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Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract BACKGROUND Major neurocognitive disorder (MNCD) represents a critical public health crisis. From the two waves of the Longitudinal Aging Study in India‐Diagnostic Assessment of Dementia, we investigated the predictive power of longitudinal alterations in plasma proteins to predict the progression from mild cognitive impairment (MCI) to MNCD in
Rashmita Pradhan +7 more
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Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research
BioFactors, Volume 52, Issue 4, July/August 2026.This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen +2 more
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Chronicle of Diabetes Research and Practice, 2022
Diabetes is considered as a risk factor for the severity of coronavirus disease 2019 (COVID-19). The mortality rate of COVID-19 was found to be high among patients with diabetes. The exact molecular mechanism involved in diabetes-associated COVID-19 severity is not established.
Sneha B. Bansode +3 more
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Diabetes is considered as a risk factor for the severity of coronavirus disease 2019 (COVID-19). The mortality rate of COVID-19 was found to be high among patients with diabetes. The exact molecular mechanism involved in diabetes-associated COVID-19 severity is not established.
Sneha B. Bansode +3 more
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Role of glycated proteins in vivo: Enzymatic glycated proteins and non-enzymatic glycated proteins
Food Research International, 2022Glycated protein is a kind of substance that often exists in the human body through the combination of sugar and protein under enzyme or non-enzyme conditions. Enzyme-catalyzed glycated proteins are widely distributed in the human body and participate in life activities such as human growth and immune regulation. Non-enzymatic glycated protein is often
Qian, Wu +9 more
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BioEssays, 1994
AbstractAtherosclerosis is the major cause of death in the industrialised world. Though much work on the pathogenesis of atherosclerosis points to ‘oxidised’ low density lipoprotein (;LDL) as a key aeitological feature in the generation of the atherosclerotic plaque, the nature of this ‘oxidised’ LDL in vivo remains an enigma.
C A, Colaco, B J, Roser
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AbstractAtherosclerosis is the major cause of death in the industrialised world. Though much work on the pathogenesis of atherosclerosis points to ‘oxidised’ low density lipoprotein (;LDL) as a key aeitological feature in the generation of the atherosclerotic plaque, the nature of this ‘oxidised’ LDL in vivo remains an enigma.
C A, Colaco, B J, Roser
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Clinica Chimica Acta, 2020
Glycated hemoglobin (HbA1c) is the reference test for long-term glucose monitoring. However, HbA1c is not recommended in several situations such as hemoglobinopathies, pregnancy or chronic kidney disease. The quantification of serum glycated albumin (GA) can serve as an alternative in these situations.
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Glycated hemoglobin (HbA1c) is the reference test for long-term glucose monitoring. However, HbA1c is not recommended in several situations such as hemoglobinopathies, pregnancy or chronic kidney disease. The quantification of serum glycated albumin (GA) can serve as an alternative in these situations.
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Journal of Chromatography B: Biomedical Sciences and Applications, 1988
The association between elevated levels of glycated haemoglobins and diabetes mellitus has been known for twenty years [92]. Since then the determination of glycated haemoglobins has become a valuable tool for the objective assessment of long-term glycaemia in diabetic patients.
Flückiger R, Mortensen HB
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The association between elevated levels of glycated haemoglobins and diabetes mellitus has been known for twenty years [92]. Since then the determination of glycated haemoglobins has become a valuable tool for the objective assessment of long-term glycaemia in diabetic patients.
Flückiger R, Mortensen HB
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Lipid glycation and protein glycation in diabetes and atherosclerosis
Amino Acids, 2010Recent instrumental analyses using a hybrid quadrupole/linear ion trap spectrometer in LC-MS/MS have demonstrated that the Maillard reaction progresses not only on proteins but also on amino residues of membrane lipids such as phosphatidylethanolamine (PE), thus forming Amadori-PE (deoxy-D: -fructosyl PE) as the principal products.
Teruo, Miyazawa +3 more
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Measurement of Protein Glycation, Glycated Peptides, and Glycation Free Adducts
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2005Protein glycation adducts, early glycation adducts, such as N ∊ -fructosyl-lysine, and advanced glycation end products (AGEs) are uremic toxins. Glycation adducts are found in plasma and tissue proteins (glycation adduct residues), in peptides (glycation adduct peptide residues), and glycated
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