Results 161 to 170 of about 89,718 (303)

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

Protein glycation reactions

, 2000
The reactions of the early and intermediate stages of protein glycation were studied using bovine serum albumin and hen egg white lysozyme as model proteins, and D-glucose and D-fructose as model reducing sugars.
Yeboah, Faustinus Kwabena.
core  

Absolute and Relative Quantification of Glycation on Biotherapeutic IgGs Using Heavy Isotope-Labeled Proteins. [PDF]

J Biomol Tech
Priya S, Popov M, Orlando R.
europepmc   +1 more source

Male Sexual and Reproductive Health in Diabetes and Obesity Pharmacotherapy: A Source‐Triangulated Counseling Map

Andrology, EarlyView.
ABSTRACT Background Drugs used for diabetes and obesity increasingly shape male sexual and reproductive counseling, but clinical studies, trial registrations, regulatory labels, and patents answer different questions. Objectives The objective is to map these sources and define what each can support when counseling men receiving metabolic drugs ...
Marek Broul, Michal Dubský, Aneta Hujová, Michaela Liegertová   +3 more
wiley   +1 more source

Protein glycosylation and glycation in Alzheimer's disease: mechanisms, crosstalk, and therapeutic perspectives. [PDF]

Front Neurosci
Luo Y, Gu J.
europepmc   +1 more source

Diet and risk of bladder cancer: a systematic review of epidemiological evidence

BJU International, EarlyView.
Purpose Although tobacco use and occupational exposures are established risk factors for urothelial cancer (UC), the influence of dietary factors remains uncertain. We conducted a systematic review to synthesize evidence from prospective cohort studies examining associations between dietary exposures and UC incidence. Methods A comprehensive literature
Keiichiro Miyajima, Marcin Miszczyk, Navid Roessler, Shota Inoue, Paweł Rajwa, Akihiro Matsukawa, Fumihiko Urabe, Keiichiro Mori, Takafumi Yanagisawa, Pierre I. Karakiewicz, Jeremy Yuen‐Chun Teoh, Alberto Briganti, Lin Yang, Eva Schernhammer, Takahiro Kimura, Shahrokh F. Shariat   +15 more
wiley   +1 more source

Comparative review of glycated albumin detection from conventional colorimetric assays to Raman spectroscopy, surface-enhanced Raman scattering, and surface plasmon resonance. [PDF]

RSC Adv
Jayasekara LASP, Senadeera SPNN, Samarathunga LM, Priyashantha PRTD, Kottahachchi DU, Ranaweera CB.   +5 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Dietary and Circulating Advanced Glycation End Products in Relation to Inflammation and Cognitive Function in Healthy Young Adults. [PDF]

Nutrients
Aydin Cil M, Karatas N, Ozgeris FB, Tasgin E, Sari S, Özkalaycı RE.   +5 more
europepmc   +1 more source

Positive modulation of glucagon‐like peptide 1 (GLP‐1) receptor by endogenous haemorphins with implications in glucose metabolism and diabetes

British Journal of Pharmacology, EarlyView.
Haemorphins act on GLP‐1 receptor (GLP‐1R) activity and signalling in a positive allosteric manner. This leads to potentiated GLP‐1‐mediated activity and signalling, as well as insulin synthesis, which may have implications for glucose metabolism and, thereby, diabetes and obesity. (The graph was created in BioRender.com).
Farheen Badrealam Khan, Rwdah Mohamed Alameri, Yasir S. Raouf, Damien Maurel, Naiem Ahmad Wani, Anatoliy Shmygol, Irfa Anwar, Heng B. See, Elizabeth K. M. Johnstone, Elodie Dupuis, Eric Trinquet, Kevin D. G. Pfleger, Emilia Oueis, Mohammed Akli Ayoub   +13 more
wiley   +1 more source