Results 111 to 120 of about 576 (126)

The Contribution of Echocardiography to the Diagnosis and Prognosis Stratification of Diabetic Cardiomyopathy. [PDF]

Diagnostics (Basel)
Ioannou M, Karelas D, Kalesi AE, Parpas G, Papanastasiou CA, Papadopoulos CH, Mouzarou A, Kadoglou NPE.   +7 more
europepmc   +1 more source

Decoding the ubiquitination-immunity axis in idiopathic pulmonary fibrosis: diagnostic insights and therapeutic implications. [PDF]

Respir Res
He W, Feng C, Liu M, Qin H, Wu Y, Deng C, Zhu X.   +6 more
europepmc   +1 more source

Retinal Autophagy for Sustaining Retinal Integrity as a Proof of Concept for Age-Related Macular Degeneration. [PDF]

Int J Mol Sci
Pinelli R, Lazzeri G, Berti C, Biagioni F, Scaffidi E, Ferrucci M, Bumah VV, Fornai F.   +7 more
europepmc   +1 more source

Neurological glycogen storage diseases and emerging therapeutics. [PDF]

Neurotherapeutics
Colpaert M, Singh PK, Donohue KJ, Pires NT, Fuller DD, Corti M, Byrne BJ, Sun RC, Vander Kooi CW, Gentry MS.   +9 more
europepmc   +1 more source

A novel CD71 Centyrin:Gys1 siRNA conjugate reduces glycogen synthesis and glycogen levels in a mouse model of Pompe disease. [PDF]

Mol Ther
Holt BD, Elliott SJ, Meyer R, Reyes D, O'Neil K, Druzina Z, Kulkarni S, Thurberg BL, Nadler SG, Pederson BA.   +9 more
europepmc   +1 more source

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Glycophagy mediated glucose-induced changes of hepatic glycogen metabolism via OGT1-AKT1-FOXO1Ser238 pathway

Journal of Nutritional Biochemistry, 2023
Glycophagy is the autophagy degradation of glycogen. However, the regulatory mechanisms for glycophagy and glucose metabolism remain unexplored. Herein, we demonstrated that high-carbohydrate diet (HCD) and high glucose (HG) incubation induced glycogen accumulation, protein kinase B (AKT)1 expression and AKT1-dependent phosphorylation of forkhead ...
Li-Xiang Wu, Yichuang Xu, Kostas Pantopoulos   +2 more
exaly   +3 more sources

Glycophagy: An emerging target in pathology

Clinica Chimica Acta, 2018
Autophagy, a highly conserved self-digestion process, is initially regarded as non-selectively sequestering and degradation cytoplasmic contents. Nowadays, many kinds of selective autophagy have been found in response to various physiological cues such as mitophagy, reticulophagy and glycophagy.
Pingbo Yao, Lin-xi Chen
exaly   +3 more sources

D‐pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin‐mediated endoplasmic reticulum stress and glycophagy signaling pathway

Phytotherapy Research
AbstractDiabetic cardiomyopathy (DCM) is an important complication resulting in heart failure and death of diabetic patients. However, there is no effective drug for treatments. This study investigated the effect of D‐pinitol (DP) on cardiac injury using diabetic mice and glycosylation injury of cardiomyocytes and its molecular mechanisms.
Baoying Li
exaly   +3 more sources

Glycophagy: A selective autophagy pathway for glycogen degradation

International Review of Cell and Molecular Biology
exaly   +2 more sources