Results 21 to 30 of about 16,159 (210)

Three-dimensional enhanced lipidomics analysis combining UPLC, differential ion mobility spectrometry, and mass spectrometric separation strategies1[S]

Journal of Lipid Research, 2014
Phospholipids serve as central structural components in cellular membranes and as potent mediators in numerous signaling pathways. There are six main classes of naturally occurring phospholipids distinguished by their distinct polar head groups that ...
Paul R.S. Baker, Aaron M. Armando, J. Larry Campbell, Oswald Quehenberger, Edward A. Dennis   +4 more
doaj   +1 more source

The Effects of Consuming White Button Mushroom Agaricus bisporus on the Brain and Liver Metabolome Using a Targeted Metabolomic Analysis

Metabolites, 2021
A targeted metabolomic analysis was performed on tissues derived from pigs fed diets supplemented with white button mushrooms (WBM) to determine the effect on the liver and brain metabolome.
Gloria I. Solano-Aguilar, Sukla Lakshman, Saebyeol Jang, Richi Gupta, Aleksey Molokin, Steven G. Schroeder, Patrick M. Gillevet, Joseph F. Urban   +7 more
doaj   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

Angewandte Chemie, EarlyView.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang, Jesse A. Michael, Jonathan D. Teo, Huitong Song, Mika T. Westerhausen, Shadrack M. Mutuku, Shane R. Ellis, Anthony S. Don   +7 more
wiley   +2 more sources

Human phospholipases A2: a functional and evolutionary analysis

Вавиловский журнал генетики и селекции, 2023
Phospholipases A2 (PLA2) are capable of hydrolyzing the sn-2 position of glycerophospholipids to release fatty acids and lysophospholipids. The PLA2 superfamily enzymes are widespread and present in most mammalian cells and tissues, regulating metabolism,
I. I. Turnaev, M. E. Bocharnikova, D. A. Afonnikov   +2 more
doaj   +1 more source

Lactose-Derived Carbohydrates Induce Sexually Dimorphic Nutritional Programming Effects on Lifespan in Drosophila melanogaster. [PDF]

Aging Cell
Early‐life co‐consumption of galactose and glucose (hydrolyzed lactose) programs Drosophila melanogaster lifespan in a sex‐specific manner. Particularly, the co‐consumption of galactose and glucose programs extended lifespan when female flies were challenged by obesogenic diets later in life, and this is concomitant with remodeling of lipid metabolism,
Sun P, Shao S, Creemers RW, Bekebrede AF, Tang J, Driever S, Keijer J, van Schothorst EM.   +7 more
europepmc   +2 more sources

glycerophospholipid [PDF]

, 2014
Citation: 'glycerophospholipid' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02648 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

Journal of Lipid Research, 2020
A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS classification system and shorthand notation of lipid structures
Gerhard Liebisch, Eoin Fahy, Junken Aoki, Edward A. Dennis, Thierry Durand, Christer S. Ejsing, Maria Fedorova, Ivo Feussner, William J. Griffiths, Harald Köfeler, Alfred H. Merrill, Jr., Robert C. Murphy, Valerie B. O'Donnell, Olga Oskolkova, Shankar Subramaniam, Michael J.O. Wakelam, Friedrich Spener   +16 more
doaj   +1 more source

PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids

Journal of Lipid Research, 2020
The plasma membrane of neurons consists of distinct domains, each of which carries specialized functions and a characteristic set of membrane proteins.
Hideaki Kuge, Izumi Miyamoto, Ken-ichi Yagyu, Koichi Honke   +3 more
doaj   +1 more source

HPLC–(Q)-TOF-MS-Based Study of Plasma Metabolic Profile Differences Associated with Age in Pediatric Population Using an Animal Model

Metabolites, 2022
A deep knowledge about the biological development of children is essential for appropriate drug administration and dosage in pediatrics. In this sense, the best approximation to study organ maturation is the analysis of tissue samples, but it requires ...
Oihane E. Albóniga, Oskar González-Mendia, María E. Blanco, Rosa M. Alonso   +3 more
doaj   +1 more source

GPs’ experiences of phosphatidylethanol in treatment of hypertension: a qualitative study

BJGP Open, 2023
Background: Hazardous alcohol use increases the risk of hypertension but is underdetected in primary healthcare (PHC) patients. Use of the biomarker phosphatidylethanol (PEth), which reflects the last 2–3 weeks of alcohol consumption, is increasing in ...
Åsa Thurfjell, Christina Sandlund, Johanna Adami, Jan Hasselström, Maria Hagströmer, Lena Lundh   +5 more
doaj   +1 more source