Results 191 to 200 of about 130,285 (343)

Fingertip skin autofluorescence as a non‐invasive marker for vascular complications in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This multicenter study demonstrated that fingertip autofluorescence, measured non‐invasively, correlates with clinical risk factors and vascular complications in patients with type 2 diabetes. Our findings suggest that fingertip autofluorescence may serve as a convenient marker for evaluating both microvascular and macrovascular complications in ...
Minoru Takeshita, Takeshi Matsumura, Aiko Arimura, Hiroyuki Takahashi, Yoshimi Muta, Shigeru Kawade, Dai Yamagami, Takahisa Deguchi, Tatsuya Kondo, Mikihiro Yamanaka, Ryoji Nagai, Daiji Kawanami, Toshihiko Yanase, Takashi Nomiyama, Yoshihiko Nishio, Eiichi Araki, Naoto Kubota   +16 more
wiley   +1 more source

Advanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal Kupffer and endothelial cells [PDF]

, 1997
Bård Smedsrød, Jukka Melkko, Norie Araki, Hiroyuki Sano, Seikoh Horiuchi   +4 more
openalex   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

The receptor for advanced glycation end-products has a central role in mediating the effects of advanced glycation end-products on the development of vascular disease in diabetes mellitus [PDF]

, 1996
Osamu Hori, S D Yan, Satoshi Ogawa, Kosuke Kuwabara, Makoto Matsumoto, Donnel B. Stern, A M Schmidt   +6 more
openalex   +1 more source

Collagen organisation in the fibrous joint capsules in the digits of the human hand

Journal of Anatomy, EarlyView.
The function of the finger joints is important for daily life. In this review of the literature, we consider the role of collagen and its organization within the fibrous finger joint capsules of the interphalangeal (IP) joints and investigate the relationships between collagen orientation and joint function. Abstract Normal function of the hand and, in
Fiona R. Saunders, Ronald G. Coutts, Richard M. Aspden, Flora Gröning   +3 more
wiley   +1 more source

Multidimensional associations of physical performance, balance, wellness and daily activities with frailty in older adults with coexisting frailty and diabetes

Journal of Clinical Nursing, EarlyView.
Abstract Background The coexistence of frailty and type 2 diabetes mellitus in the older population heightens the risk of adverse events. However, research on functional and wellness factors associated with frailty in this population is limited. Purpose To investigate the associations of physical performance, functional dependency, physical activity ...
Juan Corral‐Pérez, Alba Mier, María Ángeles Vázquez‐Sánchez, María Naranjo‐Márquez, Jesus Gustavo Ponce‐Gonzalez, Cristina Casals   +5 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

The Gfr Uptake System Provides a Context‐Dependent Fitness Advantage to Salmonella Typhimurium SL1344 During the Initial Gut Colonization Phase

Molecular Microbiology, EarlyView.
Diet–microbiota interactions shape colonization resistance. While the microbiota restricts pathogens like Salmonella through nutrient competition, Salmonella can exploit private nutrients such as fructoselysine (FL), abundant in processed foods but inaccessible to most microbes.
Lea Fuchs, Cora Lisbeth Dieterich, Elena Melgarejo Ros, Philipp Keller, Anna Sintsova, Leanid Laganenka, Thomas A. Scott, Christopher Schubert, Shinichi Sunagawa, Julia A. Vorholt, Jörn Piel, Wolf‐Dietrich Hardt, Bidong D. Nguyen   +12 more
wiley   +1 more source

Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses. [PDF]

NPJ Parkinsons Dis
Vasili E, König A, Al-Azzani M, Bosbach C, Gatzemeier LM, Thom S, Chegão A, Miranda HV, Steinem C, Erskine D, Outeiro TF.   +10 more
europepmc   +1 more source

Regional corneal biomechanics assessment as a function of age using Strain–Stress Index maps

Ophthalmic and Physiological Optics, EarlyView.
Abstract Purpose To gain a better understanding of corneal Stress–Strain Index (SSI) maps in healthy eyes and to determine their changes with age. Method The eyes of 72 participants (age 43.1 ± 20.9 years, 69.5% female) were included in the analysis, considering the left and right eyes separately.
Vahoura Tahsini, Marta Jiménez‐García, Ahmed Makarem, Ahmed Elsheikh, Philippe Büchler, Sabine Kling, Jos J. Rozema   +6 more
wiley   +1 more source