Results 71 to 80 of about 7,626 (185)

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau, Maxime Riberaud, Frédéric Taran, Antoine Sallustrau   +3 more
wiley   +1 more source

Functional Heterogeneity of the Autism Spectrum Disorder‐Associated Gut Microbial Ecosystem Revealed by Fecal Lipopolysaccharides and Bacterial Proteomic Profiling

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
Gut microbiota associated with pediatric autism spectrum disorder exhibit functional heterogeneity characterized by altered fecal lipopolysaccharide landscapes, metabolic remodeling, and enhanced microglial inflammatory responses despite largely preserved microbial composition.
Stefania De Chiara, Angela Di Somma, Valentina Mazziotti, Serena Coppola, Franca Oglio, Lidia Tammaro, Maria Pia Riccio, Carmela Bravaccio, Antonio Molinaro, Roberto Berni Canani, Flaviana Di Lorenzo   +10 more
wiley   +1 more source

Synthesis of S‐Linked Glycoconjugates of Monosaccharides and Levoglucosenone Derivatives Through Photoinduced Thiol–Ene Reaction Mediated by 4CzIPN and Its Water Soluble Analog

European Journal of Organic Chemistry, Volume 29, Issue 38, 13 October 2026.
Visible‐light thiol–ene reaction mediated by 4CzIPN enables access to hydrolytically stable S‐linked glycoconjugates from levoglucosenone‐derived thiols (Y = 91% to quant. d.r. = up to >95:5) and conventional thio‐sugars (Y = 80% to quant. d.r. = up to >95:5).
Lorenzo Poletti, Francesco Riina, Daniele Ragno, Carmela De Risi, Alessandro Massi, Graziano Di Carmine   +5 more
wiley   +1 more source

Neoglycoconjugate of Tetrasaccharide Representing One Repeating Unit of the Streptococcus pneumoniae Type 14 Capsular Polysaccharide Induces the Production of Opsonizing IgG1 Antibodies and Possesses the Highest Protective Activity As Compared to Hexa- and Octasaccharide Conjugates

Frontiers in Immunology, 2017
Identifying protective synthetic oligosaccharide (OS) epitopes of Streptococcus pneumoniae capsular polysaccharides (CPs) is an indispensable step in the development of third-generation carbohydrate pneumococcal vaccines.
Ekaterina A. Kurbatova, Nelli K. Akhmatova, Elina A. Akhmatova, Nadezhda B. Egorova, Natalya E. Yastrebova, Elena V. Sukhova, Dmitriy V. Yashunsky, Yury E. Tsvetkov, Marina L. Gening, Nikolay E. Nifantiev   +9 more
doaj   +1 more source

Towards Understanding the Role of the Glycosylation of Proteins Present in Extracellular Vesicles in Urinary Tract Diseases: Contributions to Cancer and Beyond

Molecules
Extracellular vesicles (EVs) are a population of nanoscale particles surrounded by a phospholipid bilayer, enabling intercellular transfer of bioactive molecules.
Magdalena Wilczak, Magdalena Surman, Małgorzata Przybyło   +2 more
doaj   +1 more source

glycoconjugate

, 2014
Citation: 'glycoconjugate' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02651 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Analysis of immunogenicity and purification methods in conjugated polysaccharide vaccines: a new approach in fighting pathogenic bacteria

Frontiers in Immunology
Carbohydrates are commonly found in conjunction with lipids or proteins, resulting in the formation of glycoconjugates such as glycoproteins, glycolipids, and proteoglycans.
Arya Sheikhi, Arya Sheikhi, Mina Shirmohammadpour, Mina Shirmohammadpour, Nima Mahdei Nasirmahalleh, Bahman Mirzaei   +5 more
doaj   +1 more source

Development and Protective Evaluation of an O18-CRM197 Glycoconjugate Candidate Preparation Against APEC O18 Challenge in SPF Chickens. [PDF]

Microorganisms
Zhu T, Yuan J, Feng K, Bai H, Yan C, Yang Y, Qin A, Jin W.   +7 more
europepmc   +1 more source

Extracellular matrix: understanding the complexity [PDF]

Brazilian Journal of Medical and Biological Research, 1999
R. Borojevic
doaj   +1 more source

Synthetic PS-III Glycoconjugate Vaccines Based on Solid-Phase Assembled Well-Defined Oligosaccharides Confers Protection against <i>Clostridium difficile</i>. [PDF]

ACS Cent Sci
Chen Y, Liu X, Zhang T, Wang Z, Li Y, Zeng J, Li H, Zong C, Liu Q.   +8 more
europepmc   +1 more source