Results 61 to 70 of about 6,575 (136)

Sepsis-induced endothelial glycocalyx disruption and remodeling: an ultrastructural study in mice

Intensive Care Medicine Experimental
Background Sepsis damages endothelial cells through glycocalyx degradation, contributing to organ dysfunction. Glycocalyx repair is essential for recovery, but the underlying mechanisms remain unclear. Rhamnan sulfate (RS), a sulfated polysaccharide with
Ryo Hisamune, Kazuma Yamakawa, Hong Wu, Yoshihiko Fujioka, Katsuhide Kayano, Noritaka Ushio, Rintaro Oide, Masahiro Terasawa, Koji Suzuki, Takashi Nakano, Akira Takasu   +10 more
doaj   +1 more source

Mapping the Intellectual Structure of AI‐Driven ESG Cost Modeling: A Bibliometric Analysis of Trends, Themes, and Future Directions

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The bibliometric and qualitative analyses of 470 publications in the Web of Science Core Collection from 2004 through 2025 in this study associated the intellectual structure and thematic evolution of AI‐driven ESG cost modeling. The research commences using an integrated analytical framework consisting of three tools: (1) Bibliometrix (R) for
Nesreen Al‐Malkawi, Adriana Giret
wiley   +1 more source

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher, Kensuke Matsushita, Shinnosuke Kikuchi, Taraneh Tatarcheh, Benjamin Marchandot, Amandine Granier, Said Amissi, Antonin Trimaille, Laurence Jesel, Patrick Ohlmann, Kiyoshi Hibi, Valérie Schini‐Kerth, Olivier Morel   +12 more
wiley   +1 more source

DataSheet1_Tetramethylpyrazine Alleviates Endothelial Glycocalyx Degradation and Promotes Glycocalyx Restoration via TLR4/NF-κB/HPSE1 Signaling Pathway During Inflammation.docx

, 2022
Tetramethylpyrazine (TMP), a Chinese traditional herbal extraction widely used in treating cardiovascular diseases, could attenuate vascular endothelial injuries, but the underlying mechanism remains incomprehensive.
Jun Zhang (48506), Jin Lei (7294613), Tingting Wang (123983), Le Chen (1446445), Lei Zhang (38117), Peng Xiang (2360800), Wanping Zhang (12036743), Issa Issoufou Ibrahim (10658516), Shengmei Zeng (12036740), Limei Ma (438710), Chao Yu (562804), Ruihong Yu (10678476), Zhiyi Yuan (9198904)   +12 more
core   +1 more source

Sirtuin 1 and endothelial glycocalyx [PDF]

, 2020
Sirtuin1 deficiency or reduced activity comprises one of the hallmarks of diseases as diverse as chronic cardiovascular, renal, and metabolic, some malignancies, and infections, as well as aging-associated diseases.
송종욱, Song, Jong Wook, Song, Jong Wook; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, South Korea, Goligorsky, Michael S, Lipphardt, Mark; Department of Nephrology and Rheumatology, Göttingen University Medical Center, Georg August University, Göttingen, Germany, Lipphardt, Mark, Goligorsky, Michael S; Renal Research Institute, New York Medical College at the Touro University, Valhalla, USA   +6 more
core   +1 more source

Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis

Respiratory Research, 2022
Highlights It is the first time to prove the confirm the endothelial glycocalyx impairment in COPD. FGF10 attenuates the development of emphysema and the shedding of glycocalyx induced by CSE in vivo.
Tian Jiang, Weiping Hu, Shaoyuan Zhang, Changhao Ren, Siyun Lin, Zhenyu Zhou, Hao Wu, Jun Yin, Lijie Tan   +8 more
doaj   +1 more source

Non‐Linear Threshold Effect of Dynamic Estimated Plasma Volume Status on Revealing In‐Hospital Mortality Risk in Sepsis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study evaluated the association between estimated plasma volume status (ePVS) and in‐hospital mortality in adult patients with sepsis from the MIMIC‐IV (v2.2) database. After excluding patients with early death, readmission, red blood cell transfusion, malignancy, or missing ePVS data, 17,403 patients meeting Sepsis‐3
Zhi‐An Si, Sheng‐Bing Xia, Yang Zou, Xiao‐Yan Wang   +3 more
wiley   +1 more source

Comparison of endothelial glycocalyx staining intensity.

, 2021
IL-22:Fc treated mice have improved preservation of the endothelial glycocalyx in alveolar capillaries as compared to sham animals. Endothelial glycocalyx staining intensity was increased in the alveolar capillaries in IL-22:Fc treated mice after low ...
Alanna Wanek (11512968), Olan Jackson-Weaver (11512962), Robert Drury (11512971), Aaron Cotton-Betteridge (11512977), Sarah Abdullah (11512965), Juan Duchesne (11512980), Derek Pociask (11512983), Sharven Taghavi (11512959), Jacob Packer (11512974), Jay Kolls (11512986)   +9 more
core   +1 more source

Application of Organic Superabsorbent Cellulosic Polymers (OSCPs) and Cyanobacteria on Reduction of Aeolian Losses

Land Degradation &Development, EarlyView.
ABSTRACT Establishing biocrusts on sandy surfaces in harsh desert environments presents significant challenges due to extreme ecological conditions. To address these challenges, this study examined the effects of two organic superabsorbent cellulosic polymers (OSCPs)—carboxymethyl cellulose (CMC) and guar gum (GUA)—on the establishment of ...
Leila Kashi Zenouzi, Ahmad Asgharzadeh, Federico Rossi, Mohammad Khosroshahi, Seyed Hassan Kaboli   +4 more
wiley   +1 more source

Glycocalyx in Endotoxemia and Sepsis

, 2020
Along with the recognition of a crucial role played by endothelial dysfunction secondarily igniting cardiovascular, pulmonary, and renal complications, investigational focus has extended toward endothelial glycocalyx.
Goligorsky, Michael S., Sun, Dong
core   +1 more source