Results 141 to 150 of about 4,588 (217)

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Assessment of faecal calprotectin in neonatal calf diarrhoea using a human ELISA kit: Associations with faecal score and serum biochemical markers

Veterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diarrhoea in newborn calves, which occurs in the first month of life and is caused by various pathogens, poses a significant threat to livestock industries. Therefore, timely diagnosis of enteritis in calves can be advantageous. Objective This study aimed to determine the efficacy of faecal calprotectin as a biomarker indicating ...
Narges Lotfalizadeh, Farima Jahromi, Alborz Yadollahi, Saeed Nazifi   +3 more
wiley   +1 more source

Relation Between Calcaneal Fat Pad Thickness and Plantar Foot Ulceration in Patients With Type 2 Diabetes Mellitus

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Introduction Thinning of fat pads may elevate the risk of developing plantar foot ulcers potentially resulting in lower‐extremity amputations. Evaluating whether fat pad thickness is associated with plantar foot ulceration could aid in early risk detection. This study therefore aims to compare fat pad thickness between type 2 diabetes mellitus
Sem J. van den Nieuwenhof, Margot H. M. Heijmans, Jeroen J. van der Reijden, Chantal D. Bakker, Roel H. D. Vaes   +4 more
wiley   +1 more source

Carbonyl stress markers are associated with binge‐eating/purging behavior of anorexia nervosa: A pilot study

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
This study investigated Advanced Glycation End Products (AGEs), reflecting carbonyl stress from glycation and oxidation reactions, as potential biomarkers for identifying binge‐eating/purging behaviors in anorexia nervosa (AN). Finding revealed higher fingertip AGE levels in the binge‐eating/purging subtype (ANBP) compared to the restricting subtype ...
Kana Morimoto, Masanori Isobe, Tomomi Noda, Keima Tose, Momo Sunada, Koichi Tabata, Momoka Taniguchi, Makoto Arai, Toshiya Murai   +8 more
wiley   +1 more source

Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone

eFood, Volume 7, Issue 4, August 2026.
Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu, Ziyong Mao, Jesus Simal‐Gandara, Zi Chen, Hui Cao   +4 more
wiley   +1 more source

Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review

eFood, Volume 7, Issue 4, August 2026.
Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu, Manxi Wu, Hui Xu, Jiebiao Chen, Wen Cai, Han Yang, Hujing Cao, Xinlin Huang, Jinping Cao, Chongde Sun, Yue Wang, Dongliang Li   +11 more
wiley   +1 more source