, Harry   +8 more
core   +2 more sources

Determination of supplier-to-supplier and lot-to-lot variability in glycation of recombinant human serum albumin expressed in Oryza sativa.

PLoS ONE, 2014
The use of different expression systems to produce the same recombinant human protein can result in expression-dependent chemical modifications (CMs) leading to variability of structure, stability and immunogenicity.
Grant E Frahm, Daryl G S Smith, Anita Kane, Barry Lorbetskie, Terry D Cyr, Michel Girard, Michael J W Johnston   +6 more
doaj   +1 more source

Targeted, structured text messaging to improve dietary and lifestyle behaviours for people on maintenance haemodialysis (KIDNEYTEXT): Study protocol for a randomised controlled trial [PDF]

, 2019
Introduction Managing nutrition is critical for reducing morbidity and mortality in patients on haemodialysis but adherence to the complex dietary restrictions remains problematic.
Brown, Mark, Campbell, Katrina L., Chow, Clara, Craig, Jonathan, Howard, Kirsten, Howell, Martin, Khalid, Rabia, Lee, Vincent W., Stevenson, Jessica, Sud, Kamal, Teixeira-Pinto, Armando, Thiagalingam, Aravinda, Tong, Allison   +12 more
core   +1 more source

Anthracene boronic acid methacrylate-based fluorescence activation assay for determination of glycated proteins in biological samples

Talanta Open
There is a current unmet medical need for the creation and development of point-of-care diagnostic tests/devices that can determine if a given individual is diabetic, pre-diabetic or normal.
Jaroslava Bezdekova, Kristyna Pavelicova, Dattatry Shivajirao Bhosale, Silvie Kozakova, Lenka Pavlikova, Jihao Yu, Jan Bartacek, Jan Svoboda, Milos Sedlak, Andrew D. Miller, Marketa Vaculovicova   +10 more
doaj   +1 more source

Evaluation of oxidative stress in Insulin Dependent Diabetes Mellitus (IDDM) patients [PDF]

, 2007
Background Free radical mediated oxidative stress is mainly involved in the pathogenesis of diabetic complications. Proteins and lipids are among the prime targets for oxidative stress.
Vadde Ramakrishna, Rama Jailkhani
core   +2 more sources

Advances in electrochemical biosensors employing carbon-based electrodes for detection of biomarkers in diabetes mellitus

ADMET and DMPK
Background and purpose: The increase in diabetes cases has become a major concern in the healthcare sector, necessitating the development of efficient and minimal diagnostic methods.
Serly Zuliska, Iman Permana Maksum, Yasuaki Einaga, Grandprix Thomreys Marth Kadja, Irkham Irkham   +4 more
doaj   +1 more source

Pharmacological Activities of Zingiber officinale Roscoe: Inhibition of HSA Protein Glycation, Structure Stability and Function Restoration

Pharmaceuticals
Background: Controlled non-enzymatic glycation reactions are common under normal physiological conditions. However, during elevated blood glucose conditions, the glycation reactions are accelerated, leading to the formation of toxic compounds such as ...
Mohd Wajid Ali Khan, Subuhi Sherwani, Muna H. E. Alshammari, Abdulmohsen K. D. Alsukaibi, Wahid Ali Khan, Ashanul Haque, Khalaf M. Alenezi, Uzma Shahab   +7 more
doaj   +1 more source

The protective effects of pomelo extract (Citrus grandis L. Osbeck) against fructose-mediated protein oxidation and glycation [PDF]

, 2013
Chronic hyperglycemia induces non-enzymatic protein glycation, which plays an important role in the development of diabetic complications. Immense efforts have been made to determine effective antiglycation compounds from natural products.
Adisakwattana, Sirichai, Caengprasath, Natarin, Mäkynen, Kittana, Ngamukote, Sathaporn   +3 more
core  

Canine diabetes mellitus demonstrates multiple markers of chronic inflammation including Th40 cell increases and elevated systemic-immune inflammation index, consistent with autoimmune dysregulation

Frontiers in Immunology
IntroductionCanine diabetes mellitus (CDM) is a relatively common endocrine disease in dogs. Many CDM clinical features resemble human type 1 diabetes mellitus (T1DM), but lack of autoimmune biomarkers makes calling the disease autoimmune controversial ...
Gisela Vaitaitis, Tracy Webb, Craig Webb, Christina Sharkey, Steve Sharkey, Dan Waid, David H. Wagner, David H. Wagner   +7 more
doaj   +1 more source

The Effect of the Hydroalcoholic Extract of Persian shallot(Allium Hirtifolium boiss) on Albumin Glycation [PDF]

, 2016
زمینه و هدف: هیپرگلیسمی دیابتی باعث قندی شدن پروتئین‌های بدن و به نوبه خود موجب تغییر در ساختمان و عملکرد آن ها می‌گردد. برخی از عوارض بیماری دیابت از جمله نفروپاتی و رتینوپاتی به دلیل واکنش قندی شدن غیر آنزیمی پروتئین‌ها است.
Asadpour, Mohammad., Fattahpour, Shirin., Hajizade, Mohammadreza., Hassanshahi, Gholamhossein., Hosseini Baharanchi, Farzaneh sadat., Khoshdel, Alireza., Mahmoodi, Mehdi., Mirzai, MohammadReza.   +7 more
core