Glycogen synthase isoforms in Synechocystis sp. PCC6803: identification of different roles to produce glycogen by targeted mutagenesis. [PDF]
PLoS ONE, 2014 Synechocystis sp. PCC6803 belongs to cyanobacteria which carry out photosynthesis and has recently become of interest due to the evolutionary link between bacteria and plant species.
Sang-Ho Yoo +4 more
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Interaction between glycogenin and glycogen synthase [PDF]
Archives of Biochemistry and Biophysics, 2006 Glycogen synthase plays a key role in regulating glycogen metabolism. In a search for regulators of glycogen synthase, a yeast two-hybrid study was performed. Two glycogen synthase-interacting proteins were identified in human skeletal muscle, glycogenin-1, and nebulin.
Peter J. Roach +2 more
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Mediators of Inflammation, 2012 This study investigated the relationship between antiapoptotic activities induced by activated protein C and endoplasmic reticulum stress. In this study, it was observed that activated protein C elicited a rise in glucose-regulated protein 78 and ...
Liang Luo +6 more
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Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase [PDF]
Biochemical Journal, 2000 We have used recombinant adenoviruses (AdCMV-RLGS and AdCMV-GK) to overexpress the liver isoforms of glycogen synthase (GS) and glucokinase (GK) in primary cultured rat hepatocytes. Glucose activated overexpressed GS in a dose-dependent manner and caused the accumulation of larger amounts of glycogen in the AdCMV-RLGS-treated hepatocytes.
Joan J. Guinovart +2 more
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The role of glycogen phosphorylase in glycogen biogenesis in skeletal muscle after exercise
Sports Medicine and Health Science, 2023 Initially it was believed that phosphorylase was responsible for both glycogen breakdown and synthesis in the living cell. The discovery of glycogen synthase and McArdle's disease (lack of phosphorylase activity), together with the high Pi/glucose 1-P ...
Abram Katz
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A RARE CAUSE OF BOTH HYPO AND HYPERGLYCEMIA; GLYCOGEN STORAGE DISEASE TYPE 0: A CASE REPORT
İstanbul Tıp Fakültesi Dergisi, 2021 Glycogen-storage disease type 0A is a rare autosomal recessively inherited disease resulting from a hepatic glycogen synthase enzyme deficiency.
Meryem Karaca, Halil Aslan
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PLoS Pathogens, 2013 The filamentous fungus Magnaporthe oryzae is the causal agent of rice blast disease. Here we show that glycogen metabolic genes play an important role in plant infection by M. oryzae.
Muhammad Badaruddin +5 more
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Aeromonas surface glucan attached through the O-antigen ligase represents a new way to obtain UDP-glucose. [PDF]
PLoS ONE, 2012 We previously reported that A. hydrophila GalU mutants were still able to produce UDP-glucose introduced as a glucose residue in their lipopolysaccharide core. In this study, we found the unique origin of this UDP-glucose from a branched α-glucan surface
Susana Merino +5 more
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Fluoride as a Potential Repressor of Glycogen Metabolism in Skeletal Muscle Cell Line CCL136
Molecules, 2023 The exposure of humans to fluorine is connected with its presence in the air, food and water. It is well known that fluorides even at a low concentration but with long time exposure accumulate in the body and lead to numerous metabolic disorders ...
Izabela Gutowska +7 more
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Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. [PDF]
PLoS Biology, 2013 Several myopathies are associated with defects in autophagic and lysosomal degradation of glycogen, but it remains unclear how glycogen is targeted to the lysosome and what significance this process has for muscle cells.
Jonathan Zirin +2 more
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