Results 41 to 50 of about 21,259 (271)

Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity

open access: yes, 2022
Nine mammalian adenylyl cyclases (AC) are pseudoheterodimers with two hexahelical membrane domains, which are isoform-specifically conserved. Previously we proposed that these membrane domains are orphan receptors (https://doi.org/10.7554/eLife.13098 ...
Seth, A.   +15 more
core   +2 more sources

glycerophospholipid [PDF]

open access: yes, 2014
Citation: 'glycerophospholipid' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02648 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Analysis of Glycerophospholipids.

open access: yes, 2014
Glycerophospholipids were detected by LC-MS/MS in negative ionization mode: (a) 1-arachidonoylglycerophosphoinositol (patient/control ratio:2.4 ...
Edward D. Karoly (493683)   +7 more
core   +1 more source

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]

open access: yes, 2012
Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko (144194)   +39 more
core   +2 more sources

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

open access: yesAdvanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang   +6 more
wiley   +1 more source

Optimized 13C-TrEnDi enhances the sensitivity of plasmenyl ether glycerophospholipids and demonstrates compatibility with other derivatization strategies [PDF]

open access: yes
The identification and quantitation of plasmalogen glycerophospholipids is challenging due to their isobaric overlap with plasmanyl ether-linked glycerophospholipids, susceptibility to acid degradation, and their typically low abundance in biological ...
Samuel, Shields   +7 more
core   +2 more sources

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

open access: yesAdvanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong   +9 more
wiley   +1 more source

Detection of the Disorders of Glycerophospholipids and Amino Acids Metabolism in Lung Tissue From Male COPD Patients

open access: yesFrontiers in Molecular Biosciences, 2022
Background: At present, few studies have reported the metabolic profiles of lung tissue in patients with COPD. Our study attempted to analyze the lung metabolome in male COPD patients and to screen the overlapping biomarkers of the lung and plasma ...
Qian Huang   +9 more
doaj   +1 more source

Composition of glycerophospholipids from the hydrocorals Millepora platyphylla and M. dichotoma.

open access: yes, 2019
Composition of glycerophospholipids from the hydrocorals Millepora platyphylla and M. dichotoma.
Andrey B. Imbs (6645782)   +2 more
core   +1 more source

Image5_Plasmalogens, the Vinyl Ether-Linked Glycerophospholipids, Enhance Learning and Memory by Regulating Brain-Derived Neurotrophic Factor.TIF

open access: yes, 2022
Plasmalogens (Pls), a kind of glycerophospholipids, have shown potent biological effects but their role in hippocampus-dependent memory remained mostly elusive.
Shiro Mawatari (12062999)   +2 more
core   +1 more source

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