Results 101 to 110 of about 48,098 (265)
Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen +4 more
wiley +1 more source
Characterization of core fucosylation via sequential enzymatic treatments of intact glycopeptides and mass spectrometry analysis [PDF]
Liwei Cao +14 more
openalex +1 more source
A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Michael E. Dolan +6 more
wiley +1 more source
Glycopeptide resistance among coagulase- negative staphylococci that cause bacteremia: epidemiological and clinical findings from a case-control study [PDF]
A 1-year prospective case-control study (ratio of control patients to case patients, 3:1) was performed to assess the incidence, risk factors, and genotypic patterns of bacteremia caused by glycopeptide-resistant coagulasenegative staphylococci (CoNS ...
Bettio, Manola +9 more
core +1 more source
ABSTRACT Background Vancomycin (VCM), a first‐line treatment option for infections caused by methicillin‐resistant Staphylococcus aureus, has been reported to cause nephrotoxicity even within therapeutic concentration ranges. Traditional therapeutic drug monitoring strategies rely primarily on the area under the concentration–time curve (AUC), without ...
Yoshihiko Matsuki +6 more
wiley +1 more source
Annotation of Peptide Structures Using SMILES and Other Chemical Codes–Practical Solutions
Contemporary peptide science exploits methods and tools of bioinformatics, and cheminformatics. These approaches use different languages to describe peptide structures—amino acid sequences and chemical codes (especially SMILES), respectively.
Piotr Minkiewicz +2 more
doaj +1 more source
Increased sialylation of site specific O-glycoforms of hemopexin in liver disease [PDF]
Additional file 1 . Supplemental methods, figures and tables. SM 1.1. Mapping of the O-glycosylation sites. SM 1.2. Beta elimination and mass spectrometric analysis of HPX O-glycans. Table S1.
Coleman I. Smith +9 more
core +2 more sources
Framework diagram of CDvan informed by MCS (Eucast, European committee for antimicrobial susceptibility testing; CLSI, clinical and laboratory standard institute). ABSTRACT Vancomycin (VAN) remains the first‐line treatment for methicillin‐resistant, multidrug‐resistant gram‐positive bacterial infections, even among cancer patients.
Xiangqing Song +3 more
wiley +1 more source
For investigations on the biological functions of oligosaccharides and peptidomimetics, new asparagine-based mono- and disaccharides containing glycopeptides were prepared in solution.
Laura Sršan, Thomas Ziegler
doaj +1 more source
Antibiotic resistance mechanisms inform discovery: identification and characterization of a novel amycolatopsis strain producing ristocetin. [PDF]
Discovering new antibiotics is a major scientific challenge, made increasingly urgent by the continued development of resistance in bacterial pathogens.
Cheng, Jinhua +5 more
core +2 more sources

