Results 131 to 140 of about 87,156 (304)

Wnt Glycation Inhibits Canonical Signaling

, 2019
Glycation occurs as a non-enzymatic reaction between amino and thiol groups of proteins, lipids, and nucleotides with reducing sugars or α-dicarbonyl metabolites. The chemical reaction underlying is the Maillard reaction leading to the formation of
Rüdiger Horstkorte, Otmar Huber, Zhennan Ye, Martin Schmidt, Sonnhild Mittag, Andreas Simm   +5 more
core   +1 more source

The Endogenous Inhibitor of CETP, apoC1, Remains Ineffective In Vivo after Correction of Hyperglycemia in People with Type 1 Diabetes

Metabolites
ApolipoproteinC1 (apoC1) is the main physiological inhibitor of the cholesterol ester transfer protein (CETP). Increased CETP activity is associated with macrovascular complications in patients with type 1 diabetes (T1D).
Alexia Rouland, Thomas Gautier, Damien Denimal, Laurence Duvillard, Isabelle Simoneau, David Rageot, Bruno Vergès, Benjamin Bouillet   +7 more
doaj   +1 more source

Glycated Haemoglobin [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1993
openaire   +2 more sources

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review

Phytotherapy Research, EarlyView.
Research landscape and mechanistic insights into natural medicines for Alzheimer's disease. ABSTRACT Natural medicines have been widely investigated for Alzheimer's disease (AD), but the development of this field and the relationship between bibliometric themes and experimental evidence remain insufficiently characterized.
Maoning Wang, Xiaolian Zhang, Huaxian Yang, Jianhe Zhao, Wentao Wei, Qian Zhao, Wenjia Wang, Yunhui Hu, Jiansong Fang   +8 more
wiley   +1 more source

