Results 41 to 50 of about 43,679 (304)
Comprehensive Physiology, 2022 The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is primarily conformed of glycoproteins and proteoglycans, which provide communication, electrostatic charge, ionic buffering, permeability, and mechanosensation ...
Christopher A. Foote +7 more
semanticscholar +1 more source
Surface wave excitations and backflow effect over dense polymer brushes [PDF]
, 2016 Polymer brushes are being increasingly used to tailor surface physicochemistry for diverse applications such as wetting, adhesion of biological objects, implantable devices and much more.
BIAGI, SOFIA +3 more
core +3 more sources
Visualising the endothelial glycocalyx in dogs
The Veterinary Journal, 2022 The endothelial glycocalyx (eGlx) lines the luminal surface of endothelial cells. It is critical in maintaining vascular health and when damaged contributes to many diseases. Its fragility makes studying the eGlx technically challenging. The current reference standard for eGlx visualisation, by electron microscopy using glutaraldehyde/Alcian blue ...
Lawrence-Mills, Sara +5 more
openaire +4 more sources
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
, 2008 A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Becker, Bernhard F. +6 more
core +1 more source
Vascular Endothelial Glycocalyx Damage and Potential Targeted Therapy in COVID-19
Cells, 2022 COVID-19 is a highly infectious respiratory disease caused by a new coronavirus known as SARS-CoV-2. COVID-19 is characterized by progressive respiratory failure resulting from diffuse alveolar damage, inflammatory infiltrates, endotheliitis, and ...
Duoduo Zha, M. Fu, Yisong Qian
semanticscholar +1 more source
PLOS ONE, 2021 Pathological hyperpermeability is a morbidity involved in various systemic diseases, including sepsis. The endothelial glycocalyx layer (GCX) plays a key role in controlling vascular permeability and could be a useful therapeutic target. The purpose of the present study was to analyze the functional role of the GCX in vascular permeability and to ...
Takehiko Iijima +3 more
openaire +5 more sources
Mediators of Inflammation, 2023 This review aims at summarizing state-of-the-art knowledge on glycocalyx and SARS-CoV-2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane-bound proteoglycans and glycoproteins.
Bingxuan Lv +4 more
doaj +1 more source
Resuscitation fluids as drugs: targeting the endothelial glycocalyx
Chinese Medical Journal, 2022 . Fluid resuscitation is an essential intervention in critically ill patients, and its ultimate goal is to restore tissue perfusion. Critical illnesses are often accompanied by glycocalyx degradation caused by inflammatory reactions, hypoperfusion, shock,
Guangjian Wang +5 more
doaj +1 more source
Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]
, 2010 Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki +5 more
core +1 more source
Perioperative implication of the endothelial glycocalyx [PDF]
Korean Journal of Anesthesiology, 2018 The endothelial glycocalyx (EG) is a gel-like layer lining the luminal surface of healthy vascular endothelium. Recently, the EG has gained extensive interest as a crucial regulator of endothelial funtction, including vascular permeability, mechanotransduction, and the interaction between endothelial and circulating blood cells.
Jong Wook Song, Michael S. Goligorsky
openaire +5 more sources