Results 11 to 20 of about 49,301 (226)

Glycopeptide Antibiotics: Structural and Functional Aspects, Human Medicinal Use, and Standardisation

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2023
In recent years, glycopeptide antibiotics have been widely used to treat severe bacterial infections. The long-term use of first-generation antibiotics of this group (vancomycin, teicoplanin) has contributed to the emergence of bacteria resistant to them.
O. N. Vysochanskaya   +2 more
doaj   +1 more source

Glycomic analysis of high density lipoprotein shows a highly sialylated particle. [PDF]

open access: yes, 2014
Many of the functional proteins and lipids in high density lipoprotein (HDL) particles are potentially glycosylated, yet very little is known about the glycoconjugates of HDL.
German, J Bruce   +6 more
core   +1 more source

Bacterial Cell Wall Analogue Peptides Control the Oligomeric States and Activity of the Glycopeptide Antibiotic Eremomycin: Solution NMR and Antimicrobial Studies

open access: yesPharmaceuticals, 2021
For some time, glycopeptide antibiotics have been considered the last line of defense against Methicillin-resistant Staphylococcus aureus (MRSA). However, vancomycin resistance of Gram-positive bacteria is an increasingly emerging worldwide health ...
László Izsépi   +6 more
doaj   +1 more source

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

open access: yes, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC   +6 more
core   +1 more source

Central venous catheter related infections: Risk factors and the effect of glycopeptide antibiotics

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2003
Backround We undertook a prospective study of all new central venous catheters inserted into patients in the intensive care units, in order to identify the risk factors and to determine the effect of glycopeptide antibiotics on catheter – related ...
Eraksoy Haluk   +6 more
doaj   +1 more source

A Vancomycin HPLC Assay for Use in Gut Microbiome Research

open access: yesMicrobiology Spectrum, 2022
The human microbiome project has revolutionized our understanding of the interaction between commensal microbes and human health. By far, the biggest perturbation of the microbiome involves use of broad-spectrum antibiotics excreted in the gut.
Chenlin Hu   +2 more
doaj   +1 more source

Epitopes of MUC1 Tandem Repeats in Cancer as Revealed by Antibody Crystallography: Toward Glycopeptide Signature-Guided Therapy

open access: yesMolecules, 2018
Abnormally O-glycosylated MUC1 tandem repeat glycopeptide epitopes expressed by multiple types of cancer have long been attractive targets for therapy in the race against genetic mutations of tumor cells.
Dapeng Zhou   +3 more
doaj   +1 more source

Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]

open access: yes, 2020
Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich   +7 more
core   +2 more sources

Glycopeptide antibiotic drug stability in aqueous solution

open access: yesAAPS Open, 2022
Glycopeptide antimicrobials are a class of naturally occurring or semi-synthetic glycosylated products that have shown antibacterial activity against gram-positive organisms by inhibiting cell-wall synthesis.
Sardar M. Jakaria   +2 more
doaj   +1 more source

Does Vancomycin Resistance Increase Mortality? Clinical Outcomes and Predictive Factors for Mortality in Patients with Enterococcus faecium Infections

open access: yesAntibiotics, 2021
The prevalence of enterococcal infection, especially E. faecium, is increasing, and the issue of the impact of vancomycin resistance on clinical outcomes is controversial.
Jatapat Hemapanpairoa   +3 more
doaj   +1 more source

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