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

, 2017
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases known as synucleinopathies. The toxic properties of α-synuclein are conserved from yeast to man, but the precise underpinnings of ...
Oliveira, Luís M. A., Luisa V. Lopes (4181968), Francesca Munar (7744001), Oliveira, M., Gomes, Marcos A, Hugo Vicente Miranda, Irina Zamolo, Vicente Miranda, Hugo, Santos, N., Thomas M. Jovin, Zamolo, I., Luı´s M. A. Oliveira (7743983), Tania Simoes (7744004), Zweckstetter, Markus, Hilal A. Lashuel (261037), de Oliveira, Rita M, Markus Zweckstetter, Martins, Ivo C, Nuno C. Santos (354057), Martins, I., Engelender, S., Ana Ponces-Freire, Ponces-Freire, Ana, Francisco J. Enguita (261452), Ruth Rott (7743995), Simone Engelender (7744016), Breda, C., Hugo Vicente Miranda (3812248), Oliveira, L., Simões, Tânia, Rita M. de Oliveira, Olaf Riess (110686), Hilal A. Lashuel, Enguita, F., Carlos Cordeiro (279493), Alexandre Quintas (232621), Gomes, M., Francesca Munari, Wei Xiang, Marcos A. Gomes (7743992), Klucken, J., Luís M. A. Oliveira, Szego, Éva M., Klucken, Jochen, Simoes, T., Santos, Nuno C, Ivo C. Martins (1651531), Xiang, W., Miranda, H., Jochen Klucken (335764), Carlo Breda (5076125), Carlos Cordeiro, Simone Engelender, Riess, Olaf, de Oliveira, Rita M., Ekrem Darendelioglu, Oliveira, Luís M.A., Michael Heinrich, Enguita, Francisco Javier, Outeiro, Tiago F., Carlo Breda, Francisco J. Enguita, Breda, Carlo, Outeiro, Tiago F, de Oliveira, Rita Machado, Ferreira, Diana G, Szego, E., Ekrem Darendelioglu (7743986), Xiang, Wei, Zweckstetter, M., Luisa V. Lopes, Lashuel, Hilal A, Lopes, Luisa V., Outeiro, T., Lashuel, Hilal Ahmed, Flaviano Giorgini, Rita M. de Oliveira (7743989), Oliveira, Márcia, Ma´rcia Oliveira (7743998), Enguita, Francisco J, Munari, Francesca, Eva F. Rodrigues, Deborah Penque (2365399), Diana G. Ferreira, Eva F. Rodrigues (7744007), Ruth Rott, Zamolo, Irina, Jovin, Thomas M, Diana G. Ferreira (4006694), Rodrigues, E., Penque, D., Quintas, A., Lopes, L., Alexandre Quintas, Irina Zamolo (7744010), Nuno C. Santos, Giorgini, Flaviano, Outeiro, Tiago Fleming, Ferreira, D., Flaviano Giorgini (58325), Szego, Éva M, Thomas M. Jovin (9674), Ivo C. Martins, Martins, Ivo C., Ana Ponces-Freire (7744013), Wei Xiang (46368), Miranda, Hugo Vicente, Oliveira, Luís M A, Darendelioglu, Ekrem, Marcos A. Gomes, Rodrigues, Eva F., Ponces-Freire, A., Tânia Simões, Jovin, T., Quintas, Alexandre, E´ va M. Szego (7743980), Riess, O., Oliveira, Rita M. de, Penque, Deborah, Lashuel, H., Enguita, Francisco J., Freire, Ana Ponces, Rodrigues, Eva F, Lopes, Luisa V, de Oliveira, R., Cordeiro, C., Markus Zweckstetter (133481), Cordeiro, Carlos, Deborah Penque, Munari, F., Engelender, Simone, Éva M. Szegő, Jochen Klucken, Jovin, Thomas M., Lopes, Luisa Vaqueiro, Gomes, Marcos Antonio, Darendelioglu, E., Ferreira, Diana G., Heinrich, Michael, Santos, Nuno C., Márcia Oliveira, Giorgini, F., Tiago F. Outeiro (191379), Rott, Ruth, Tiago F. Outeiro, Lashuel, Hilal A., Gomes, Marcos A., Michael Heinrich (1375335), Rott, R., Olaf Riess, Vincente Miranda, H., Heinrich, M., Oliveira, R.   +152 more
core   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Biomarkers of Pre‐COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade

Respirology, EarlyView.
Identifying impaired lifetime lung function trajectories is key to identifying the preclinical phase of COPD (Pre‐COPD) or prognosis of COPD. We have identified that some circulating established COPD biomarkers differ across ‘pre‐COPD’ lung function trajectories, suggesting that some COPD‐specific pathobiological processes, including inflammation, are ...
Dinh S. Bui, Don Vicendese, Jonathan Pham, Nur Sabrina Idrose, Adrian Lowe, Caroline Lodge, Raisa Cassim, Chamara Senaratna, Gayan Bowatte, Garun Hamilton, Alan James, Paul Thomas, Richard Wood‐Baker, Peter Frith, Gary Anderson, Philip M. Hansbro, Graeme Zosky, George Washko, Michael J. Abramson, Rosa Faner, Alvar Agusti, Jennifer Perret, E. Haydn Walters, Shyamali C. Dharmage   +23 more
wiley   +1 more source

Lipoprotein glycation in atherogenesis

, 2009
There has been increasing interest in investigating the role of glycation as an atherogenic modification of lipoproteins; especially after the failure of antioxidant therapy to suppress the incidence of atherogenic cardiovascular diseases in high-risk ...
Sharma, Reena, Reena Sharma, Soran, Handrean, Durrington, Paul N., Nahla Younis, Handrean Soran, Charlton-Menys, Valentine, Younis, Nahla, Younis, Nahla N., Valentine Charlton–Menys, Paul Durrington   +10 more
core   +1 more source

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

Small, EarlyView.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi, Minjeong Kim, Sang Jin Lee, Su‐Hwan Kim   +3 more
wiley   +1 more source