Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]
Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel +2 more
core +1 more source
The phospholipids from murine mastocytoma FMA3 and P-815 clone cells were quantitatively analyzed, and the major glycerophospholipids were examined for their fatty acyl chain distribution.
S Yoshioka +5 more
doaj +1 more source
Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Glycerophospholipids consist of a glycerophosphate backbone to which are esterified two acyl chains and a polar head group. The head group (e.g., choline, ethanolamine, serine or inositol) defines the glycerophospholipid class, while the acyl chains ...
Satu Hänninen +2 more
doaj +1 more source
The effect of temperature on glyceryl ethers in Tetrahymena pyriformis W
The effect of temperature on the ether content of the glycerophospholipids of Tetrahymena pyriformis W was examined. The only ether detected was 1-O-hexadecyl glycerol (alpha-chimyl alcohol).
S Lund-Katz, R L Conner
doaj +1 more source
The Various Roles of Fatty Acids
Lipids comprise a large group of chemically heterogeneous compounds. The majority have fatty acids (FA) as part of their structure, making these compounds suitable tools to examine processes raging from cellular to macroscopic levels of organization ...
Carla C. C. R. de Carvalho +1 more
doaj +1 more source
Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua +14 more
core +1 more source
Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli
Rapid dissemination of the plasmid-born polymyxin resistance gene mcr-1 poses a critical medical challenge. MCR-1 expression is tightly controlled and imposes a fitness cost on the bacteria.
Yi-Yun Liu +15 more
doaj +1 more source
Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts
A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS).
Barsch, A. +8 more
core +1 more source
Chlamydial infection from outside to inside [PDF]
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke +2 more
core +2 more sources
High-throughput analysis of fatty acid composition of plasma glycerophospholipids[S]
Plasma FA composition, a marker of FA status and dietary intake, is associated with health outcomes on a short- and long-term basis. Detailed investigation of the relationships between plasma FA composition and health requires the analysis of large ...
Claudia Glaser +2 more
doaj +1 more source

