Results 81 to 90 of about 220,176 (131)

The influence of conjugation variables on the design and immunogenicity of a glycoconjugate vaccine against Salmonella Typhi.

PLoS ONE, 2017
In recent years there have been major efforts to develop glycoconjugate vaccines based on the Vi polysaccharide that will protect against Salmonella enterica Typhi infections, particularly typhoid fever, which remains a major public health concern in low-
M Arcuri, R Di Benedetto, A F Cunningham, A Saul, C A MacLennan, F Micoli   +5 more
doaj   +1 more source

An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia

Journal of Immunology Research, 2018
There is a requirement for an efficacious vaccine to protect people against infection from Francisella tularensis, the etiological agent of tularemia. The lipopolysaccharide (LPS) of F.
Laura E. Marshall, Michelle Nelson, Carwyn H. Davies, Adam O. Whelan, Dominic C. Jenner, Madeleine G. Moule, Carmen Denman, Jon Cuccui, Timothy P. Atkins, Brendan W. Wren, Joann L. Prior   +10 more
doaj   +1 more source

Expanding polysaccharide-protein coupling of glycoconjugate vaccines. [PDF]

J Biol Chem, 2022
Berti F.
europepmc   +1 more source

Direct Cloning of Bacterial Surface Polysaccharide Gene Cluster for One-Step Production of Glycoconjugate Vaccine

, 2018
Bacterial pathogen infections are fast-growing public health threats and worldwide problems. Glycoconjugate vaccines are among the most effective means in combating such infections.
Huajie Zhang (618098), Lei Li, Lei Li (29537), Min Chen (147733), Peng George Wang (256049), Huajie Zhang, Zhongrui Ma (618097), Min Chen, Zhongrui Ma, Peng George Wang   +9 more
core   +1 more source

Impact of acetylation of carbohydrate epitopes on the immunogenicity of glycoconjugate vaccines

Glycoconjugate vaccines are among the safest and most successful vaccines developed during the last 40 years. They are composed by poly- or oligosaccharides covalently linked to a carrier protein, which provides T-cell epitopes that are necessary for the
Capialbi, Daniela Eloisa
core   +1 more source

Glycoconjugate vaccines: classic and novel approaches. [PDF]

Glycoconj J, 2021
Adamo R.
europepmc   +1 more source

Evaluation of a FlpA Glycoconjugate Vaccine with Ten N-Heptasaccharide Glycan Moieties to reduce Campylobacter jejuni Colonisation in Chickens

Vaccines
Campylobacter is a major cause of acute gastroenteritis in humans, and infections can be followed by inflammatory neuropathies and other sequelae. Handling or consumption of poultry meat is the primary risk factor for human campylobacteriosis, and C ...
Ricardo Corona-Torres, Prerna Vohra, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Marta Mauri, Jon Cuccui, Lonneke Vervelde, Brendan W. Wren, Mark P. Stevens   +9 more
doaj   +1 more source

Further Insights into the Measurement of Free Polysaccharide in Meningococcal Conjugate Vaccines

Vaccines
Objectives: The purpose of this study was to further characterize the ultrafiltration (UF) method for determining free saccharide levels in glycoconjugate vaccines and compare it with other methods used for the determination of free saccharide levels in ...
Nicola J. Beresford, Gianluigi De Benedetto, Kay Lockyer, Fang Gao, Karena Burkin, Karan Lalwani, Barbara Bolgiano   +6 more
doaj   +1 more source

Recent advances on smart glycoconjugate vaccines in infections and cancer. [PDF]

FEBS J, 2022
Anderluh M, Berti F, Bzducha-Wróbel A, Chiodo F, Colombo C, Compostella F, Durlik K, Ferhati X, Holmdahl R, Jovanovic D, Kaca W, Lay L, Marinovic-Cincovic M, Marradi M, Ozil M, Polito L, Reina JJ, Reis CA, Sackstein R, Silipo A, Švajger U, Vaněk O, Yamamoto F, Richichi B, van Vliet SJ.   +24 more
europepmc   +1 more source

Engineering a suite of E. coli strains for enhanced expression of bacterial polysaccharides and glycoconjugate vaccines. [PDF]

Microb Cell Fact, 2022
Kay EJ, Mauri M, Willcocks SJ, Scott TA, Cuccui J, Wren BW.   +5 more
europepmc   +1 more source