Results 161 to 170 of about 87,156 (304)

N-Acetyl Cysteine Mitigates d-Ribose-Induced Protein Glycation and Aggregation Through Multiple Protective Mechanisms. [PDF]

IUBMB Life
Nabi R, Faruqui T, Khan MS, Alafaleq NO, Alvi SS, Puri P, Waiz M, Yusuf M, Ahmad N, Khan MS, Ahmad S.   +10 more
europepmc   +1 more source

Dysglycaemia and Autonomic Dysfunction: The Diabetes Prevention Program Outcomes Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Limited data on the link between various measures of glycemia and metabolism and autonomic dysfunction exist. We assessed the association of fasting plasma glucose [FPG], glycated haemoglobin [HbA1C], fasting insulin, and HOMA‐IR and cardiac autonomic function measures separately for men and women in the Diabetes Prevention Program ...
Justin B. Echouffo‐Tcheugui, Xun Liu, Elsayed Z. Soliman, Xavier Pi‐Sunyer, Sherita H. Golden, Sam Dagogo‐Jack, Neil H. White, Matthew Budoff, Uzoma Ibebuogu, Christine Darwin, William C. Knowler, Marinella Temprosa, on behalf of the DPP Research Group   +12 more
wiley   +1 more source

Mass Spectrometry-Based Comparative Evaluation of Forced Glycation Profiles of Therapeutic Monoclonal Antibodies. [PDF]

Biomedicines
Pamukcu C, Atik AE.
europepmc   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Effect of glucose-induced glycation on the interaction behavior of furan derivatives with chicken skin collagen. [PDF]

Food Chem X
Zhou G, Cheng K, Liu H, Li K, Liu E, Liu D.   +5 more
europepmc   +1 more source

Oleanolic Acid‐Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González, Alejandro Matamoros‐Domínguez, Juan Manuel Espinosa‐Cabello, Gisela Pérez‐Muñoz, Manuel Jesús León Aranda, María Del Carmen Roque‐Cuellar, Silvia García‐Rey, Andrés Jiménez‐Sánchez, Antonio Jesús Martínez‐Ortega, Miguel Ángel Mangas‐Cruz, Isabel Cerrillo, Javier S. Perona, Pedro Pablo García‐Luna, Elena María Yubero‐Serrano, José María Castellano   +14 more
wiley   +1 more source

Antiglycation of Insulin by Selected Six Bioactive Peanut Sprout Stilbenoids and Demonstration of Methylglyoxal-Mediated Biphasic Insulin Glycation by <i>O</i>-Phenylenediamine Derivatization. [PDF]

Food Sci Nutr
Chiu PC, Lin SM, Li YJ, Lo CY, Chiou RY.
europepmc   +1 more source

Ultrafast python‐integrated single‐entity electrochemical sensor for detecting glycated albumin

The FEBS Journal, EarlyView.
Traditional biosensors suffer from the fact that recognition receptors are immobilised and that they denature on electrodes. Instead here we use receptors freely in solution, minimising surface compression and preserving activity to boost signal efficiency. Python‐driven processing turns the electrochemical response into a rapid, robust readout.
Zihni Onur Uygun
wiley   +1 more source

Glycation at the Gate: A Brain Endothelial Glycocalyx Model and Therapeutic Roadmap for Alzheimer's Disease. [PDF]

Biomedicines
Tarawneh R.
europepmc   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source