Results 21 to 30 of about 76,168 (194)

Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle [PDF]

open access: yesEuropean Journal of Biochemistry, 1982
Three glycogen synthase kinases termed glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5, which are distinct from cyclic‐AMP‐dependent protein kinase and phosphorylase kinase,have been purified and characterised. Their activities are unaffected by Ca2+, calmodulin, cyclic nucleotides and the inhibitor protein of ...
Cohen P   +5 more
openaire   +3 more sources

Control of glycogen content in retina: allosteric regulation of glycogen synthase. [PDF]

open access: yesPLoS ONE, 2012
Retinal tissue is exceptional because it shows a high level of energy metabolism. Glycogen content represents the only energy reserve in retina, but its levels are limited.
Ixchel Osorio-Paz   +2 more
doaj   +1 more source

Islet Transplantation under the Kidney Capsule Corrects the Defects in Glycogen Metabolism in Both Liver and Muscle of Streptozocin-Diabetic Rats

open access: yesCell Transplantation, 2002
Insulin-deficient rats are characterized by multiple defects in the pathway of glycogen synthesis and breakdown in both liver and skeletal muscle. The aim of this study was to clarify whether islet transplantation under the kidney capsule, which is ...
Margherita Matarazzo   +7 more
doaj   +1 more source

A whole-body model for glycogen regulation reveals a critical role for substrate cycling in maintaining blood glucose homeostasis.

open access: yesPLoS Computational Biology, 2011
Timely, and sometimes rapid, metabolic adaptation to changes in food supply is critical for survival as an organism moves from the fasted to the fed state, and vice versa.
Ke Xu   +4 more
doaj   +1 more source

Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease

open access: yesMolecular Therapy: Nucleic Acids, 2014
Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA; EC 3.2.1.20) and the resultant progressive lysosomal accumulation of glycogen in skeletal and cardiac muscles.
Nicholas P Clayton   +9 more
doaj   +1 more source

Huddling alleviates the decrease in glycogen and lipid content in the liver of Brandt’s vole caused by mild cold environment [PDF]

open access: yesZoologia (Curitiba)
Low/cold ambient temperatures can induce hepatic damage in mammals, prompting the evolution of huddling as an adaptive strategy among small mammals to survive cold conditions in the wild.
Jin-Hui Xu   +6 more
doaj   +1 more source

Glycogen Metabolism and Its Role in Growth and Encystation in Entamoeba histolytica

open access: yesLife, 2023
Entamoeba histolytica is a parasitic protozoan that causes diarrheal disease in approximately 100 million people worldwide every year. E. histolytica has two forms, the growing trophozoite and the infectious cyst.
Jordan Wesel, Cheryl Ingram-Smith
doaj   +1 more source

Glycogen storage disease type 0 due to a novel frameshift mutation in glycogen synthase 2 (GYS2) gene in a child presenting with fasting hypoglycemia and postprandial hyperglycemia

open access: yesThe Turkish Journal of Pediatrics, 2018
Glycogen storage disease type 0 (GSD0) has been considered a rare disorder, it is characterized with ketotic hypoglycemia after prolonged fasting and postprandial hyperglycemia.
Bülent Hacıhamdioğlu   +4 more
doaj   +1 more source

Molecular basis of impaired glycogen metabolism during ischemic stroke and hypoxia. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Ischemic stroke is the combinatorial effect of many pathological processes including the loss of energy supplies, excessive intracellular calcium accumulation, oxidative stress, and inflammatory responses.
Mohammed Iqbal Hossain   +2 more
doaj   +1 more source

Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. [PDF]

open access: yesPLoS ONE, 2010
When oxygen becomes limiting, cells reduce mitochondrial respiration and increase ATP production through anaerobic fermentation of glucose. The Hypoxia Inducible Factors (HIFs) play a key role in this metabolic shift by regulating the transcription of ...
Nuria Pescador   +12 more
doaj   +1 more source

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