Results 41 to 50 of about 81,425 (291)

Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance [PDF]

, 2016
Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus of glycoprotein and glycolipid acceptors.
Aja, Susan, Aoki, Kazuhiro, Lei, Xia, Lopez, Pablo, Ronnett, Gabriele V, Schnaar, Ronald L., Seldin, Marcus M., Wong, G. William   +7 more
core   +1 more source

A Potent CD1d-binding Glycolipid for iNKT-Cell-based Therapy Against Human Breast Cancer [PDF]

, 2019
Background/Aim: Invariant natural killer T-cells (iNKT) stimulated by CD1d-binding glycolipids have been shown to exert antitumor effects by a number of studies in a mouse model.
Brutkiewicz, Randy R., Liu, Jianyun, Seki, Toshiyuki, Tsuji, Moriya   +3 more
core   +1 more source

Determination of lipid-bound sulfate by ion chromatography and its application to quantification of sulfolipids from kidneys of various mammalian species

Journal of Lipid Research, 2001
A variety of procedures have been developed for determining the sulfate ester content of various biomolecules. Ion chromatography (IC), that is, quantitation of ionic substances by ion conductimetry after separation by anion-exchange chromatography, has ...
Keiko Tadano-Aritomi, Toshiyuki Hikita, Atsushi Suzuki, Hidenao Toyoda, Toshihiko Toida, Toshio Imanari, Ineo Ishizuka   +6 more
doaj   +1 more source

Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]

, 1994
. Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard, Dearey, Elisabeth Ann, Korndörfer, Andrea, Müller, Günter   +3 more
core   +3 more sources

The History of Carbohydrates in Type I Allergy

Frontiers in Immunology, 2020
Although first described decades ago, the relevance of carbohydrate specific antibodies as mediators of type I allergy had not been recognized until recently.
Miriam Hils, Florian Wölbing, Christiane Hilger, Jörg Fischer, Nils Hoffard, Tilo Biedermann, Tilo Biedermann   +6 more
doaj   +1 more source

Stimulation of Natural Killer T Cells by Glycolipids

Molecules, 2013
Natural killer T (NKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d protein. The initial discovery of immunostimulatory glycolipids from a marine sponge and the T cells that respond to the compounds has led to ...
Brian L. Anderson, Luc Teyton, Albert Bendelac, Paul B. Savage   +3 more
doaj   +1 more source

Planococcus Species – An Imminent Resource to Explore Biosurfactant and Bioactive Metabolites for Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2020
The marine environment represents a well-off and diverse group of microbes, which offers an enormous natural bioactive compounds of commercial importance.
Samadhan Waghmode, Mangesh Suryavanshi, Deepansh Sharma, Surekha K. Satpute   +3 more
doaj   +1 more source

Water-soluble trehalose glycolipids show superior Mincle binding and signaling but impaired phagocytosis and IL-1β production

Frontiers in Molecular Biosciences, 2022
The tremendous potential of trehalose glycolipids as vaccine adjuvants has incentivized the study of how the structures of these ligands relate to their Mincle-mediated agonist activities.
M. A. Thathsaranie P. Manthrirathna, Emma M. Dangerfield, Emma M. Dangerfield, Shigenari Ishizuka, Shigenari Ishizuka, Aodhamair Woods, Brenda S. Luong, Brenda S. Luong, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki, Sho Yamasaki, Mattie S. M. Timmer, Mattie S. M. Timmer, Bridget L. Stocker, Bridget L. Stocker   +15 more
doaj   +1 more source

Kinetics and cellular site of glycolipid loading control [PDF]

, 2009
CD1d-restricted natural killer T cells (NKT cells) possess a wide range of effector and regulatory activities that are related to their ability to secrete both T helper 1 (Th1) cell- and Th2 cell-type cytokines.
Arora, Pooja, Baena, Andres, Baine, Ian, Bricard, Gabriel, Goldberg, Michael F., Im, Jin S., Jerud, Elliot S., Molano, Alberto, Ndonye, Rachel M., Venkataswamy, Manjunatha M., Yu, Karl O.A.   +10 more
core  

Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes [PDF]

, 2016
Objective: To characterize the patterns of autoantibodies to glycolipid complexes in a large cohort of Guillain-Barré syndrome (GBS) and control samples collected in Bangladesh using a newly developed microarray technique.
Endtz, Hubert P., Halstead, Susan K., Islam, Mohammad B., Islam, Zhahirul, Jacobs, Bart C., Jahan, Israt, Kalna, Gabriela, Mohammad, Quazi D., Willison, Hugh J.   +8 more
core   +5 more sources