Results 121 to 130 of about 4,588 (217)

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo   +4 more
wiley   +1 more source

Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins   +9 more
wiley   +1 more source

Diabetic Corneal Neuropathy as a Window Into Diabetic Foot Risk: A Large‐Scale Association Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the association between diabetic corneal neuropathy and diabetic foot risk by examining corneal nerve features, clinical characteristics, and tear mediators in patients with different diabetic foot risk categories. Methods In this cross‐sectional study, 710 participants underwent diabetic foot examination, in vivo confocal ...
Chang Liu   +12 more
wiley   +1 more source

Ultrafast python‐integrated single‐entity electrochemical sensor for detecting glycated albumin

open access: yesThe FEBS Journal, EarlyView.
Traditional biosensors suffer from the fact that recognition receptors are immobilised and that they denature on electrodes. Instead here we use receptors freely in solution, minimising surface compression and preserving activity to boost signal efficiency. Python‐driven processing turns the electrochemical response into a rapid, robust readout.
Zihni Onur Uygun
wiley   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

A novel all‐in‐one dynamic wrinkle evaluation system: Development, validation and application in cosmetic industries

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Photo grading of dynamic lines in the dynamic line repeatability validation study. Abstract Objective This study aimed to develop and validate a novel, integrated dynamic wrinkle assessment system based on standardized, real‐time and multi‐angle facial images and video recordings, and to explore its potential application in evaluating the anti‐wrinkle ...
Xingzuo Liu   +6 more
wiley   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh   +5 more
wiley   +1 more source

Periodontal Status of Type 1 Diabetes Mellitus and Healthy Pregnant Women: A Case–Control Pilot Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Aims This cross‐sectional ‘case–control’ pilot study aimed to compare the size of periodontal wounds, periodontal status and total inflammatory burden between pregnant women with type 1 diabetes mellitus (T1DM) and non‐diabetic pregnant women. Methods Fifteen T1DM pregnant women and 15 healthy pregnant women were included. Clinical parameters (
M. Janc   +4 more
wiley   +1 more source

Neutrophil Secretory Proteins Inhibit Calcium Oxalate Crystallisation and Crystal Growth, but Promote Crystal Aggregation

open access: yesImmunology, EarlyView.
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai   +2 more
wiley   +1 more source

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma   +3 more
wiley   +1 more source

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