Results 121 to 130 of about 43,679 (304)
MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis
Advanced Science, EarlyView.This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang +18 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, 2020 Sepsis is a multifactorial syndrome primarily determined by the host response to an invading pathogen. It is common, with over 48 million cases worldwide in 2017, and often lethal.
F. Lupu, G. Kinasewitz, K. Dormer
semanticscholar +1 more source
Microcirculatory blood flow: Functional implications of a complex fluid [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011) +3 more
core
Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
core +2 more sources
Animal Research and One Health, EarlyView.This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao +6 more
wiley +1 more source
Sublingual endothelial glycocalyx and atherosclerosis. A cross-sectional study.
PLoS ONE, 2019 BACKGROUND:Damage to endothelial glycocalyx is thought to be an early marker of atherosclerosis and measuring reduced glycocalyx size clinically via the Perfused Boundary Region (PBR) may allow early detection of cardiovascular disease. However, the true
Luca Valerio +3 more
doaj +1 more source
Wall shear stress and arterial performance: two approaches based on engineering [PDF]
, 2009 This is the Abstract of the Article. Copyright @ 2009 Oxford University.This crucially important subject generates a very wide literature and the recent authoritative ‘in vivo’ review of Reneman et al [1] (& [2]), with Vennemann et al [3], are taken as ...
Atherton, MA, Collins, MW, Koenig, CS
core
Three-dimensional low Reynolds number flows near biological filtering and protective layers
, 2017 Mesoscale filtering and protective layers are replete throughout the natural world. Within the body, arrays of extracellular proteins, microvilli, and cilia can act as both protective layers and mechanosensors.
Battista, Nicholas A. +5 more
core +1 more source
Vascular Endothelial Glycocalyx Damage in COVID-19
International Journal of Molecular Sciences, 2020 The new coronavirus disease-2019 (COVID-19), which is spreading around the world and threatening people, is easily infecting a large number of people through airborne droplets; moreover, patients with hypertension, diabetes, obesity, and cardiovascular ...
M. Yamaoka-Tojo
semanticscholar +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher +12 more
wiley +1 more source