Results 21 to 30 of about 220,176 (131)
Glycoconjugate vaccines against Salmonella enterica serovars and Shigella species: existing and emerging methods for their analysis. [PDF]
Biophys Rev, 2021 The global spread of enteric disease, the increasingly limited options for antimicrobial treatment and the need for effective eradication programs have resulted in an increased demand for glycoconjugate enteric vaccines, made with carbohydrate-based ...
Bazhenova A +3 more
europepmc +2 more sources
Recent advances in the production of recombinant glycoconjugate vaccines. [PDF]
NPJ Vaccines, 2019 Glycoconjugate vaccines against bacteria are one of the success stories of modern medicine and have led to a significant reduction in the global occurrence of bacterial meningitis and pneumonia.
Kay E, Cuccui J, Wren BW.
europepmc +2 more sources
Synthetic Glycans to Improve Current Glycoconjugate Vaccines and Fight Antimicrobial Resistance. [PDF]
Chem Rev, 2022 Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides Pseudomonas aeruginosa, non-typhoidal Salmonella, and Staphylococcus aureus, and the ...
Del Bino L +6 more
europepmc +2 more sources
Polysaccharide Structure Dictates Mechanism of Adaptive Immune Response to Glycoconjugate Vaccines [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 Dennis L Kasper +2 more
exaly +2 more sources
Frontiers in Molecular Biosciences, 2021 2-Aminoethyl glycoside of the pseudotetrasaccharide α-d-Glcp-(1→3)-α-l-Rhap-(1→3)-d-Rib-ol-(5-P-2)-α-d-Galp corresponding to a repeating unit of the Streptococcus pneumoniae type 6A capsular polysaccharide has been synthesized.
Elena V. Sukhova +5 more
doaj +1 more source
Frontiers in Immunology, 2020 A number of studies have demonstrated the limited efficacy of S. pneumoniae type 3 capsular polysaccharide (CP) in the 13-valent pneumococcal conjugate vaccine against serotype 3 invasive pneumococcal diseases and carriage.
Ekaterina A. Kurbatova +9 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 Glycosylation is one of the most common post-translational modifications of proteins across all kingdoms of life. Diverse monosaccharides and polysaccharides can be attached to a range of amino acid residues generating N-glycosylation, O-glycosylation, C-
Riye Lu +4 more
doaj +1 more source
Synthetic carbohydrate-based vaccines: challenges and opportunities
Journal of Biomedical Science, 2020 Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate vaccines are mainly obtained from bacterial ...
Ravinder Mettu +2 more
doaj +1 more source
A Synthetic β-Mannan Epitope Enables Immunization and Detection of Candida auris. [PDF]
Angew Chem Int Ed EnglA synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Reuber EE +8 more
europepmc +3 more sources
Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal <i>Salmonella</i>. [PDF]
Proc Natl Acad Sci U S A, 2018 Nontyphoidal Salmonellae cause a devastating burden of invasive disease in sub-Saharan Africa with high levels of antimicrobial resistance. Vaccination has potential for a major global health impact, but no licensed vaccine is available.
Micoli F +12 more
europepmc +6 more sources