Results 201 to 210 of about 8,152,704 (249)
Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang +9 more
wiley +1 more source
ABSTRACT Type 2 diabetes mellitus (T2DM) has increasingly been identified as a risk factor for sensorineural hearing loss, whereas the association between different antidiabetic therapies and hearing thresholds remains poorly characterized. This retrospective observational study evaluated 240 patients with T2DM and 105 normoglycemic controls who ...
Francesco Martines +8 more
wiley +1 more source
The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective
Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli +3 more
wiley +1 more source
Clinical recognition of the lipoedema phenotype and principal differential diagnoses. ABSTRACT Lipoedema is a painful adipose tissue disorder marked by disproportionate limb fat and often misclassified as generalized obesity or lymphoedema. This review examines its metabolic phenotype and implications for cardiometabolic assessment and management ...
Ron T. Varghese, Diana G. Varghese
wiley +1 more source
Consumer Perceptions of Glycation‐Induced Facial Skin Aging and the Role of Skincare Products
ABSTRACT Background Glycation is a biological process known to exacerbate undesirable skin aging parameters such as yellowing, dullness, wrinkles and reduced elasticity. This study aimed to better understand consumer perceptions of glycation on facial skin and consumer expectations of anti‐glycation skincare. Methods Focus group discussions (FGDs) with
Sharon Shi, Kelly Chua, Bee Leng Lua
wiley +1 more source
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Advanced glycation end products in uremia
Advances in Renal Replacement Therapy, 2003The term "advanced glycation end products" (AGEs) stands for a heterogeneous group of amino acid derivatives that are formed via glycation processes between peptide-bound lysine or arginine derivatives and carbonyl compounds, processes originally known from food systems as "Maillard reactions." AGEs accumulate in plasma and tissues with advancing age ...
Thomas, Henle, Toshio, Miyata
openaire +2 more sources
Advanced glycation and glycoxidation end products in bone
Bone, 2023Hyperglycemia and oxidative stress, enhanced in diabetes and aging, result in excessive accumulation of advanced glycation and glycoxidation end products (AGEs/AGOEs) in bone. AGEs/AGOES are considered to be "the missing link" in explaining increased skeletal fragility with diabetes, aging, and osteoporosis where increased fracture risk cannot be ...
Bowen, Wang, Deepak, Vashishth
openaire +2 more sources
Advanced glycation end products and the kidney
American Journal of Physiology-Renal Physiology, 2005Advanced glycation end products (AGEs) are a heterogeneous group of protein and lipids to which sugar residues are covalently bound. AGE formation is increased in situations with hyperglycemia (e.g., diabetes mellitus) and is also stimulated by oxidative stress, for example in uremia.
Jürgen M, Bohlender +3 more
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Dietary Advanced Glycation End Products and Aging [PDF]
Advanced glycation end products (AGEs) are a heterogeneous, complex group of compounds that are formed when reducing sugar reacts in a non-enzymatic way with amino acids in proteins and other macromolecules. This occurs both exogenously (in food) and endogenously (in humans) with greater concentrations found in older adults.
Claudia Luévano-Contreras
exaly +3 more sources
Advanced Glycation End Products and Diabetic Nephropathy
American Journal of Therapeutics, 2005Chronic hyperglycemia and oxidative stress in diabetes results in the formation and accumulation advanced glycation end products (AGEs). AGEs have a wide range of chemical, cellular, and tissue effects that contribute to the development of microvascular complications. In particular, AGEs appear to have a key role in the diabetic nephropathy.
Thomas, Merlin C. +2 more
openaire +3 more sources

