Results 81 to 90 of about 6,575 (136)
BiomedicinesBackground/Objective: The endothelial glycocalyx is a gel-like layer on the vascular endothelial surface that is crucial for maintaining vascular homeostasis.
Aya Kimura +7 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
Diabetic Medicine, EarlyView.Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo +4 more
wiley +1 more source
Glycocalyx shedding by T. regenti cercaria after stimulation with JAC lectin.
, 2017 (A) anterior half of cercarial body shed the glycocalyx. (B) a ring of glycocalyx with bound lectin was shed from the anterior part of body and rolled over the posterior part and the tail stem.
Libor Mikeš (849776) +4 more
core +1 more source
The FEBS Journal, EarlyView.Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source
The FEBS Journal, EarlyView.Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns +11 more
wiley +1 more source
The FEBS Journal, EarlyView.This study reveals that changes in the electrical charge, that is zeta potential of large extracellular vesicles (uEVs) found in urine, can reflect disease progression from diabetes to kidney scarring (fibrosis). With further clinical development, measurement of uEVs charge could provide a simple, noninvasive way to monitor disease progression and help
Melanie Tepuš +6 more
wiley +1 more source
Assessment and Imaging of the Cerebrovascular Glycocalyx
, 2016 The glycocalyx is a gel-like layer lining the luminal surface of the endothelium. The glycocalyx exerts an important barrier role because it prevents exposure of plasma components to the endothelial surface.
Rijkers, Kim +7 more
core +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov +3 more
wiley +1 more source
Journal of Microscopy, EarlyView.Abstract AFM is not for the faint of heart. It has never been for these 40 years since its invention or for any of the modalities that have emerged. And among them, the initial concept of using AFM to measure cell mechanics was simply brazen. On the one hand, those pioneers hacked an imaging tool optimised for minimal mechanical interaction between ...
Núria Gavara
wiley +1 more source