Results 91 to 100 of about 16,721 (247)
The FEBS Journal, EarlyView.We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher +7 more
wiley +1 more source
Nature Communications, 2016 Some virulent strains of Campylobacter jejuni possess a putative chemotaxis receptor, Tlp11, of unknown function. Here the authors show that Tlp11 specifically interacts with galactose and is required for the chemotaxis response of C. jejunito galactose.
Christopher J. Day +9 more
doaj +1 more source
The FEBS Journal, EarlyView.NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu +9 more
wiley +1 more source
Frontiers in Oncology, 2019 Aberrant glycosylation is not only a feature of malignant cell transformation, but also plays an important role in metastasis. In the present study, an integrated strategy combining the lectin microarrays and lectin cytochemistry was employed to ...
Hanjie Yu +14 more
doaj +1 more source
Continuous-Flow Biochemical Reactors: Biocatalysis, Bioconversion, and Bioanalytical Applications Utilizing Immobilized Microfluidic Enzyme Reactors [PDF]
, 2015 The utilization of continuous-flow biochemical reactors, including biocatalysis, biotransformation, and biochemical interaction based flow-analytical systems, and enzyme reactors are recently the focus of attention to produce fine biochemicals and also ...
Guttman, András, Hajba, László
core +1 more source
Fungal ecology in the age of 'omics
New Phytologist, EarlyView.Summary The advancement of technology in recent decades has given us an unprecedented ability to observe the natural world. With modern sequencing and bioinformatics technologies, we can obtain more information about the microscopic world, and its interactions with the macroscopic world, than ever before.
Brontë R. Shelton +12 more
wiley +1 more source
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Marine Drugs, 2012 Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj +1 more source
Parasite Glycobiology:A Bittersweet Symphony [PDF]
, 2015 Human infections caused by parasitic protozoans and helminths are among the world's leading causes of death. More than a million people die each year from diseases like malaria and neglected tropical diseases like leishmaniasis, trypanosomiasis, and ...
Acosta-Serrano, Alvaro +10 more
core +7 more sources
What Can N-glycomics and N-glycoproteomics of Cerebrospinal Fluid Tell Us about Alzheimer Disease? [PDF]
, 2021 Stefan Gaunitz +2 more
openalex +1 more source
Advanced Science, Volume 13, Issue 6, 30 January 2026.Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce +8 more
wiley +1 more source