Results 101 to 110 of about 44,199 (236)

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source

Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]

Journal of Kerman University of Medical Sciences, 2014
Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary, Sayedeh Zahra Bathaie, Fereshteh Bahmani, Gholamreza Moshtaghi Kashanian   +3 more
doaj  

Advanced glycation end products [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +3 more sources

1275‐nm Photobiomodulation Alleviates Brain Drainage Impairment as a Promising Therapeutic Strategy for Aging‐Related Neurological Decline

Aging Cell, EarlyView.
Noninvasive 1275‐nm photobiomodulation improves brain drainage and promotes lymphatic clearance of advanced glycation end products (AGEs) in an aging model (AM) in male mice. These effects are associated with nitric oxide release‐mediated dilation of meningeal lymphatic vessels (MLVs).
Hao Lin, Shaojun Liu, Qihang Yang, Junming Li, Jue Wang, Oxana Semyachkina‐Glushkovskaya, Dongyu Li, Tingting Yu, Dan Zhu   +8 more
wiley   +1 more source

Association between Moraxella keratitis and advanced glycation end products

Scientific Reports
Diabetes mellitus is recognized as a major predisposing factor for Moraxella keratitis. However, how diabetes mellitus contributes to Moraxella keratitis remains unclear.
Hidenori Inoue, Koji Toriyama, Naoko Takahira, Shinobu Murakami, Hitoshi Miyamoto, Takashi Suzuki, Atsushi Shiraishi   +6 more
doaj   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

The Anti-AGEing and RAGEing Potential of Isothiocyanates

Molecules
Isothiocyanates (ITCs), found in edible plants such as cruciferous vegetables, are a group of reactive organo-sulfur phytochemicals produced by the hydrolysis of precursors known as glucosinolates.
Bradley A. Krisanits, Bhoomika Kaur, Jed W. Fahey, David P. Turner   +3 more
doaj   +1 more source

Preparation of advanced glycation end products in vitro [PDF]

Nephrology Dialysis Transplantation, 2007
Casper G. Schalkwijk, Femke Waanders, Gerjan Navis, Harry van Goor, Else van den Berg   +4 more
openaire   +3 more sources

Complementary Predictors for Asthma Attack Prediction in Children: Salivary Microbiome, Serum Inflammatory Mediators, and Past Attack History

Allergy, EarlyView.
In this two‐phase study, school‐aged children were classified as at risk or no‐risk based on severe attacks during one‐year follow‐up. Four types of prediction models were developed. Salivary bacteria and serum inflammatory markers, while informative alone, complement past asthma attacks in predicting future attack risk.
Shahriyar Shahbazi Khamas, Paul Brinkman, Anne H. Neerincx, Susanne J. H. Vijverberg, Simone Hashimoto, Jelle M. Blankestijn, Jan Willem Duitman, Tamara Dekker, Barbara S. Smids, Suzanne W. J. Terheggen‐Lagro, René Lutter, Nariman K. A. Metwally, Fleur Sondaal, Eric G. Haarman, Peter J. Sterk, Ian M. Adcock, Charles Auffray, Corinna Bang, Aruna T. Bansal, Heike Buntrock‐Döpke, Klaus Bønnelykke, Andrew Bush, Bo Lund Chawes, Kian Fan Chung, Paula Corcuera‐Elosegui, Sven‐Erik Dahlén, Ratko Djukanovic, Louise J. Fleming, Stephen J. Fowler, Andre Franke, Urs Frey, Mario Gorenjak, Susanne Brandstetter, Susanne Harner, Gunilla Hedlin, Michael Kabesch, Nazanin Zounemat‐Kermani, Parastoo Kheirolldein, Alexander Kiefer, Jon R. Konradsen, Aletta D. Kraneveld, Leyre López‐Fernández, Clare S. Murray, Björn Nordlund, Maria Pino‐Yanes, Uroš Potočnik, Graham Roberts, Jakob Stokholm, Søren Johannes Sørensen, Olaia Sardón‐Prado, Dominick E. Shaw, Florian Singer, Ana R. Sousa, Jonathan Thorsen, Antoaneta A. Toncheva, Nadja H. Vissing, Christine Wolff, Mahmoud I. Abdel‐Aziz, Anke H. Maitland‐van der Zee, on behalf of the SysPharmPediA and U‐BIOPRED Consortia   +59 more
wiley   +1 more source

Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle, Linong Ji, Chantal Mathieu, Jonathan Rosen   +3 more
wiley   +1 more source