Results 11 to 20 of about 87,030 (164)

Advanced glycation end products, galectin-3, matrix metalloproteinase-9 activity in men with heart failure and concomitant benign prostatic hyperplasia with androgen deficiency

Medičnì Perspektivi, 2021
The aim was to evaluate serum levels of matrix metalloproteinases-9 activity, advanced glycation end products, galectin-3, C-reactive protein in men with heart failure and benign prostatic hyperplasiawith testosterone deficiency.
V.S. Nedzvetsky, O.Yu. Sirenko, V.A. Tkachenko, O.V. Kuryata   +3 more
doaj   +1 more source

Fingertip advanced glycation end products and psychotic symptoms among adolescents

npj Schizophrenia, 2021
Case control studies have suggested that advanced glycation end products play a key role in the pathophysiology of chronic schizophrenia. However, the longitudinal association between advanced glycation end products and psychotic symptoms among drug ...
Mitsuhiro Miyashita, Syudo Yamasaki, Shuntaro Ando, Kazuhiro Suzuki, Kazuya Toriumi, Yasue Horiuchi, Akane Yoshikawa, Atsushi Imai, Yukihiro Nagase, Yasuhiro Miyano, Tomoko Inoue, Kaori Endo, Yuko Morimoto, Masaya Morita, Tomoki Kiyono, Satoshi Usami, Yuji Okazaki, Toshiaki A. Furukawa, Mariko Hiraiwa-Hasegawa, Masanari Itokawa, Kiyoto Kasai, Atsushi Nishida, Makoto Arai   +22 more
doaj   +1 more source

Predictive ability of serum advanced glycation end products at 11 to 13 weeks of gestation for early-onset preeclampsiaAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD, Sho-ichi Yamagishi, MD, Takanori Matsui, PhD, Keiko Koide, MD, Hiroko Takita, MD, Mayumi Tokunaka, MD, Akihiko Sekizawa, MD   +6 more
doaj   +1 more source

Expression of advanced glycation end products and receptors in gingival tissues of patients with noninsulin-dependent diabetes mellitus-associated periodontitis

Journal of Dental Sciences, 2023
Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang, Chen-Ling Huang, An-Tsz Hsieh, Chia-Ai Jao, Hsein-Kun Lu   +4 more
doaj   +1 more source

NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification [PDF]

, 2005
The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to ...
Howard, Mark J., Smales, Christopher Mark   +1 more
core   +1 more source

Association of advanced glycation end products in Dupuytren disease

Journal of Orthopaedic Surgery and Research, 2018
Background Advanced glycation end products are associated with aging, hyperglycemia, and oxidative stress. Accumulation of advanced glycation end products can cause various pathological conditions; however, the association of Dupuytren’s disease with ...
Fumiaki Takase, Yutaka Mifune, Atsuyuki Inui, Yasuhiro Ueda, Takeshi Kataoka, Takeshi Kokubu, Ryosuke Kuroda   +6 more
doaj   +1 more source

Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts [PDF]

, 2019
Debilitating cases of tendon pain and degeneration affect the majority of diabetic individuals. The high rate of tendon degeneration persists even when glucose levels are well controlled, suggesting that other mechanisms may drive tendon degeneration in ...
Cannon, Jason R., Carroll, Chad C., Foguth, Rachel, Kuang, Shihuan, Patel, Shivam H., Sabbaghi, Arman, Saw, Shannon K., Shannahan, Jonathan H., Yue, Feng   +8 more
core   +2 more sources

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

PLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt   +9 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

Translational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner   +20 more
doaj   +1 more source

Advanced Glycation End Products in Health and Disease

Microorganisms, 2022
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy, Puspa Aryal, Emmanuel K. Darkwah   +2 more
doaj   +1 more source