Results 21 to 30 of about 20,599 (278)

Asymmetric glycerophospholipids impart distinctive biophysical properties to lipid bilayers

, 2021
Phospholipids are a diverse group of biomolecules consisting of a hydrophilic headgroup and two hydrophobic acyl tails. The nature of the head and length and saturation of the acyl tails are important for defining the biophysical properties of lipid ...
Makarova, Maria, Smith, Paul, Lorenz, Christian D., Owen, Dylan M., Lorenz, Christian D.; id_orcid   +4 more
core   +1 more source

Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity

, 2022
Nine mammalian adenylyl cyclases (AC) are pseudoheterodimers with two hexahelical membrane domains, which are isoform-specifically conserved. Previously we proposed that these membrane domains are orphan receptors (https://doi.org/10.7554/eLife.13098 ...
Seth, A., Elsabbagh, S. ; https://orcid.org/, Landau, M. ; https://orcid.org/, Schultz, A., Shevchenko, A., Schultz, J.   +5 more
core   +2 more sources

High-throughput analysis of fatty acid composition of plasma glycerophospholipids[S]

Journal of Lipid Research, 2010
Plasma FA composition, a marker of FA status and dietary intake, is associated with health outcomes on a short- and long-term basis. Detailed investigation of the relationships between plasma FA composition and health requires the analysis of large ...
Claudia Glaser, Hans Demmelmair, Berthold Koletzko   +2 more
doaj   +1 more source

The Acinetobacter baumannii Mla system and glycerophospholipid transport to the outer membrane

eLife, 2019
The outer membrane (OM) of Gram-negative bacteria serves as a selective permeability barrier that allows entry of essential nutrients while excluding toxic compounds, including antibiotics.
Cassandra Kamischke, Junping Fan, Julien Bergeron, Hemantha D Kulasekara, Zachary D Dalebroux, Anika Burrell, Justin M Kollman, Samuel I Miller   +7 more
doaj   +1 more source

Chemical Biology Tools to Study Lipids and their Metabolism with Increased Spatial and Temporal Resolution

CHIMIA, 2021
Lipids are important cellular components providing many essential functions. To fulfill these various functions evolution has selected for a diverse set of lipids and this diversity is seen at the organismal, cellular and subcellular level ...
Clémence Simon, Suihan Feng, Howard Riezman   +2 more
doaj   +1 more source

Biosynthesis of acyl-specific glycerophospholipids in mammalian tissues Postulation of new pathways [PDF]

, 1984
A review of the literature concerning the synthesis of acyl-specific glycerophospholipids indicates that the known biosynthetic sequences cannot satisfactorily explain these specific acylations.
Juan P. Infante, Infante, Juan P.
core   +1 more source

Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin[S]

Journal of Lipid Research, 2010
We examined the effect of the cellular sphingolipid level on the release of arachidonic acid (AA) and activity of cytosolic phospholipase A2α (cPLA2α) using two Chinese hamster ovary (CHO)-K1-derived mutants deficient in sphingolipid synthesis: LY-B ...
Hiroyuki Nakamura, Shigeo Wakita, Akiko Suganami, Yutaka Tamura, Kentaro Hanada, Toshihiko Murayama   +5 more
doaj   +1 more source

Marine Plasmalogens: A Gift from the Sea with Benefits for Age-Associated Diseases

Molecules, 2023
Aging increases oxidative and inflammatory stress caused by a reduction in metabolism and clearance, thus leading to the development of age-associated diseases. The quality of our daily diet and exercise is important for the prevention of these diseases.
Shinji Yamashita, Taiki Miyazawa, Ohki Higuchi, Mikio Kinoshita, Teruo Miyazawa   +4 more
doaj   +1 more source

Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry[S]

Journal of Lipid Research, 2009
Glycerophospholipid and sphingolipid species and their bioactive metabolites are important regulators of lipoprotein and cell function. The aim of the study was to develop a method for lipid species profiling of separated lipoprotein classes. Human serum
Philipp Wiesner, Katharina Leidl, Alfred Boettcher, Gerd Schmitz, Gerhard Liebisch   +4 more
doaj   +1 more source

Effects of a 12-week whole-grain or refined wheat intervention on plasma acylcarnitines, bile acids and signaling lipids, and association with liver fat: A post-hoc metabolomics study of a randomized controlled trial

Frontiers in Nutrition, 2022
BackgroundWe previously showed that whole-grain wheat (WGW) consumption had beneficial effects on liver fat accumulation, as compared to refined wheat (RW).
Anouk Gijbels, Sophie Schutte, Diederik Esser, Suzan Wopereis, Gerard Bryan Gonzales, Lydia A. Afman   +5 more
doaj   +1 more source