Results 61 to 70 of about 2,336 (164)

Group B Streptococcus (GBS) Carriage in Pregnant Women: Possible Emergence of Rare Serotypes and Antibiotic Resistance in Neonatal Disease

Microorganisms
Maternal vaginal and rectal colonization by Streptococcus agalactiae (group B streptococcus, GBS) is the main risk factor for the development of newborn early-onset GBS disease (GBS-EOD).
Roberta Creti, Monica Imperi, Giovanni Gherardi, Giovanna Alfarone, Ilaria Marani, Caterina Vocale, Alberto Berardi, Serena Truocchio, Francesca Miselli   +8 more
doaj   +1 more source

Synthesis of Streptococcus pneumoniae serotype 9V oligosaccharide antigens

Beilstein Journal of Organic Chemistry, 2020
Streptococcus pneumoniae (SP) bacteria cause serious invasive diseases. SP bacteria are covered by a capsular polysaccharide (CPS) that is a virulence factor and the basis for SP polysaccharide and glycoconjugate vaccines.
Sharavathi G. Parameswarappa, Claney L. Pereira, Peter H. Seeberger   +2 more
doaj   +1 more source

Analysis of immunogenicity and purification methods in conjugated polysaccharide vaccines: a new approach in fighting pathogenic bacteria

Frontiers in Immunology
Carbohydrates are commonly found in conjunction with lipids or proteins, resulting in the formation of glycoconjugates such as glycoproteins, glycolipids, and proteoglycans.
Arya Sheikhi, Arya Sheikhi, Mina Shirmohammadpour, Mina Shirmohammadpour, Nima Mahdei Nasirmahalleh, Bahman Mirzaei   +5 more
doaj   +1 more source

Compatibility and Stability of a Shigella Polysaccharide—Protein Conjugate Antigen Formulated with Aluminum Salt and CpG 1018^® Adjuvants

Vaccines
This study evaluated the formulation and stability of a quadrivalent glycoconjugate Shigella vaccine candidate based on four predominant strains (S. flexneri; 2a, 3a, and 6, and S. sonnei) covering ~64% of global Shigella infections.
Poorva Taskar, Prashant Kumar, Brandy Dotson, Anup Datta, Shangdong Guo, Giriraj Chalke, Richa Puri, Harshita Seth, Benjamin Wizel, Sangeeta B. Joshi, David B. Volkin   +10 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development

Molecules, 2018
During the last decade there has been a growing interest in glycoimmunology, a relatively new research field dealing with the specific interactions of carbohydrates with the immune system. Pathogens’ cell surfaces are covered by a thick layer of oligo- and polysaccharides that are crucial virulence factors, as they mediate receptors binding on host ...
Cinzia Colombo, Olimpia Pitirollo, Luigi Lay   +2 more
openaire   +3 more sources

Vaccines based on the cell surface carbohydrates of pathogenic bacteria

Anais da Academia Brasileira de Ciências, 2005
Glycoconjugate vaccines, in which a cell surface carbohydrate from a micro-organism is covalently attached to an appropriate carrier protein are proving to be the most effective means to generate protective immune responses to prevent a wide range of ...
Jones Christopher
doaj  

Investigation into the efficiency of diverse N‐linking oligosaccharyltransferases for glycoengineering using a standardised cell‐free assay

Microbial Biotechnology
The application of bacterial oligosaccharyltransferases (OSTs) such as the Campylobacter jejuni PglB for glycoengineering has attracted considerable interest in glycoengineering and glycoconjugate vaccine development.
Burhan Lehri, Elizabeth Atkins, Timothy A. Scott, Sherif Abouelhadid, Brendan W. Wren, Jon Cuccui   +5 more
doaj   +1 more source

The Acute Immune Response in Sheep Following Immunization with Toxoplasma gondii Tachyzoites or Parasite-Derived Glycoconjugates

Veterinary Sciences
Toxoplasmosis is a relevant parasitic infection in sheep, with ovine meat an important source of human exposure. Accurate detection of the early immune response to Toxoplasma gondii is essential for preventing reproductive losses and improving diagnostic
Patrícia Oliveira Meira-Santos, Gabriela Cruz Piedade, Maria Tereza Guedes, Dan Loureiro, José Tadeu Raynal, Roberto Meyer, Letícia Vicentini, Luiz Soares, Blima Fux, Ricardo Wagner Portela   +9 more
doaj   +1 more source

Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis

Biology Direct
Background To create a dual-acting vaccine that can fight against tuberculosis, we combined antigenic arabino-mannan analogues with the Ag85B protein. To start the process, we studied the impact of modifying different parts of the Ag85B protein on its ...
Roberta Bernardini, Sara Tengattini, Zhihao Li, Luciano Piubelli, Teodora Bavaro, Anamaria Bianca Modolea, Maurizio Mattei, Paola Conti, Stefano Marini, Yongmin Zhang, Loredano Pollegioni, Caterina Temporini, Marco Terreni   +12 more
doaj   +1 more source