Results 111 to 120 of about 780,935 (307)

Methanol extract of Nigella sativa seed induces changes in the levels of neurotransmitter amino acids in male rat brain regions

open access: yesPharmaceutical Biology, 2017
Context: Nigella sativa L. (Ranunculaceae) (NS) has been used for medicinal and culinary purposes. Different parts of the plant are used to treat many disorders.
Tarek El-Naggar   +3 more
doaj   +1 more source

Chiral Microneedle Arrays With Terahertz Chiroptical Activity With Chiral‐Plasmon‐Chiral‐Phonon Resonance

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub‐millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the terahertz (THz) spectral window.
Sang Hyun Lee   +6 more
wiley   +1 more source

Bilateral and symmetric glycinergic and glutamatergic projections from the LSO to the IC in the CBA/CaH mouse

open access: yesFrontiers in Neural Circuits
Auditory space has been conceptualized as a matrix of systematically arranged combinations of binaural disparity cues that arise in the superior olivary complex (SOC).
Isabella R. Williams   +4 more
doaj   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

open access: yesAdvanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross   +3 more
wiley   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi   +3 more
wiley   +1 more source

Cycloid psychoses in the psychosis spectrum: evidence for biochemical differences with schizophrenia

open access: yesNeuropsychiatric Disease and Treatment, 2016
Nora WA van de Kerkhof,1,2 Durk Fekkes,2,3 Frank MMA van der Heijden,1 Witte JG Hoogendijk,2 Gerald Stöber,4 Jos IM Egger,1,5,6 Willem MA Verhoeven1,2 1Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray,
van de Kerkhof N   +6 more
doaj  

Sustainable Soil Additives for Water and Micronutrient Supply: Swelling and Chelating Properties of Polyaspartic Acid Hydrogels Utilizing Newly Developed Crosslinkers

open access: yesGels
Drought and water shortage are serious problems in many arid and semi-arid regions. This problem is getting worse and even continues in temperate climatic regions due to climate change.
Youssef Hafidi   +6 more
doaj   +1 more source

De Novo Autogenic Engineered Living Functional Materials

open access: yesAdvanced Materials, EarlyView.
A versatile platform for de novo autogenic engineered living materials is presented, leveraging protein mining, computational modeling, and synthetic biology. By reprogramming the Escherichia coli curli machinery with β‐solenoid proteins from non‐model bacteria, macroscopic biomaterials with enhanced mechanical properties, UV‐C irradiation protection ...
Hoda M. Hammad   +9 more
wiley   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

open access: yesAdvanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi   +5 more
wiley   +1 more source

Nuclear Pore Mechanotransduction in Oncology: A Structural Axis of Vulnerability for Targeted Intervention

open access: yesAdvanced Materials, EarlyView.
Cancer‐associated NPC remodeling creates a high‐flux, low‐stringency nuclear state that supports malignant adaptation but increases mechanical fragility. Targeting the FG‐barrier or NPC scaffold may drive mechanostat failure, envelope rupture, DNA damage, and loss of nuclear integrity.
Sílvio Terra Stefanello   +5 more
wiley   +1 more source

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