Results 61 to 70 of about 48,512 (351)

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

The association between dietary glycemic and insulin indices with incidence of cardiovascular disease: Tehran lipid and glucose study

BMC Public Health, 2020
Background The present study was conducted to investigate the association of dietary insulin index(II), insulin load(IL), glycemic index(GI), and glycemic load(GL) with the risk of cardiovascular disease(CVD).
Farshad Teymoori, Hossein Farhadnejad, Parvin Mirmiran, Milad Nazarzadeh, Fereidoun Azizi   +4 more
doaj   +1 more source

Glycemic Control and Acne: A Review [PDF]

International Journal of Nutrition Sciences, 2019
Acne as a chronic inflammation involves pilosebaceous unit and is associated with hyperkeratosis and sebaceous hypersecretion. A high glycemic index (GI) and glycemic load (GL) diet may stimulate acne proliferative pathways affecting biochemical factors ...
Zahra Setavand, Maryam Ekramzadeh
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Acute effect of meal glycemic index and glycemic load on blood glucose and insulin responses in humans

Nutrition Journal, 2006
Objective Foods with contrasting glycemic index when incorporated into a meal, are able to differentially modify glycemia and insulinemia. However, little is known about whether this is dependent on the size of the meal.
Díaz Erik, Aguirre Carolina, Galgani José   +2 more
doaj   +1 more source

Metabolic effects of diets differing in glycaemic index depend on age and endogenous GIP [PDF]

, 2009
Aims/hypothesis High- vs low-glycaemic index (GI) diets unfavourably affect body fat mass and metabolic markers in rodents. Different effects of these diets could be age-dependent, as well as mediated, in part, by carbohydrate-induced stimulation of ...
A. Abdelrahman, A. F. Pfeiffer, AR Josse, AW Barclay, B. Thorens, C Yamada, C Zhang, Coon PJ, Rogus EM, Drinkwater D, Muller DC, Goldberg AP, DB Pawlak, DB Pawlak, DS Ludwig, DW Foster, EM Schothorst van, EO Diaz, F Isken, F Isken, F Preitner, F. Isken, J Brand-Miller, J Salmeron, J Salmeron, J Stevens, JA Marshall, JJ Holst, JJ Meier, K Miyawaki, KA Meyer, KB Scribner, KB Scribner, KH Ding, M Kabir, M Lerer-Metzger, M. H. Tschöp, M. Möhlig, M. O. Weickert, MB Schulze, MK Hellerstein, MO Weickert, R. Nogueiras, RM Dam van, S Liu, S. Klaus, SE Byrnes, SJ Gatenby, WM Kohrt, X Pi-Sunyer   +45 more
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Glycemic index and glycemic load are associated with some cardiovascular risk factors among the PREMIER study participants

Food & Nutrition Research, 2012
Background: The clinical significance of glycemic index (GI) and glycemic load (GL) is inconclusive. Objective : This study was conducted to examine the association of GI and GL with clinical cardiovascular disease (CVD) risk factors including body ...
Pao-Hwa Lin, Chuhe Chen, Deborah R. Young, Diane Mitchell, Patricia Elmer, Yanfang Wang, Bryan Batch, Catherine Champagne   +7 more
doaj   +1 more source

Nutritional factors associated with acne vulgaris [PDF]

, 2016
Acne Vulgaris is a common dermatological condition defined as a chronic inflammatory dermatosis of the pilosebaceous unit that affects more than 17 million Americans.^1 Although it is not considered a dangerous condition, it may drastically impair ...
Patton, Elaura Elizabeth
core   +1 more source

Nutritional modulation of insulin resistance [PDF]

, 2012
Insulin resistance has been proposed as the strongest single predictor for the development of Type 2 Diabetes (T2DM). Chronic oversupply of energy from food, together with inadequate physical activity, have been recognized as the most relevant factors ...
Weickert, Martin O.
core   +3 more sources